• 1050 引用
  • 13 h指数
19982019

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
Article
2019

Comparison between effects of retroactivity and resource competition upon change in downstream reporter genes of synthetic genetic circuits

Moriya, T., Yamaoka, T., Wakayama, Y., Ayukawa, S., Zhang, Z., Yamamura, M., Wakao, S. & Kiga, D., 2019 3 1, : : Life. 9, 1, 30.

研究成果: Article

公開

Enhancement of binding affinity of folate to its receptor by peptide conjugation

Dharmatti, R., Miyatake, H., Nandakumar, A., Ueda, M., Kobayashi, K., Kiga, D., Yamamura, M. & Ito, Y., 2019 5 1, : : International journal of molecular sciences. 20, 9, 2152.

研究成果: Article

公開
3 引用 (Scopus)
2018

A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-α2b

Imada, T., Moriya, K., Uchiyama, M., Inukai, N., Hitotsuyanagi, M., Masuda, A., Suzuki, T., Ayukawa, S., Tagawa, Y. I., Dohmae, N., Kohara, M., Yamamura, M. & Kiga, D., 2018 1 1, (Accepted/In press) : : ACS Synthetic Biology.

研究成果: Article

Escherichia coli expression, purification, and refolding of human folate receptor α (hFRα) and β (hFRβ)

Dharmatti, R., Miyatake, H., Zhang, C., Ren, X., Yumoto, A., Kiga, D., Yamamura, M. & Ito, Y., 2018 9 1, : : Protein Expression and Purification. 149, p. 17-22 6 p.

研究成果: Article

1 引用 (Scopus)

Horizontal transfer of code fragments between protocells can explain the origins of the genetic code without vertical descent

Froese, T., Campos, J. I., Fujishima, K., Kiga, D. & Virgo, N., 2018 12 1, : : Scientific Reports. 8, 1, 3532.

研究成果: Article

4 引用 (Scopus)
2017
2 引用 (Scopus)
2016

A bacterial continuous culture system based on a microfluidic droplet open reactor

Ito, M., Sugiura, H., Ayukawa, S., Kiga, D. & Takinoue, M., 2016, : : Analytical Sciences. 32, 1, p. 61-66 6 p.

研究成果: Article

1 引用 (Scopus)

Reproducibility of fluorescent expression from engineered biological constructs in E. coli

iGEM Interlab Study Contributors, 2016 3, : : PloS one. 11, 3, e0150182.

研究成果: Article

19 引用 (Scopus)
2015

In vitro selection of a photoresponsive peptide aptamer to glutathione-immobilized microbeads

Tada, S., Zang, Q., Wang, W., Kawamoto, M., Liu, M., Iwashita, M., Uzawa, T., Kiga, D., Yamamura, M. & Ito, Y., 2015 2 1, : : Journal of Bioscience and Bioengineering. 119, 2, p. 137-139 3 p.

研究成果: Article

3 引用 (Scopus)

Two site genetic incorporation of varying length polyethylene glycol into the backbone of one peptide

Zang, Q., Tada, S., Uzawa, T., Kiga, D., Yamamura, M. & Ito, Y., 2015 7 31, : : Chemical Communications. 51, 76, p. 14385-14388 4 p.

研究成果: Article

5 引用 (Scopus)
2014

Effects of downstream genes on synthetic genetic circuits

Moriya, T., Yamamura, M. & Kiga, D., 2014 12 8, : : BMC Systems Biology. 8, 4, S4.

研究成果: Article

4 引用 (Scopus)

Experimental Evolution of a Green Fluorescent Protein Composed of 19 Unique Amino Acids without Tryptophan

Kawahara-Kobayashi, A., Hitotsuyanagi, M., Amikura, K. & Kiga, D., 2014 12 11, : : Origins of Life and Evolution of Biospheres. 44, 2, p. 75-86 12 p.

研究成果: Article

General Applicability of Synthetic Gene-Overexpression for Cell-Type Ratio Control via Reprogramming

Ishimatsu, K., Hata, T., Mochizuki, A., Sekine, R., Yamamura, M. & Kiga, D., 2014 9 19, : : ACS Synthetic Biology. 3, 9, p. 638-644 7 p.

研究成果: Article

5 引用 (Scopus)

Multiple amino acid-excluded genetic codes for protein engineering using multiple sets of tRNA variants

Amikura, K., Sakai, Y., Asami, S. & Kiga, D., 2014 3 21, : : ACS Synthetic Biology. 3, 3, p. 140-144 5 p.

研究成果: Article

5 引用 (Scopus)

Why 20 amino acids?

Amikura, K. & Kiga, D., 2014 6, : : Kobunshi. 63, 6, p. 392-393 2 p.

研究成果: Article

2012

An aptazyme-based molecular device that converts a small-molecule input into an RNA output

Ayukawa, S., Sakai, Y. & Kiga, D., 2012 7 4, : : Chemical Communications. 48, 61, p. 7556-7558 3 p.

研究成果: Article

13 引用 (Scopus)

Simplification of the genetic code: Restricted diversity of genetically encoded amino acids

Kawahara-Kobayashi, A., Masuda, A., Araiso, Y., Sakai, Y., Kohda, A., Uchiyama, M., Asami, S., Matsuda, T., Ishitani, R., Dohmae, N., Yokoyama, S., Kigawa, T., Nureki, O. & Kiga, D., 2012 11 1, : : Nucleic acids research. 40, 20, p. 10576-10584 9 p.

研究成果: Article

14 引用 (Scopus)

Tunability of the ratio of cell states after the synthetic diversification by the diversity generator

Sekine, R., Yamamura, M., Hagiya, M. & Kiga, D., 2012 1 1, : : Communicative and Integrative Biology. 5, 4, p. 393-394 2 p.

研究成果: Article

2011

RTRACS: A modularized RNA-dependent RNA transcription system with high programmability

Ayukawa, S., Takinoue, M. & Kiga, D., 2011 12 20, : : Accounts of Chemical Research. 44, 12, p. 1369-1379 11 p.

研究成果: Article

19 引用 (Scopus)

Tunable synthetic phenotypic diversification on Waddington's landscape through autonomous signaling

Sekine, R., Yamamura, M., Ayukawa, S., Ishimatsu, K., Akama, S., Takinoue, M., Hagiya, M. & Kiga, D., 2011 11 1, : : Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. 17969-17973 5 p.

研究成果: Article

23 引用 (Scopus)
2010

Construction of a genetic AND gate under a new standard for assembly of genetic parts

Ayukawa, S., Kobayashi, A., Nakashima, Y., Takagi, H., Hamada, S., Uchiyama, M., Yugi, K., Murata, S., Sakakibara, Y., Hagiya, M., Yamamura, M. & Kiga, D., 2010 12 2, : : BMC Genomics. 11, SUPPL. 4, S16.

研究成果: Article

10 引用 (Scopus)
2009

Rna oscillator: Limit cycle oscillations based on artificial biomolecular reactions

Takinoue, M., Kiga, D., Shohda, K. I. & Suyama, A., 2009 2 1, : : New Generation Computing. 27, 2, p. 107-127 21 p.

研究成果: Article

7 引用 (Scopus)
2008

A design and feasibility study of reactions comprising DNA molecular machine that walks autonomously by using a restriction enzyme

Sekiguchi, H., Komiya, K., Kiga, D. & Yamamura, M., 2008 9 1, : : Natural Computing. 7, 3, p. 303-315 13 p.

研究成果: Article

1 引用 (Scopus)
35 引用 (Scopus)

Synthetic biology

Kiga, D. & Yamamura, M., 2008 8 1, : : New Generation Computing. 26, 4, p. 347-364 18 p.

研究成果: Article

1 引用 (Scopus)
2007

SYANAC: SYnthetic biological Automaton for Noughts and Crosses

Ayukawa, S., Kobayashi, A., Nakashima, Y., Takagi, H., Hamada, S., Uchiyama, M., Yugi, K., Murata, S., Sakakibara, Y., Hagiya, M., Yamamura, M. & Kiga, D., 2007 8 15, : : IET Synthetic Biology. 1, 1-2, p. 64-67 4 p.

研究成果: Article

2 引用 (Scopus)
2006

Cation-π interaction in the polyolefin cyclization cascade uncovered by incorporating unnatural amino acids into the catalytic sites of squalene cyclase

Morikubo, N., Fukuda, Y., Ohtake, K., Shinya, N., Kiga, D., Sakamoto, K., Asanuma, M., Hirota, H., Yokoyama, S. & Hoshino, T., 2006 10 11, : : Journal of the American Chemical Society. 128, 40, p. 13184-13194 11 p.

研究成果: Article

57 引用 (Scopus)

DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architecture into molecular computing

Komiya, K., Sakamoto, K., Kameda, A., Yamamoto, M., Ohuchi, A., Kiga, D., Yokoyama, S. & Hagiya, M., 2006 1 1, : : BioSystems. 83, 1, p. 18-25 8 p.

研究成果: Article

19 引用 (Scopus)

Translation of 'rare' codons in a cell-free protein synthesis system from Escherichia coli

Chumpolkulwong, N., Sakamoto, K., Hayashi, A., Iraha, F., Shinya, N., Matsuda, N., Kiga, D., Urushibata, A., Shirouzu, M., Oki, K., Kigawa, T. & Yokoyama, S., 2006 3 1, : : Journal of structural and functional genomics. 7, 1, p. 31-36 6 p.

研究成果: Article

22 引用 (Scopus)
2002

An engineered Escherichia coli tyrosyl-tRNA synthetase for site-specific incorporation of an unnatural amino acid into proteins in eukaryotic translation and its application in a wheat germ cell-free system

Kiga, D., Sakamoto, K., Kodama, K., Kigawa, T., Matsuda, T., Yabuki, T., Shirouzu, M., Harada, Y., Nakayama, H., Takio, K., Hasegawa, Y., Endo, Y., Hirao, I. & Yokoyama, S., 2002 7 23, : : Proceedings of the National Academy of Sciences of the United States of America. 99, 15, p. 9715-9720 6 p.

研究成果: Article

137 引用 (Scopus)

Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells

Sakamoto, K., Hayashi, A., Sakamoto, A., Kiga, D., Nakayama, H., Soma, A., Kobayashi, T., Kitabatake, M., Takio, K., Saito, K., Shirouzu, M., Hirao, I. & Yokoyama, S., 2002 11 1, : : Nucleic acids research. 30, 21, p. 4692-4699 8 p.

研究成果: Article

公開
173 引用 (Scopus)
2001

Shifted positioning of the anticodon nucleotide residues of amber suppressor tRNA species by Escherichia coli arginyl-tRNA synthetase

Kiga, D., Sakamoto, K., Sato, S., Hirao, I. & Yokoyama, S., 2001 12 22, : : European Journal of Biochemistry. 268, 23, p. 6207-6213 7 p.

研究成果: Article

6 引用 (Scopus)
2000

Molecular computation by DNA hairpin formation

Sakamoto, K., Gouzu, H., Komiya, K., Kiga, D., Yokoyama, S., Yokomori, T. & Hagiya, M., 2000 5 19, : : Science. 288, 5469, p. 1223-1226 4 p.

研究成果: Article

323 引用 (Scopus)
1999

State transitions by molecules

Sakamoto, K., Kiga, D., Komiya, K., Gouzu, H., Yokoyama, S., Ikeda, S., Sugiyama, H. & Hagiya, M., 1999 10 1, : : BioSystems. 52, 1-3, p. 81-91 11 p.

研究成果: Article

69 引用 (Scopus)
1998

An RNA aptamer to the xanthine/guanine base with a distinctive mode of purine recognition

Kiga, D., Futamura, Y., Sakamoto, K. & Yokoyama, S., 1998 4 1, : : Nucleic acids research. 26, 7, p. 1755-1760 6 p.

研究成果: Article

61 引用 (Scopus)