• 4806 引用
  • 42 h指数
1990 …2019

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
Article
2019

A CCR5 + memory subset within HIV-1-infected primary resting CD4 + T cells is permissive for replication-competent, latently infected viruses in vitro

Terahara, K., Iwabuchi, R., Hosokawa, M., Nishikawa, Y., Takeyama, H., Takahashi, Y. & Tsunetsugu-Yokota, Y., 2019 4 29, : : BMC Research Notes. 12, 1, 242.

研究成果: Article

公開
1 引用 (Scopus)

An estrogen antagonist, cyclofenil, has anti-dengue-virus activity

Tohma, D., Tajima, S., Kato, F., Sato, H., Kakisaka, M., Hishiki, T., Kataoka, M., Takeyama, H., Lim, C. K., Aida, Y. & Saijo, M., 2019 1 22, : : Archives of Virology. 164, 1, p. 225-234 10 p.

研究成果: Article

Enrichment of bacteria and alginate lyase genes potentially involved in brown alga degradation in the gut of marine gastropods

Ito, M., Watanabe, K., Maruyama, T., Mori, T., Niwa, K., Chow, S. & Takeyama, H., 2019 12 1, : : Scientific reports. 9, 1, 2129.

研究成果: Article

1 引用 (Scopus)

Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies

Adachi, Y., Tonouchi, K., Nithichanon, A., Kuraoka, M., Watanabe, A., Shinnakasu, R., Asanuma, H., Ainai, A., Ohmi, Y., Yamamoto, T., Ishii, K. J., Hasegawa, H., Takeyama, H., Lertmemongkolchai, G., Kurosaki, T., Ato, M., Kelsoe, G. & Takahashi, Y., 2019 12 1, : : Nature communications. 10, 1, 3883.

研究成果: Article

公開
6 引用 (Scopus)

High-throughput identification of peptide agonists against GPCRs by co-culture of mammalian reporter cells and peptide-secreting yeast cells using droplet microfluidics

Yaginuma, K., Aoki, W., Miura, N., Ohtani, Y., Aburaya, S., Kogawa, M., Nishikawa, Y., Hosokawa, M., Takeyama, H. & Ueda, M., 2019 12 1, : : Scientific reports. 9, 1, 10920.

研究成果: Article

公開
1 引用 (Scopus)

IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody

Saito, S., Sano, K., Suzuki, T., Ainai, A., Taga, Y., Ueno, T., Tabata, K., Saito, K., Wada, Y., Ohara, Y., Takeyama, H., Odagiri, T., Kageyama, T., Ogawa-Goto, K., Multihartina, P., Setiawaty, V., Pangesti, K. N. A. & Hasegawa, H., 2019 1 1, : : PLoS Pathogens. 15, 1, p. e1007427

研究成果: Article

5 引用 (Scopus)

Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice

Matsumura, T., Ikebe, T., Arikawa, K., Hosokawa, M., Aiko, M., Iguchi, A., Togashi, I., Kai, S., Ohara, S., Ohara, N., Ohnishi, M., Watanabe, H., Kobayashi, K., Takeyama, H., Yamasaki, S., Takahashi, Y. & Ato, M., 2019 4 9, : : Cell Reports. 27, 2, p. 561-571.e6

研究成果: Article

公開
1 引用 (Scopus)
2018
1 引用 (Scopus)

A metabarcoding survey for seasonal picophytoplankton composition in two coral reefs around Sesoko Island, Okinawa, Japan

Nuryadi, H., Nguyen, T. T. M., Ito, M., Okada, N., Wakaoji, S., Maruyama, T., Nakano, Y., Fujimura, H., Takeyama, H. & Suda, S., 2018 12 1, : : Journal of Applied Phycology. 30, 6, p. 3179-3186 8 p.

研究成果: Article

A novel system for constructing a recombinant highly-attenuated Vaccinia virus strain (LC16m8) expressing foreign genes and its application for the generation of LC16m8-based vaccines against herpes simplex virus 2

Omura, N., Yoshikawa, T., Fujii, H., Shibamura, M., Inagaki, T., Kato, H., Egawa, K., Harada, S., Yamada, S., Takeyama, H. & Saijo, M., 2018 1 1, : : Japanese Journal of Infectious Diseases. 71, 3, p. 229-233 5 p.

研究成果: Article

1 引用 (Scopus)

Combinatory use of distinct single-cell RNA-seq analytical platforms reveals the heterogeneous transcriptome response

Kashima, Y., Suzuki, A., Liu, Y., Hosokawa, M., Matsunaga, H., Shirai, M., Arikawa, K., Sugano, S., Kohno, T., Takeyama, H., Tsuchihara, K. & Suzuki, Y., 2018 12 1, : : Scientific Reports. 8, 1, 3482.

研究成果: Article

4 引用 (Scopus)

Effects of short-term endurance exercise on gut microbiota in elderly men

Taniguchi, H., Tanisawa, K., Sun, X., Kubo, T., Hoshino, Y., Hosokawa, M., Takeyama, H. & Higuchi, M., 2018 12 1, : : Physiological Reports. 6, 23, e13935.

研究成果: Article

5 引用 (Scopus)

Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages

The Alzheimer's Disease Neuroimaging Initiative, 2018 5, : : Alzheimer's and Dementia. 14, 5, p. 623-633 11 p.

研究成果: Article

16 引用 (Scopus)

Introduction of human Flt3-L and GM-CSF into humanized mice enhances the reconstitution and maturation of myeloid dendritic cells and the development of Foxp3+CD4+ T cells

Iwabuchi, R., Ikeno, S., Kobayashi-Ishihara, M., Takeyama, H., Ato, M., Tsunetsugu-Yokota, Y. & Terahara, K., 2018 5 28, : : Frontiers in Immunology. 9, MAY, 1042.

研究成果: Article

5 引用 (Scopus)

Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination

Ogawa, M., Matsuda, R., Takada, N., Tomokiyo, M., Yamamoto, S., Shizukusihi, S., Yamaji, T., Yoshikawa, Y., Yoshida, M., Tanida, I., Koike, M., Murai, M., Morita, H., Takeyama, H., Ryo, A., Guan, J. L., Yamamoto, M., Inoue, J. I., Yanagawa, T., Fukuda, M. および2人, Kawabe, H. & Ohnishi, M., 2018 8, : : Cellular Microbiology. 20, 8, e12846.

研究成果: Article

6 引用 (Scopus)
10 引用 (Scopus)

Protection of Coral Larvae from Thermally Induced Oxidative Stress by Redox Nanoparticles

Motone, K., Takagi, T., Aburaya, S., Aoki, W., Miura, N., Minakuchi, H., Takeyama, H., Nagasaki, Y., Shinzato, C. & Ueda, M., 2018 8 1, : : Marine Biotechnology. 20, 4, p. 542-548 7 p.

研究成果: Article

3 引用 (Scopus)

Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts

Mori, T., Cahn, J. K. B., Wilson, M. C., Meoded, R. A., Wiebach, V., Martinez, A. F. C., Helfrich, E. J. N., Albersmeier, A., Wibberg, D., Dätwyler, S., Keren, R., Lavy, A., Rückert, C., Ilan, M., Kalinowski, J., Matsunaga, S., Takeyama, H. & Piel, J., 2018 2 20, : : Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. 1718-1723 6 p.

研究成果: Article

17 引用 (Scopus)
2017

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines

Wada, Y., Nithichanon, A., Nobusawa, E., Moise, L., Martin, W. D., Yamamoto, N., Terahara, K., Hagiwara, H., Odagiri, T., Tashiro, M., Lertmemongkolchai, G., Takeyama, H., Groot, A. S. D., Ato, M. & Takahashi, Y., 2017 12 1, : : Scientific Reports. 7, 1, 1283.

研究成果: Article

15 引用 (Scopus)

Antimicrobial peptides extend lifespan in Drosophila

Loch, G., Zinke, I., Mori, T., Carrera, P., Schroer, J., Takeyama, H. & Hoch, M., 2017 5 1, : : PLoS One. 12, 5, e0176689.

研究成果: Article

13 引用 (Scopus)

Association between sensitivity of viral thymidine kinase-associated acyclovir-resistant herpes simplex virus type 1 and virulence

Omura, N., Fujii, H., Yoshikawa, T., Yamada, S., Harada, S., Inagaki, T., Shibamura, M., Takeyama, H. & Saijo, M., 2017 3 21, : : Virology Journal. 14, 1, 59.

研究成果: Article

5 引用 (Scopus)

Complete genome sequence of Photobacterium damselae subsp. piscicida strain OT-51443 isolated from yellowtail (Seriola quinqueradiata) in Japan

Aoki, T., Teru, Y., Morimoto, N., Kono, T., Sakai, M., Takano, T., Hawke, J. P., Fukuda, Y., Takeyama, H. & Hikima, J. I., 2017 1 1, : : Genome Announcements. 5, 21, e00404-17.

研究成果: Article

4 引用 (Scopus)

Exonuclease processivity of archaeal replicative DNA polymerase in association with PCNA is expedited by mismatches in DNA

Yoda, T., Tanabe, M., Tsuji, T., Yoda, T., Ishino, S., Shirai, T., Ishino, Y., Takeyama, H. & Nishida, H., 2017 3 16, : : Scientific Reports. 7, 44582.

研究成果: Article

2 引用 (Scopus)

Induction of lung CD8+ T cell responses by consecutive inoculations of a poly(I: C) influenza vaccine

Moriyama, M., Takeyama, H., Hasegawa, H. & Ichinohe, T., 2017, (Accepted/In press) : : Vaccine.

研究成果: Article

2 引用 (Scopus)
31 引用 (Scopus)

On-site Direct Detection of Astaxanthin from Salmon Fillet Using Raman Spectroscopy

Hikima, J. I., Ando, M., Hamaguchi, H. O., Sakai, M., Maita, M., Yazawa, K., Takeyama, H. & Aoki, T., 2017 4 1, : : Marine Biotechnology. 19, 2, p. 157-163 7 p.

研究成果: Article

1 引用 (Scopus)
2 引用 (Scopus)

Site-specific gene expression analysis using an automated tissue micro-dissection punching system

Yoda, T., Hosokawa, M., Takahashi, K., Sakanashi, C., Takeyama, H. & Kambara, H., 2017 12 1, : : Scientific Reports. 7, 1, 4325.

研究成果: Article

2 引用 (Scopus)

Transcriptome analysis of immune response against Vibrio harveyi infection in orange-spotted grouper (Epinephelus coioides)

Maekawa, S., Byadgi, O., Chen, Y. C., Aoki, T., Takeyama, H., Yoshida, T., Hikima, J. I., Sakai, M., Wang, P. C. & Chen, S. C., 2017 11 1, : : Fish and Shellfish Immunology. 70, p. 628-637 10 p.

研究成果: Article

10 引用 (Scopus)

Whole-genome sequence of Photobacterium damselae subsp. piscicida strain 91-197, isolated from hybrid striped bass (Morone sp.) in the United States

Teru, Y., Hikima, J. I., Kono, T., Sakai, M., Takano, T., Hawke, J. P., Takeyama, H. & Aoki, T., 2017 7 1, : : Genome Announcements. 5, 29, e00600-17.

研究成果: Article

2016

Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor

Brandstätter, O., Schanz, O., Vorac, J., König, J., Mori, T., Maruyama, T., Korkowski, M., Haarmann-Stemmann, T., Von Smolinski, D., Schultze, J. L., Abel, J., Esser, C., Takeyama, H., Weighardt, H. & Förster, I., 2016 5 17, : : Scientific Reports. 6, 26091.

研究成果: Article

25 引用 (Scopus)

Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus

Saga, R., Fujimoto, A., Watanabe, N., Matsuda, M., Hasegawa, M., Watashi, K., Aizaki, H., Nakamura, N., Tajima, S., Takasaki, T., Konishi, E., Kato, T., Kohara, M., Takeyama, H., Wakita, T. & Suzuki, R., 2016 6 27, : : Scientific reports. 6, 28688.

研究成果: Article

4 引用 (Scopus)

Characterization of a novel gene involved in cadmium accumulation screened from sponge-associated bacterial metagenome

Mori, T., Iwamoto, K., Wakaoji, S., Araie, H., Kohara, Y., Okamura, Y., Shiraiwa, Y. & Takeyama, H., 2016 2 1, : : Gene. 576, 2, p. 618-625 8 p.

研究成果: Article

7 引用 (Scopus)

Draft genome sequence of the fish pathogen Mycobacterium pseudoshottsii strain JCM15466, a species closely related to M. marinum

Hikima, J. I., Sakai, M., Aoki, T., Takeyama, H., Hawke, J., Mori, K., Tashiro, K. & Kuhara, S., 2016, : : Genome Announcements. 4, 1, e01630-15.

研究成果: Article

1 引用 (Scopus)

Falsirhodobacter sp. alg1 Harbors Single Homologs of Endo and Exo-Type Alginate Lyases Efficient for Alginate Depolymerization

Mori, T., Takahashi, M., Tanaka, R., Miyake, H., Shibata, T., Chow, S., Kuroda, K., Ueda, M. & Takeyama, H., 2016 5 1, : : PLoS One. 11, 5, e0155537.

研究成果: Article

7 引用 (Scopus)

Homeostatically maintained resting naive CD4+ T cells resist latent HIV reactivation

Tsunetsugu-Yokota, Y., Kobayahi-Ishihara, M., Wada, Y., Terahara, K., Takeyama, H., Kawana-Tachikawa, A., Tokunaga, K., Yamagishi, M., Martinez, J. P. & Meyerhans, A., 2016, : : Frontiers in Microbiology. 7, DEC, 1944.

研究成果: Article

10 引用 (Scopus)

The effect of mucoadhesive excipient on the nasal retention time of and the antibody responses induced by an intranasal influenza vaccine

Saito, S., Ainai, A., Suzuki, T., Harada, N., Ami, Y., Yuki, Y., Takeyama, H., Kiyono, H., Tsukada, H. & Hasegawa, H., 2016 2 24, : : Vaccine. 34, 9, p. 1201-1207 7 p.

研究成果: Article

11 引用 (Scopus)

The RNA- and TRIM25-binding domains of influenza virus NS1 protein are essential for suppression of NLRP3 inflammasomemediated interleukin-1β secretion

Moriyama, M., Chen, I. Y., Kawaguchi, A., Koshiba, T., Nagata, K., Takeyama, H., Hasegawa, H. & Ichinohe, T., 2016 4 1, : : Journal of Virology. 90, 8, p. 4105-4114 10 p.

研究成果: Article

39 引用 (Scopus)
2015

Analysis of bacterial xylose isomerase gene diversity using gene-targeted metagenomics

Nurdiani, D., Ito, M., Maruyama, T., Terahara, T., Mori, T., Ugawa, S. & Takeyama, H., 2015 8 1, : : Journal of Bioscience and Bioengineering. 120, 2, p. 174-180 7 p.

研究成果: Article

5 引用 (Scopus)

Droplet-based microfluidics for high-throughput screening of a metagenomic library for isolation of microbial enzymes

Hosokawa, M., Hoshino, Y., Nishikawa, Y., Hirose, T., Yoon, D. H., Mori, T., Sekiguchi, T., Shoji, S. & Takeyama, H., 2015 5 5, : : Biosensors and Bioelectronics. 67, p. 379-385 7 p.

研究成果: Article

53 引用 (Scopus)

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

Ueoka, R., Uria, A. R., Reiter, S., Mori, T., Karbaum, P., Peters, E. E., Helfrich, E. J. N., Morinaka, B. I., Gugger, M., Takeyama, H., Matsunaga, S. & Piel, J., 2015 9 20, : : Nature Chemical Biology. 11, 9, p. 705-712 8 p.

研究成果: Article

58 引用 (Scopus)

Monodisperse picoliter droplets for low-bias and contamination-free reactions in single-cell whole genome amplification

Nishikawa, Y., Hosokawa, M., Maruyama, T., Yamagishi, K., Mori, T. & Takeyama, H., 2015 9 21, : : PLoS One. 10, 9, e0138733.

研究成果: Article

24 引用 (Scopus)

Pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimp

Lai, H. C., Ng, T. H., Ando, M., Lee, C. T., Chen, I. T., Chuang, J. C., Mavichak, R., Chang, S. H., Yeh, M. D., Chiang, Y. A., Takeyama, H., Hamaguchi, H. O., Lo, C. F., Aoki, T. & Wang, H. C., 2015 12 1, : : Fish and Shellfish Immunology. 47, 2, p. 1006-1014 9 p.

研究成果: Article

80 引用 (Scopus)

Self-oriented immobilization of DNA polymerase tagged by titanium-binding peptide motif

Nishida, H., Kajisa, T., Miyazawa, Y., Tabuse, Y., Yoda, T., Takeyama, H., Kambara, H. & Sakata, T., 2015 1 20, : : Langmuir. 31, 2, p. 732-740 9 p.

研究成果: Article

10 引用 (Scopus)
2014

An environmental bacterial taxon with a large and distinct metabolic repertoire

Wilson, M. C., Mori, T., Rückert, C., Uria, A. R., Helf, M. J., Takada, K., Gernert, C., Steffens, U. A. E., Heycke, N., Schmitt, S., Rinke, C., Helfrich, E. J. N., Brachmann, A. O., Gurgui, C., Wakimoto, T., Kracht, M., Crüsemann, M., Hentschel, U., Abe, I., Matsunaga, S. および3人, Kalinowski, J., Takeyama, H. & Piel, J., 2014 1 1, : : Nature. 506, 7486, p. 58-62 5 p.

研究成果: Article

322 引用 (Scopus)

Draft genome sequence of Falsirhodobacter sp. strain alg1, an alginate-degrading bacterium isolated from fermented brown algae

Mori, T., Takahashi, M., Tanaka, R., Shibata, T., Kuroda, K., Ueda, M. & Takeyama, H., 2014, : : Genome Announcements. 2, 4, e00826-14.

研究成果: Article

3 引用 (Scopus)

Exacerbation of invasive candida albicans infection by commensal bacteria or a glycolipid through IFN- Produced in part by iNKT cells

Tarumoto, N., Kinjo, Y., Kitano, N., Sasai, D., Ueno, K., Okawara, A., Izawa, Y., Shinozaki, M., Watarai, H., Taniguchi, M., Takeyama, H., Maesaki, S., Shibuya, K. & Miyazaki, Y., 2014 3 1, : : Journal of Infectious Diseases. 209, 5, p. 799-810 12 p.

研究成果: Article

9 引用 (Scopus)

In situ detection of antibiotic amphotericin B produced in Streptomyces nodosus using Raman microspectroscopy

Miyaoka, R., Hosokawa, M., Ando, M., Mori, T., Hamaguchi, H. O. & Takeyama, H., 2014 5, : : Marine Drugs. 12, 5, p. 2827-2839 13 p.

研究成果: Article

10 引用 (Scopus)

Whole Genome Analyses of Marine Fish Pathogenic Isolate, Mycobacterium sp. 012931

Kurokawa, S., Kabayama, J., Hwang, S. D., Nho, S. W., Hikima, J. I., Jung, T. S., Kondo, H., Hirono, I., Takeyama, H., Mori, T. & Aoki, T., 2014 10, : : Marine Biotechnology. 16, 5, p. 572-579 8 p.

研究成果: Article

2 引用 (Scopus)