Water extract of Houttuynia cordata thunb. Leaves exerts anti-obesity effects by inhibiting fatty acid and glycerol absorption

Mitsuyoshi Miyata, Tomoyuki Koyama, Kazunaga Yazawa

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31 Citations (Scopus)


Houttuynia cordata Thunb. is used in folk medicine for diuresis and detoxification. However, it has not yet been reported to have an anti-obesity effect. We found that the water extract of H. cordata leaves (WEH) inhibited the corn oil-induced increase in plasma triglyceride levels in mice. WEH also inhibited the oleic acidand glycerol-induced increase in the levels of plasma nonesterified fatty acids and glycerol, respectively. Moreover, WEH had anti-obesity effects in mice with high-fat-diet-induced obesity. Therefore, WEH may be able to prevent or reduce obesity induced by a high-fat diet.

Original languageEnglish
Pages (from-to)150-156
Number of pages7
JournalJournal of Nutritional Science and Vitaminology
Issue number2
Publication statusPublished - 2010
Externally publishedYes



  • Anti-obesity
  • Fatty acid
  • Glycerol
  • Houttuynia cordata thunb.
  • Triglyceride

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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