Wall shear stress distribution inside growing cerebral aneurysm

Tetsuya Tanoue, S. Tateshima, J. P. Villablanca, F. Viñuela, K. Tanishita

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: Hemodynamic stimulation has been suggested to affect the growth of cerebral aneurysms. The present study examined the effects of intra-aneurysmal hemodynamics on aneurysm growth. MATERIALS AND METHODS: Velocity profiles were measured for 2 cases of AcomA aneurysms. Realistically shaped models of these aneurysms were constructed, based on CT angiograms. Flow fields and WSS in the models were measured by using particle image velocimetry and LDV. In 1 case, hemodynamic changes were observed in 4 stages of growth over a 27-month period, whereas no development was observed in the other case. RESULTS: The growing model had a smaller and more stagnant recirculation area than that in the nongrowth model. The WSS was markedly reduced in the enlarging region in the growing models, whereas extremely low WSS was not found in the nongrowth model. In addition, a higher WSSG was consistently observed adjacent to the enlarging region during aneurysm growth. CONCLUSIONS: The results indicated that the flow structure of recirculation itself does not necessarily lead to high likelihood of cerebral aneurysm. However, WSSG and WSS were distinctly different between the 2 cases. Higher WSSG was found surrounding the growing region, and extremely low WSS was found at the growing region of the growing cerebral aneurysm.

Original languageEnglish
Pages (from-to)1732-1737
Number of pages6
JournalAmerican Journal of Neuroradiology
Volume32
Issue number9
DOIs
Publication statusPublished - 2011 Oct
Externally publishedYes

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Intracranial Aneurysm
Aneurysm
Hemodynamics
Growth
Rheology
Angiography

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

Cite this

Tanoue, T., Tateshima, S., Villablanca, J. P., Viñuela, F., & Tanishita, K. (2011). Wall shear stress distribution inside growing cerebral aneurysm. American Journal of Neuroradiology, 32(9), 1732-1737. https://doi.org/10.3174/ajnr.A2607

Wall shear stress distribution inside growing cerebral aneurysm. / Tanoue, Tetsuya; Tateshima, S.; Villablanca, J. P.; Viñuela, F.; Tanishita, K.

In: American Journal of Neuroradiology, Vol. 32, No. 9, 10.2011, p. 1732-1737.

Research output: Contribution to journalArticle

Tanoue, T, Tateshima, S, Villablanca, JP, Viñuela, F & Tanishita, K 2011, 'Wall shear stress distribution inside growing cerebral aneurysm', American Journal of Neuroradiology, vol. 32, no. 9, pp. 1732-1737. https://doi.org/10.3174/ajnr.A2607
Tanoue T, Tateshima S, Villablanca JP, Viñuela F, Tanishita K. Wall shear stress distribution inside growing cerebral aneurysm. American Journal of Neuroradiology. 2011 Oct;32(9):1732-1737. https://doi.org/10.3174/ajnr.A2607
Tanoue, Tetsuya ; Tateshima, S. ; Villablanca, J. P. ; Viñuela, F. ; Tanishita, K. / Wall shear stress distribution inside growing cerebral aneurysm. In: American Journal of Neuroradiology. 2011 ; Vol. 32, No. 9. pp. 1732-1737.
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