• 7884 引用
  • 44 h指数
20022019
Pureに変更を加えた場合、すぐここに表示されます。

研究成果 2002 2019

  • 7884 引用
  • 44 h指数
  • 91 Article
  • 11 Review article
  • 2 Chapter
フィルター
Article
2019
6 引用 (Scopus)

Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock

Uehara, T. N., Mizutani, Y., Kuwata, K., Hirota, T., Sato, A., Mizoi, J., Takao, S., Matsuo, H., Suzuki, T., Ito, S., Saito, A. N., Nishiwaki-Ohkawa, T., Yamaguchi-Shinozaki, K., Yoshimura, T., Kay, S. A., Itami, K., Kinoshita, T., Yamaguchi, J. & Nakamichi, N., 2019 1 1, : : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11528-11536 9 p.

研究成果: Article

公開
Casein Kinase I
Circadian Clocks
Post Translational Protein Processing
Arabidopsis
Proteomics
10 引用 (Scopus)

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

Oshima, T., Niwa, Y., Kuwata, K., Srivastava, A., Hyoda, T., Tsuchiya, Y., Kumagai, M., Tsuyuguchi, M., Tamaru, T., Sugiyama, A., Ono, N., Zolboot, N., Aikawa, Y., Oishi, S., Nonami, A., Arai, F., Hagihara, S., Yamaguchi, J., Tama, F., Kunisaki, Y. および6人, Yagita, K., Ikeda, M., Kinoshita, T., Kay, S. A., Itami, K. & Hirota, T., 2019 1 23, : : Science Advances. 5, 1, eaau9060.

研究成果: Article

公開
Circadian Rhythm
Circadian Clocks
Phosphotransferases
Growth
Neoplasms
2 引用 (Scopus)

Pd-Catalyzed Dearomative Three-Component Reaction of Bromoarenes with Diazo Compounds and Allylborates

Komatsuda, M., Kato, H., Muto, K. & Yamaguchi, J., 2019 1 1, : : ACS Catalysis. 9, 10, p. 8991-8995 5 p.

研究成果: Article

Diazomethane
Borates
Bromides
carbene
2 引用 (Scopus)

Pd-Catalyzed Denitrative Intramolecular C-H Arylation

Asahara, K. K., Okita, T., Saito, A. N., Muto, K., Nakao, Y. & Yamaguchi, J., 2019 6 21, : : Organic Letters. 21, 12, p. 4721-4724 4 p.

研究成果: Article

Bearings (structural)
Catalysis
linkages
catalysis
Substitution reactions
1 引用 (Scopus)

Structure–function study of a novel inhibitor of the casein kinase 1 family in Arabidopsis thaliana

Saito, A. N., Matsuo, H., Kuwata, K., Ono, A., Kinoshita, T., Yamaguchi, J. & Nakamichi, N., 2019 9 1, : : Plant Direct. 3, 9, e00172.

研究成果: Article

公開
Casein Kinase I
Arabidopsis
inhibitor
Arabidopsis thaliana
protein
2018
8 引用 (Scopus)

Decarbonylative aryl thioether synthesis by Ni catalysis

Ishitobi, K., Isshiki, R., Asahara, K. K., Lim, C., Muto, K. & Yamaguchi, J., 2018 1 1, : : Chemistry Letters. 47, 6, p. 756-759 4 p.

研究成果: Article

Sulfides
Catalysis
Nickel
Catalysts
Air
28 引用 (Scopus)
Organophosphorus Compounds
phosphine
esters
Esters
Phosphorus Compounds
6 引用 (Scopus)

Decarbonylative Methylation of Aromatic Esters by a Nickel Catalyst

Okita, T., Muto, K. & Yamaguchi, J., 2018 5 18, : : Organic Letters. 20, 10, p. 3132-3135 4 p.

研究成果: Article

methylation
Methylation
Nickel
esters
Esters
7 引用 (Scopus)

Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors

Ota, Y., Miyamura, S., Araki, M., Itoh, Y., Yasuda, S., Masuda, M., Taniguchi, T., Sowa, Y., Sakai, T., Itami, K., Yamaguchi, J. & Suzuki, T., 2018 2 1, : : Bioorganic and Medicinal Chemistry. 26, 3, p. 775-785 11 p.

研究成果: Article

Lysine
Cells
Tranylcypromine
Amination
Methylation
4 引用 (Scopus)

Dibenzofuran Synthesis: Decarbonylative Intramolecular C−H Arylation of Aromatic Esters

Okita, T., Komatsuda, M., Saito, A. N., Hisada, T., Takahara, T. T., Nakayama, K. P., Isshiki, R., Takise, R., Muto, K. & Yamaguchi, J., 2018 7 1, : : Asian Journal of Organic Chemistry. 7, 7, p. 1358-1361 4 p.

研究成果: Article

Esters
Bearings (structural)
Ethers
Palladium
Functional groups
6 引用 (Scopus)

Modular synthesis of heptaarylindole

Suzuki, S., Asako, T., Itami, K. & Yamaguchi, J., 2018 1 1, : : Organic and Biomolecular Chemistry. 16, 20, p. 3771-3776 6 p.

研究成果: Article

Cycloaddition Reaction
Electrons
Regioselectivity
Acids
Cycloaddition
Biological Products
Artificial intelligence
8 引用 (Scopus)

Pd-Catalyzed Dearomative Allylation of Benzyl Phosphates

Komatsuda, M., Muto, K. & Yamaguchi, J., 2018 7 20, : : Organic Letters. 20, 14, p. 4354-4357 4 p.

研究成果: Article

Allylation
phosphates
Phosphates
Borates
Palladium
1 引用 (Scopus)

Pd-Catalyzed Decarbonylative C-H Coupling of Azoles and Aromatic Esters

Matsushita, K., Takise, R., Hisada, T., Suzuki, S., Isshiki, R., Itami, K., Muto, K. & Yamaguchi, J., 2018 1 1, (Accepted/In press) : : Chemistry - An Asian Journal.

研究成果: Article

Azoles
Esters
Palladium
Catalysis
Substrates
Thiophenes
Alkynes
Cycloaddition
isoquinoline
2017
12 引用 (Scopus)

Catalytic α-Arylation of Ketones with Heteroaromatic Esters

Isshiki, R., Takise, R., Itami, K., Muto, K. & Yamaguchi, J., 2017 9 26, (Accepted/In press) : : Synlett.

研究成果: Article

Ketones
Esters
Carbonyl compounds
Ligands
Costs
54 引用 (Scopus)

Decarbonylative Diaryl Ether Synthesis by Pd and Ni Catalysis

Takise, R., Isshiki, R., Muto, K., Itami, K. & Yamaguchi, J., 2017 3 8, : : Journal of the American Chemical Society. 139, 9, p. 3340-3343 4 p.

研究成果: Article

Ethers
Phenols
Palladium
Catalysis
Ether
33 引用 (Scopus)

Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Okita, T., Kumazawa, K., Takise, R., Muto, K., Itami, K. & Yamaguchi, J., 2017, : : Chemistry Letters. 46, 2, p. 218-220 3 p.

研究成果: Article

Halogens
Alkynes
Palladium
Esters
11 引用 (Scopus)
Hydrosilylation
Carbon
Ligands
Silanes
Regioselectivity
10 引用 (Scopus)

Synthesis of multiply arylated pyridines

Asako, T., Hayashi, W., Amaike, K., Suzuki, S., Itami, K., Muto, K. & Yamaguchi, J., 2017 1 31, (Accepted/In press) : : Tetrahedron.

研究成果: Article

Pyridines
Cycloaddition
Cycloaddition Reaction
cinnamic acid
11 引用 (Scopus)

Synthesis of Octaaryl Naphthalenes and Anthracenes with Different Substituents

Suzuki, S., Itami, K. & Yamaguchi, J., 2017 11 20, : : Angewandte Chemie - International Edition. 56, 47, p. 15010-15013 4 p.

研究成果: Article

Anthracenes
Naphthalenes
Anthracene
Naphthalene
Oxides
9 引用 (Scopus)

Theoretical Elucidation of Potential Enantioselectivity in a Pd-Catalyzed Aromatic C-H Coupling Reaction

Nishimoto, Y., Kondo, H., Yamaguchi, K., Yokogawa, D., Yamaguchi, J., Itami, K. & Irle, S., 2017 5 5, : : Journal of Organic Chemistry. 82, 9, p. 4900-4906 7 p.

研究成果: Article

Enantioselectivity
Catalysts
Stereoselectivity
Ligands
Acids
3 引用 (Scopus)

Thiazole-Based σ1 Receptor Ligands: Diversity by Late-Stage C−H Arylation of Thiazoles, Structure–Affinity and Selectivity Relationships, and Molecular Interactions

Kokornaczyk, A. K., Schepmann, D., Yamaguchi, J., Itami, K., Laurini, E., Fermeglia, M., Pricl, S. & Wünsch, B., 2017, : : ChemMedChem. 12, 13, p. 1070-1080 11 p.

研究成果: Article

Thiazoles
Molecular interactions
Ligands
Thiophenes
Derivatives
27 引用 (Scopus)
Aromatic compounds
Transition metals
Catalysts
Molecules
2016
19 引用 (Scopus)

C-H activation enables a rapid structure-activity relationship study of arylcyclopropyl amines for potent and selective LSD1 inhibitors

Miyamura, S., Araki, M., Ota, Y., Itoh, Y., Yasuda, S., Masuda, M., Taniguchi, T., Sowa, Y., Sakai, T., Suzuki, T., Itami, K. & Yamaguchi, J., 2016, : : Organic and Biomolecular Chemistry. 14, 36, p. 8576-8585 10 p.

研究成果: Article

Structure-Activity Relationship
inhibitors
Amines
amines
Chemical activation
41 引用 (Scopus)

Cyanation of Phenol Derivatives with Aminoacetonitriles by Nickel Catalysis

Takise, R., Itami, K. & Yamaguchi, J., 2016 9 2, : : Organic Letters. 18, 17, p. 4428-4431 4 p.

研究成果: Article

Aminoacetonitrile
Phenol
Nickel
Catalysis
phenols
7 引用 (Scopus)

Microwave-assisted regioselective direct C-H arylation of thiazole derivatives leading to increased σ1 receptor affinity

Kokornaczyk, A., Schepmann, D., Yamaguchi, J., Itami, K. & Wünsch, B., 2016 2 1, : : MedChemComm. 7, 2, p. 327-331 5 p.

研究成果: Article

Thiazoles
Microwaves
Derivatives
Thiophenes
Microwave irradiation
27 引用 (Scopus)

Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids

Muto, K., Hatakeyama, T., Itami, K. & Yamaguchi, J., 2016 10 7, : : Organic Letters. 18, 19, p. 5106-5109 4 p.

研究成果: Article

cross coupling
Palladium
Nickel
palladium
acids
9 引用 (Scopus)

Syntheses of Biologically Active 2-Arylcyclopropylamines

Miyamura, S., Itami, K. & Yamaguchi, J., 2016 9 21, (Accepted/In press) : : Synthesis (Germany).

研究成果: Article

Cinnamates
Cyclization
Styrene
Cyclopropanes
Diketopiperazines
29 引用 (Scopus)
Antibiotics
Anti-Bacterial Agents
Cycloaddition Reaction
Nickel
Cycloaddition
41 引用 (Scopus)

The AMOR Arabinogalactan Sugar Chain Induces Pollen-Tube Competency to Respond to Ovular Guidance

Mizukami, A. G., Inatsugi, R., Jiao, J., Kotake, T., Kuwata, K., Ootani, K., Okuda, S., Sankaranarayanan, S., Sato, Y., Maruyama, D., Iwai, H., Garénaux, E., Sato, C., Kitajima, K., Tsumuraya, Y., Mori, H., Yamaguchi, J., Itami, K., Sasaki, N. & Higashiyama, T., 2016 4 25, : : Current Biology. 26, 8, p. 1091-1097 7 p.

研究成果: Article

Pollen Tube
arabinogalactans
pollen tubes
Sugars
sugars
2015
26 引用 (Scopus)

C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock

Oshima, T., Yamanaka, I., Kumar, A., Yamaguchi, J., Nishiwaki-Ohkawa, T., Muto, K., Kawamura, R., Hirota, T., Yagita, K., Irle, S., Kay, S. A., Yoshimura, T. & Itami, K., 2015 6 1, : : Angewandte Chemie - International Edition. 54, 24, p. 7193-7197 5 p.

研究成果: Article

Cryptochromes
Clocks
Chemical activation
Derivatives
Molecules
60 引用 (Scopus)
Alkenylation
Imidazoles
Nickel
Catalysis
Chemical activation
68 引用 (Scopus)

Concise syntheses of dictyodendrins A and F by a sequential C-H functionalization strategy

Yamaguchi, A. D., Chepiga, K. M., Yamaguchi, J., Itami, K. & Davies, H. M. L., 2015 1 21, : : Journal of the American Chemical Society. 137, 2, p. 644-647 4 p.

研究成果: Article

Rhodium
Cross Reactions
Biological Products
dictyodendrin A
dictyodendrins F
132 引用 (Scopus)

Decarbonylative organoboron cross-coupling of esters by nickel catalysis

Muto, K., Yamaguchi, J., Musaev, D. G. & Itami, K., 2015 6 29, : : Nature Communications. 6, 7508.

研究成果: Article

cross coupling
Nickel
Catalysis
catalysis
esters
60 引用 (Scopus)

Ni-Catalyzed α-arylation of esters and amides with phenol derivatives

Koch, E., Takise, R., Studer, A., Yamaguchi, J. & Itami, K., 2015 1 18, : : Chemical Communications. 51, 5, p. 855-857 3 p.

研究成果: Article

Phenol
Amides
Phenols
Esters
Nickel
51 引用 (Scopus)

Stereodivergent synthesis of arylcyclopropylamines by sequential C-H borylation and Suzuki-Miyaura coupling

Miyamura, S., Araki, M., Suzuki, T., Yamaguchi, J. & Itami, K., 2015 1 12, : : Angewandte Chemie - International Edition. 54, 3, p. 846-851 6 p.

研究成果: Article

Bearings (structural)
Carbon
Iridium
Atmosphere
Isomers
8 引用 (Scopus)

Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists

Junker, A., Kokornaczyk, A. K., Zweemer, A. J. M., Frehland, B., Schepmann, D., Yamaguchi, J., Itami, K., Faust, A., Hermann, S., Wagner, S., Schäfers, M., Koch, M., Weiss, C., Heitman, L. H., Kopka, K. & Wünsch, B., 2015, : : Organic and Biomolecular Chemistry. 13, 8, p. 2407-2422 16 p.

研究成果: Article

CCR2 Receptors
CCR5 Receptors
Structure-Activity Relationship
affinity
Lead compounds
76 引用 (Scopus)
Benzene
Benzene Derivatives
Agrochemicals
Chemical compounds
Cycloaddition
2014
11 引用 (Scopus)

2,4- and 2,5-disubstituted arylthiazoles: Rapid synthesis by C-H coupling and biological evaluation

Lohrey, L., Uehara, T. N., Tani, S., Yamaguchi, J., Humpf, H. U. & Itami, K., 2014, : : European Journal of Organic Chemistry. 2014, 16, p. 3387-3394 8 p.

研究成果: Article

antibiotics
bacteria
Bacteria
Anti-Bacterial Agents
congeners
45 引用 (Scopus)

Branch-selective allylic C-H carboxylation of terminal alkenes by pd/sox catalyst

Kondo, H., Yu, F., Yamaguchi, J., Liu, G. & Itami, K., 2014 8 15, : : Organic Letters. 16, 16, p. 4212-4215 4 p.

研究成果: Article

sulfoxide
carboxylation
Carboxylation
Alkenes
alkenes
7 引用 (Scopus)

Diverse modifications of the 4-methylphenyl moiety of TAK-779 by late-stage Suzuki-Miyaura cross-coupling

Junker, A., Schepmann, D., Yamaguchi, J., Itami, K., Faust, A., Kopka, K., Wagner, S. & Wünsch, B., 2014 1 7, : : Organic and Biomolecular Chemistry. 12, 1, p. 177-186 10 p.

研究成果: Article

Chemokine Receptors
cross coupling
Lead compounds
affinity
Cross Reactions
100 引用 (Scopus)

Key mechanistic features of Ni-catalyzed C-H/C-O biaryl coupling of azoles and naphthalen-2-yl pivalates

Xu, H., Muto, K., Yamaguchi, J., Zhao, C., Itami, K. & Musaev, D. G., 2014 10 22, : : Journal of the American Chemical Society. 136, 42, p. 14834-14844 11 p.

研究成果: Article

Benzoxazoles
Azoles
Chemical activation
Quinazolines
Gadiformes
18 引用 (Scopus)

Late-stage C-H coupling enables rapid identification of HDAC inhibitors: Synthesis and evaluation of NCH-31 analogues

Sekizawa, H., Amaike, K., Itoh, Y., Suzuki, T., Itami, K. & Yamaguchi, J., 2014 5 8, : : ACS Medicinal Chemistry Letters. 5, 5, p. 582-586 5 p.

研究成果: Article

Histone Deacetylase Inhibitors
Derivatives
Molecules
Testing
2-aminothiazole
17 引用 (Scopus)

Manganese-catalyzed intermolecular C-H/C-H coupling of carbonyls and heteroarenes

Hattori, K., Ziadi, A., Itami, K. & Yamaguchi, J., 2014 4 21, : : Chemical Communications. 50, 31, p. 4105-4107 3 p.

研究成果: Article

Manganese
Carboxylic Acids
Carboxylic acids
Oxidants
108 引用 (Scopus)

Nickel-catalyzed α-arylation of ketones with phenol derivatives

Takise, R., Muto, K., Yamaguchi, J. & Itami, K., 2014 6 23, : : Angewandte Chemie - International Edition. 53, 26, p. 6791-6794 4 p.

研究成果: Article

Thiophenes
Carbamates
Thiophene
Phenol
Nickel
141 引用 (Scopus)

Programmed synthesis of arylthiazoles through sequential C-H couplings

Tani, S., Uehara, T. N., Yamaguchi, J. & Itami, K., 2014 1, : : Chemical Science. 5, 1, p. 123-135 13 p.

研究成果: Article

Thiazoles
Palladium
Nickel
Substitution reactions
Catalysts
76 引用 (Scopus)

β-selective C-H arylation of pyrroles leading to concise syntheses of lamellarins C and I

Ueda, K., Amaike, K., Maceiczyk, R. M., Itami, K. & Yamaguchi, J., 2014 9 24, : : Journal of the American Chemical Society. 136, 38, p. 13226-13232 7 p.

研究成果: Article

Regioselectivity
Alkaloids
Pyrroles
Rhodium
Drug products
2013
76 引用 (Scopus)

Aromatic C-H coupling with hindered arylboronic acids by Pd/Fe dual catalysts

Yamaguchi, K., Kondo, H., Yamaguchi, J. & Itami, K., 2013 9, : : Chemical Science. 4, 9, p. 3753-3757 5 p.

研究成果: Article

sulfoxide
Styrene
Alkenes
Oxidants
Ligands
92 引用 (Scopus)

C-H alkenylation of azoles with enols and esters by nickel catalysis

Meng, L., Kamada, Y., Muto, K., Yamaguchi, J. & Itami, K., 2013 9 16, : : Angewandte Chemie - International Edition. 52, 38, p. 10048-10051 4 p.

研究成果: Article

Alkenylation
Azoles
Nickel
Catalysis
Esters