Waiakeamide, a cyclic hexapeptide from the sponge Ircinia dendroides

Christina M.S. Mau, Yoichi Nakao, Wesley Y. Yoshida, Paul J. Scheuer, Michelle Kelly-Borges

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Abstract

From the sponge, Ircinia dendroides, collected in Indonesia we isolated a new cyclic hexapeptide, waiakeamide (1). Its structure, consisting of three proline residues, two methionine sulfoxides, and one thiazolylphenylalanine, was elucidated by spectral analysis and chemical degradation. Isolation and structural elucidation of waiakeamide is described.

Original languageEnglish
Pages (from-to)6302-6304
Number of pages3
JournalJournal of Organic Chemistry
Volume61
Issue number18
DOIs
Publication statusPublished - 1996 Sep 6
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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    Mau, C. M. S., Nakao, Y., Yoshida, W. Y., Scheuer, P. J., & Kelly-Borges, M. (1996). Waiakeamide, a cyclic hexapeptide from the sponge Ircinia dendroides. Journal of Organic Chemistry, 61(18), 6302-6304. https://doi.org/10.1021/jo960771e