Variation in human water turnover associated with environmental and lifestyle factors

International Atomic Energy Agency (IAEA) Doubly Labeled Water (DLW) Database Consortium

Research output: Contribution to journalArticlepeer-review

Abstract

Water is essential for survival, but one in three individuals worldwide (2.2 billion people) lacks access to safe drinking water. Water intake requirements largely reflect water turnover (WT), the water used by the body each day. We investigated the determinants of human WT in 5604 people from the ages of 8 days to 96 years from 23 countries using isotope-tracking (2H) methods. Age, body size, and composition were significantly associated with WT, as were physical activity, athletic status, pregnancy, socioeconomic status, and environmental characteristics (latitude, altitude, air temperature, and humidity). People who lived in countries with a low human development index (HDI) had higher WT than people in high-HDI countries. On the basis of this extensive dataset, we provide equations to predict human WT in relation to anthropometric, economic, and environmental factors.

Original languageEnglish
Pages (from-to)909-915
Number of pages7
JournalScience
Volume378
Issue number6622
DOIs
Publication statusPublished - 2022 Nov 25

ASJC Scopus subject areas

  • General

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