Visualization of Atg3 during autophagosome formation in Saccharomyces cerevisiae

Meipin Ngu, Eri Hirata, Kuninori Suzuki*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Background: Atg3 is an E2-like enzyme in the Atg8 system, an autophagy-related ubiquitin-like conjugation system. Results: Atg3 is localized to the isolation membrane, which is an intermediate structure of an autophagosome. Conclusion: Atg3 is likely to play an important role in autophagosome formation at the isolation membrane. Significance: This result provides new insights into the role of the ubiquitin-like system in organelle biogenesis.

Original languageEnglish
Pages (from-to)8146-8153
Number of pages8
JournalJournal of Biological Chemistry
Volume290
Issue number13
DOIs
Publication statusPublished - 2015 Mar 27
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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