年別の研究成果
年別の研究成果
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2023
HOXB7 induces STAT3-mediated transformation and lung metastasis in immortalized mammary gland NMuMG cells
Azuma, K., Sakamoto, M., Katayama, S., Matsui, A., Nakamichi, K., Goshima, N., Watanabe, S., Nakayama, J. & Semba, K., 2023, (Accepted/In press) In: Genes to Cells.研究成果 › 査読
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2022
Identification of two cancer stem cell-like populations in triple-negative breast cancer xenografts
Nakayama, J., Matsunaga, H., Arikawa, K., Yoda, T., Hosokawa, M., Takeyama, H., Yamamoto, Y. & Semba, K., 2022, In: DMM Disease Models and Mechanisms. 15, 6, dmm049538.研究成果 › 査読
Open Access4 被引用数 (Scopus) -
Isolation of Reporter Cells That Respond to Vitamin A and/or D Using a piggyBac Transposon Promoter-Trapping Vector System
Ishikawa, K., Tamamura, S., Takahashi, N., Takagi, M., Semba, K. & Watanabe, S., 2022 8月, In: International journal of molecular sciences. 23, 16, 9366.研究成果 › 査読
Open Access -
Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells
Aoyama, M., Ishikawa, K., Nemoto, S., Hirano, H., Watanabe, N., Osada, H., Watanabe, S. & Semba, K., 2022 12月, In: Journal of Biological Chemistry. 298, 12, 102635.研究成果 › 査読
Open Access -
Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein
Yamamoto, M., Gohda, J., Kobayashi, A., Tomita, K., Hirayama, Y., Koshikawa, N., Seiki, M., Semba, K., Akiyama, T., Kawaguchi, Y. & Inoue, J. I., 2022 8月, In: mBio. 13, 4研究成果 › 査読
Open Access9 被引用数 (Scopus) -
Metastatic profiling of HER2-positive breast cancer cell lines in xenograft models
Han, Y., Azuma, K., Watanabe, S., Semba, K. & Nakayama, J., 2022 6月, In: Clinical and Experimental Metastasis. 39, 3, p. 467-477 11 p.研究成果 › 査読
1 被引用数 (Scopus) -
Prediction of Resistance Mutations Against Upcoming Anaplastic Lymphoma Kinase Inhibitors
Doi, Y., Tagaya, H., Noge, A. & Semba, K., 2022 11月, In: Targeted Oncology. 17, 6, p. 695-707 13 p.研究成果 › 査読
1 被引用数 (Scopus) -
2021
A screening system for identifying interacting proteins using biomolecular fluorescence complementation and transposon gene trap
Miyakura, H., Fukuda, M., Enomoto, H., Ishikawa, K., Watanabe, S. & Semba, K., 2021 5月, In: PloS one. 16, 5 May, e0251240.研究成果 › 査読
Open Access -
Epithelial cells remove precancerous cells by cell competition via MHC class I–LILRB3 interaction
Ayukawa, S., Kamoshita, N., Nakayama, J., Teramoto, R., Pishesha, N., Ohba, K., Sato, N., Kozawa, K., Abe, H., Semba, K., Goda, N., Fujita, Y. & Maruyama, T., 2021 11月, In: Nature Immunology. 22, 11, p. 1391-1402 12 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Establishment of reporter cells that respond to glucocorticoids by a transposon-mediated promoter-trapping system
Ishikawa, K., Tamamura, S., Semba, K. & Watanabe, S., 2021 7月 1, In: European Journal of Pharmaceutical Sciences. 162, 105819.研究成果 › 査読
Open Access1 被引用数 (Scopus) -
The in vivo selection method in breast cancer metastasis
Nakayama, J., Han, Y., Kuroiwa, Y., Azuma, K., Yamamoto, Y. & Semba, K., 2021 2月 2, In: International journal of molecular sciences. 22, 4, p. 1-19 19 p., 1886.研究成果 › 査読
Open Access6 被引用数 (Scopus) -
2020
Establishment and characterization of highly osteolytic luminal breast cancer cell lines by intracaudal arterial injection
Han, Y., Nakayama, J., Hayashi, Y., Jeong, S., Futakuchi, M., Ito, E., Watanabe, S. & Semba, K., 2020 2月 1, In: Genes to Cells. 25, 2, p. 111-123 13 p.研究成果 › 査読
Open Access15 被引用数 (Scopus) -
Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1
Kuga, K., Kusakari, Y., Uesugi, K., Semba, K., Urashima, T., Akaike, T. & Minamisawa, S., 2020 4月, In: PloS one. 15, 4, e0231905.研究成果: Article › 査読
Open Access19 被引用数 (Scopus) -
Generation of Rat Monoclonal Antibodies Specific for Human Stromal Cell-Derived Factor-2
Tanaka, M., Shiota, M., Koyama, M., Nakayama, J., Yashiro, M., Semba, K. & Goda, N., 2020 2月, In: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 39, 1, p. 23-26 4 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
High sensitivity in vivo imaging of cancer metastasis using a near-infrared luciferin analogue seMpai
Nakayama, J., Saito, R., Hayashi, Y., Kitada, N., Tamaki, S., Han, Y., Semba, K. & Maki, S. A., 2020 11月 1, In: International journal of molecular sciences. 21, 21, p. 1-8 8 p., 7896.研究成果 › 査読
Open Access12 被引用数 (Scopus) -
Proliferative classification of intracranially injected HER2-positive breast cancer cell lines
Kuroiwa, Y., Nakayama, J., Adachi, C., Inoue, T., Watanabe, S. & Semba, K., 2020 7月, In: Cancers. 12, 7, p. 1-18 18 p., 1811.研究成果 › 査読
Open Access9 被引用数 (Scopus) -
Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity
Nakamura, T., Hashikawa, C., Okabe, K., Yokote, Y., Chirifu, M., Toma-Fukai, S., Nakamura, N., Matsuo, M., Kamikariya, M., Okamoto, Y., Gohda, J., Akiyama, T., Semba, K., Ikemizu, S., Otsuka, M., Inoue, J. I. & Yamagata, Y., 2020 12月 1, In: Scientific reports. 10, 1, 5152.研究成果 › 査読
Open Access3 被引用数 (Scopus) -
The anticoagulant nafamostat potently inhibits SARS-CoV-2 S protein-mediated fusion in a cell fusion assay system and viral infection in vitro in a cell-type-dependent manner
Yamamoto, M., Kiso, M., Sakai-Tagawa, Y., Iwatsuki-Horimoto, K., Imai, M., Takeda, M., Kinoshita, N., Ohmagari, N., Gohda, J., Semba, K., Matsuda, Z., Kawaguchi, Y., Kawaoka, Y. & Inoue, J. I., 2020 6月, In: Viruses. 12, 6, v12060629.研究成果 › 査読
Open Access159 被引用数 (Scopus) -
2019
A method of producing genetically manipulated mouse mammary gland
Tagaya, H., Ishikawa, K., Hosokawa, Y., Kobayashi, S., Ueoka, Y., Shimada, M., Ohashi, Y., Mikami, H., Yamamoto, M., Ihara, T., Kumazawa, K., Sugihara, K., Goshima, N., Watanabe, S. & Semba, K., 2019 1月 5, In: Breast cancer research : BCR. 21, 1, p. 1 1 p.研究成果 › 査読
Open Access3 被引用数 (Scopus) -
Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells
Maekawa, M., Hiyoshi, H., Nakayama, J., Kido, K., Sawasaki, T., Semba, K., Kubota, E., Joh, T. & Higashiyama, S., 2019 9月 3, In: Biochemical and Biophysical Research Communications. 516, 4, p. 1116-1122 7 p.研究成果 › 査読
Open Access4 被引用数 (Scopus) -
Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells
Murakami, A., Maekawa, M., Kawai, K., Nakayama, J., Araki, N., Semba, K., Taguchi, T., Kamei, Y., Takada, Y. & Higashiyama, S., 2019 2月, In: Cancer Science. 110, 2, p. 650-661 12 p.研究成果 › 査読
Open Access27 被引用数 (Scopus) -
Genetic manipulation of the mammary gland and potential applications
Tagaya, H., Semba, K. & Ishikawa, K., 2019, In: Oncotarget. 10, 42, p. 4253-4254 2 p.研究成果 › 査読
Open Access1 被引用数 (Scopus) -
SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9
Tanigawa, K., Maekawa, M., Kiyoi, T., Nakayama, J., Kitazawa, R., Kitazawa, S., Semba, K., Taguchi, T., Akita, S., Yoshida, M., Ishimaru, K., Watanabe, Y. & Higashiyama, S., 2019 10月, In: Journal of Cellular Physiology. 234, 10, p. 17280-17294 15 p.研究成果 › 査読
Open Access19 被引用数 (Scopus) -
TRAF6 maintains mammary stem cells and promotes pregnancy-induced mammary epithelial cell expansion
Yamamoto, M., Abe, C., Wakinaga, S., Sakane, K., Yumiketa, Y., Taguchi, Y., Matsumura, T., Ishikawa, K., Fujimoto, J., Semba, K., Miyauchi, M., Akiyama, T. & Inoue, J. I., 2019 12月 1, In: Communications Biology. 2, 1, 292.研究成果 › 査読
Open Access9 被引用数 (Scopus) -
2018
A highly sensitive trap vector system for isolating reporter cells and identification of responsive genes
Ishikawa, K., Kobayashi, Y., Wakabayashi, Y., Watanabe, S. & Semba, K., 2018 12月 31, In: Biology Methods and Protocols. 3, 1, bpy003.研究成果 › 査読
Open Access4 被引用数 (Scopus) -
Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines
Namatame, N., Tamaki, N., Yoshizawa, Y., Okamura, M., Nishimura, Y., Yamazaki, K., Tanaka, M., Nakamura, T., Semba, K., Yamori, T., Yaguchi, S. I. & Dan, S., 2018 10月 1, In: Oncotarget. 9, 80, p. 35141-35161 21 p.研究成果 › 査読
Open Access11 被引用数 (Scopus) -
PHLDA1, another PHLDA family protein that inhibits Akt
Chen, Y., Takikawa, M., Tsutsumi, S., Yamaguchi, Y., Okabe, A., Shimada, M., Kawase, T., Sada, A., Ezawa, I., Takano, Y., Nagata, K., Suzuki, Y., Semba, K., Aburatani, H. & Ohki, R., 2018 11月, In: Cancer Science. 109, 11, p. 3532-3542 11 p.研究成果 › 査読
Open Access28 被引用数 (Scopus) -
2017
An in vivo screening system to identify tumorigenic genes
Ihara, T., Hosokawa, Y., Kumazawa, K., Ishikawa, K., Fujimoto, J., Yamamoto, M., Muramkami, T., Goshima, N., Ito, E., Watanabe, S. & Semba, K., 2017 4月 6, In: Oncogene. 36, 14, p. 2023-2029 7 p.研究成果 › 査読
9 被引用数 (Scopus) -
Comparative analysis of gene regulatory networks of highly metastatic breast cancer cells established by orthotopic transplantation and intra-circulation injection
Nakayama, J., Ito, E., Fujimoto, J., Watanabe, S. & Semba, K., 2017 2月, In: International journal of oncology. 50, 2, p. 497-504 8 p.研究成果 › 査読
Open Access13 被引用数 (Scopus) -
Construction and evaluation of pH-sensitive immunoliposomes for enhanced delivery of anticancer drug to ErbB2 over-expressing breast cancer cells
Li, T., Amari, T., Semba, K., Yamamoto, T. & Takeoka, S., 2017 4月 1, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 3, p. 1219-1227 9 p.研究成果 › 査読
31 被引用数 (Scopus) -
Construction of a novel cell-based assay for the evaluation of anti-EGFR drug efficacy against EGFR mutation
Hoshi, H., Hiyama, G., Ishikawa, K., Inageda, K., Fujimoto, J., Wakamatsu, A., Togashi, T., Kawamura, Y., Takahashi, N., Higa, A., Goshima, N., Semba, K., Watanabe, S. & Takagi, M., 2017 1月, In: Oncology Reports. 37, 1, p. 66-76 11 p.研究成果 › 査読
Open Access11 被引用数 (Scopus) -
Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
Matsudaira, T., Mukai, K., Noguchi, T., Hasegawa, J., Hatta, T., Iemura, S. I., Natsume, T., Miyamura, N., Nishina, H., Nakayama, J., Semba, K., Tomita, T., Murata, S., Arai, H. & Taguchi, T., 2017 12月 1, In: Nature communications. 8, 1, 1246.研究成果 › 査読
Open Access25 被引用数 (Scopus) -
Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer
Yamamoto, M., Sakane, K., Tominaga, K., Gotoh, N., Niwa, T., Kikuchi, Y., Tada, K., Goshima, N., Semba, K. & Inoue, J. I., 2017 6月, In: Cancer Science. 108, 6, p. 1210-1222 13 p.研究成果 › 査読
Open Access16 被引用数 (Scopus) -
The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB
Okita, Y., Kimura, M., Xie, R., Chen, C., Shen, L. T. W., Kojima, Y., Suzuki, H., Muratani, M., Saitoh, M., Semba, K., Heldin, C. H. & Kato, M., 2017 4月 11, In: Science Signaling. 10, 474研究成果 › 査読
40 被引用数 (Scopus) -
Type i neuregulin1α is a novel local mediator to suppress hepatic gluconeogenesis in mice
Arai, T., Ono, Y., Arimura, Y., Sayama, K., Suzuki, T., Shinjo, S., Kanai, M., Abe, S. I., Semba, K. & Goda, N., 2017 2月 20, In: Scientific reports. 7, 42959.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
2016
Hepatocyte nuclear factor 1 beta induces transformation and epithelial-to-mesenchymal transition
Matsui, A., Fujimoto, J., Ishikawa, K., Ito, E., Goshima, N., Watanabe, S. & Semba, K., 2016 4月 1, In: FEBS Letters. 590, 8, p. 1211-1221 11 p.研究成果 › 査読
19 被引用数 (Scopus) -
IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis
Asano, Y., Kawase, T., Okabe, A., Tsutsumi, S., Ichikawa, H., Tatebe, S., Kitabayashi, I., Tashiro, F., Namiki, H., Kondo, T., Semba, K., Aburatani, H., Taya, Y., Nakagama, H. & Ohki, R., 2016 1月 12, In: Scientific reports. 6, 19174.研究成果 › 査読
Open Access29 被引用数 (Scopus) -
Novel p53 target gene FUCA1 encodes a fucosidase and regulates growth and survival of cancer cells
Ezawa, I., Sawai, Y., Kawase, T., Okabe, A., Tsutsumi, S., Ichikawa, H., Kobayashi, Y., Tashiro, F., Namiki, H., Kondo, T., Semba, K., Aburatani, H., Taya, Y., Nakagama, H. & Ohki, R., 2016 6月 1, In: Cancer Science. 107, 6, p. 734-745 12 p.研究成果 › 査読
Open Access32 被引用数 (Scopus) -
δNp63α induces quiescence and downregulates the BRCA1 pathway in estrogen receptor-positive luminal breast cancer cell line MCF7 but not in other breast cancer cell lines
Amin, R., Morita-Fujimura, Y., Tawarayama, H., Semba, K., Chiba, N., Fukumoto, M. & Ikawa, S., 2016 4月 1, In: Molecular Oncology. 10, 4, p. 575-593 19 p.研究成果 › 査読
Open Access18 被引用数 (Scopus) -
2015
Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial-to-mesenchymal transition and disruption of mammary acinar structures
Doi, A., Ishikawa, K., Shibata, N., Ito, E., Fujimoto, J., Yamamoto, M., Shiga, H., Mochizuki, H., Kawamura, Y., Goshima, N., Semba, K. & Watanabe, S., 2015 2月 1, In: Molecular Oncology. 9, 2, p. 355-364 10 p.研究成果 › 査読
23 被引用数 (Scopus) -
The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia
Yamauchi, H., Matsumaru, T., Morita, T., Ishikawa, S., Maenaka, K., Takigawa, I., Semba, K., Kon, S. & Fujita, Y., 2015 10月 20, In: Scientific reports. 5, 15336.研究成果 › 査読
Open Access15 被引用数 (Scopus) -
Tropomodulin 1 expression driven by NF-κB enhances breast cancer growth
Ito-Kureha, T., Koshikawa, N., Yamamoto, M., Semba, K., Yamaguchi, N., Yamamoto, T., Seiki, M. & Inoue, J. I., 2015 1月 1, In: Cancer Research. 75, 1, p. 62-72 11 p.研究成果 › 査読
25 被引用数 (Scopus) -
2013
Cell growth control by stable Rbg2/Gir2 complex formation under amino acid starvation
Ishikawa, K., Ito, K., Inoue, J. I. & Semba, K., 2013 10月, In: Genes to Cells. 18, 10, p. 859-872 14 p.研究成果 › 査読
7 被引用数 (Scopus) -
Gene amplification: Mechanisms and involvement in cancer
Matsui, A., Ihara, T., Suda, H., Mikami, H. & Semba, K., 2013 12月 1, In: Biomolecular Concepts. 4, 6, p. 567-582 16 p.研究成果 › 査読
65 被引用数 (Scopus) -
Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes
Shirakihara, T., Kawasaki, T., Fukagawa, A., Semba, K., Sakai, R., Miyazono, K., Miyazawa, K. & Saitoh, M., 2013 9月, In: Cancer Science. 104, 9, p. 1189-1197 9 p.研究成果 › 査読
41 被引用数 (Scopus) -
NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype
Yamamoto, M., Taguchi, Y., Ito-Kureha, T., Semba, K., Yamaguchi, N. & Inoue, J. I., 2013, In: Nature communications. 4, 2299.研究成果 › 査読
138 被引用数 (Scopus) -
Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Yoshikawa, S., Kukimoto-Niino, M., Parker, L., Handa, N., Terada, T., Fujimoto, T., Terazawa, Y., Wakiyama, M., Sato, M., Sano, S., Kobayashi, T., Tanaka, T., Chen, L., Liu, Z. J., Wang, B. C., Shirouzu, M., Kawa, S., Semba, K., Yamamoto, T. & Yokoyama, S., 2013 1月 3, In: Oncogene. 32, 1, p. 27-38 12 p.研究成果 › 査読
90 被引用数 (Scopus) -
2012
CXCL17 Expression by Tumor Cells Recruits CD11b+Gr1highF4/80- Cells and Promotes Tumor Progression
Matsui, A., Yokoo, H., Negishi, Y., Endo-Takahashi, Y., Chun, N. A. L., Kadouchi, I., Suzuki, R., Maruyama, K., Aramaki, Y., Semba, K., Kobayashi, E., Takahashi, M. & Murakami, T., 2012 8月 29, In: PloS one. 7, 8, e44080.研究成果 › 査読
58 被引用数 (Scopus) -
Expression screening of 17q12-21 amplicon reveals GRB7 as an ERBB2-dependent oncogene
Saito, M., Kato, Y., Ito, E., Fujimoto, J., Ishikawa, K., Doi, A., Kumazawa, K., Matsui, A., Takebe, S., Ishida, T., Azuma, S., Mochizuki, H., Kawamura, Y., Yanagisawa, Y., Honma, R., Imai, J. I., Ohbayashi, H., Goshima, N., Semba, K. & Watanabe, S., 2012 6月 12, In: FEBS Letters. 586, 12, p. 1708-1714 7 p.研究成果 › 査読
Open Access18 被引用数 (Scopus) -
Potential anti-tumor effect of IFN-λ2 (IL-28A) against human lung cancer cells
Tezuka, Y., Endo, S., Matsui, A., Sato, A., Saito, K., Semba, K., Takahashi, M. & Murakami, T., 2012 12月, In: Lung Cancer. 78, 3, p. 185-192 8 p.研究成果 › 査読
34 被引用数 (Scopus)