澤村 直哉

上級研究員(研究院教授)

  • 2102 引用
  • 21 h指数
1994 …2020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 2102 引用
  • 21 h指数
  • 38 Article
  • 1 Conference contribution
  • 1 Comment/debate
  • 1 Short survey
フィルター
Article
2020

Mammalian cell cultivation using nutrients extracted from microalgae

Okamoto, Y., Haraguchi, Y., Sawamura, N., Asahi, T. & Shimizu, T., 2020 3 1, : : Biotechnology Progress. 36, 2, e2941.

研究成果: Article

2019
公開

Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease

Imai, Y., Inoshita, T., Meng, H., Shiba-Fukushima, K., Hara, K. Y., Sawamura, N. & Hattori, N., 2019 12 1, : : Communications Biology. 2, 1, 424.

研究成果: Article

公開
4 引用 (Scopus)
1 引用 (Scopus)
2018

Antioxidant activity of Ge-132, a synthetic organic germanium, on cultured mammalian cells

Wada, T., Hanyu, T., Nozaki, K., Kataoka, K., Kawatani, T., Asahi, T. & Sawamura, N., 2018 1 1, : : Biological and Pharmaceutical Bulletin. 41, 5, p. 749-753 5 p.

研究成果: Article

8 引用 (Scopus)

The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity

Sawamura, N., Yamada, M., Fujiwara, M., Yamada, H., Hayashi, H., Takagi, N. & Asahi, T., 2018 12 1, : : Scientific Reports. 8, 1, 2459.

研究成果: Article

6 引用 (Scopus)
2017
5 引用 (Scopus)
2016
8 引用 (Scopus)
7 引用 (Scopus)

Ohgata, the single Drosophila ortholog of human cereblon, regulates insulin signaling-dependent organismic growth

Wakabayashi, S., Sawamura, N., Voelzmann, A., Broemer, M., Asahi, T. & Hoch, M., 2016 11 25, : : Journal of Biological Chemistry. 291, 48, p. 25120-25132 13 p.

研究成果: Article

1 引用 (Scopus)
2015
14 引用 (Scopus)
2014

A label-free electrical assay of fibrous amyloid β based on semiconductor biosensing

Hideshima, S., Kobayashi, M., Wada, T., Kuroiwa, S., Nakanishi, T., Sawamura, N., Asahi, T. & Osaka, T., 2014 4 4, : : Chemical Communications. 50, 26, p. 3476-3479 4 p.

研究成果: Article

12 引用 (Scopus)
13 引用 (Scopus)
2013
公開
15 引用 (Scopus)
2008

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly

Sawamura, N., Ando, T., Maruyama, Y., Fujimuro, M., Mochizuki, H., Honjo, K., Shimoda, M., Toda, H., Sawamura-Yamamoto, T., Makuch, L. A., Hayashi, A., Ishizuka, K., Cascella, N. G., Kamiya, A., Ishida, N., Tomoda, T., Hai, T., Furukubo-Tokunaga, K. & Sawa, A., 2008 12, : : Molecular Psychiatry. 13, 12, p. 1138-1148 11 p.

研究成果: Article

77 引用 (Scopus)

The fruitfly Drosophila melanogaster: A promising model to explore molecular psychiatry

Sawamura, N., Ishida, N., Tomoda, T., Hai, T., Furukubo-Tokunaga, K. & Sawa, A., 2008 12 1, : : Molecular Psychiatry. 13, 12, 1 p.

研究成果: Article

1 引用 (Scopus)
2006

Primate disrupted-in-schizophrenia-1 (DISC1): High divergence of a gene for major mental illnesses in recent evolutionary history

Bord, L., Wheeler, J., Paek, M., Saleh, M., Lyons-Warren, A., Ross, C. A., Sawamura, N. & Sawa, A., 2006 11 1, : : Neuroscience Research. 56, 3, p. 286-293 8 p.

研究成果: Article

26 引用 (Scopus)
2005
92 引用 (Scopus)

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

Kamiya, A., Kubo, K. I., Tomoda, T., Takaki, M., Youn, R., Ozeki, Y., Sawamura, N., Park, U., Kudo, C., Okawa, M., Ross, C. A., Hatten, M. E., Nakajima, K. & Sawa, A., 2005 12 1, : : Nature Cell Biology. 7, 12, p. 1067-1078 12 p.

研究成果: Article

415 引用 (Scopus)

Disrupted-In-Schizophrenia-1 (DISC1): A promising lead in molecular analyzes of schizophrenia

Sawa, A., Sawamura, N. & Balkissoon, R., 2005 9, : : Clinical Neuroscience Research. 5, 1 SPEC. ISS., p. 23-30 8 p.

研究成果: Article

1 引用 (Scopus)
2004

Modulation of Amyloid Precursor Protein Cleavage by Cellular Sphingolipids

Sawamura, N., Ko, M., Yu, W., Zou, K., Hanada, K., Suzuki, T., Gong, J. S., Yanagisawa, K. & Michikawa, M., 2004 3 19, : : Journal of Biological Chemistry. 279, 12, p. 11984-11991 8 p.

研究成果: Article

71 引用 (Scopus)
2003

Amyloid β-protein (Aβ)1-40 protects neurons from damage induced by Aβ1-42 in culture and in rat brain

Zou, K., Kim, D., Kakio, A., Byun, K., Gong, J. S., Kim, J., Kim, M., Sawamura, N., Nishimoto, S. I., Matsuzaki, K., Lee, B., Yanagisawa, K. & Michikawa, M., 2003 11 1, : : Journal of neurochemistry. 87, 3, p. 609-619 11 p.

研究成果: Article

114 引用 (Scopus)
27 引用 (Scopus)
2002

Amyloid β-protein affects cholesterol metabolism in cultured neurons: Implications for pivotal role of cholesterol in the amyloid cascade

Gong, J. S., Sawamura, N., Zou, K., Sakai, J., Yanagisawa, K. & Michikawa, M., 2002 11 2, : : Journal of Neuroscience Research. 70, 3, p. 438-446 9 p.

研究成果: Article

46 引用 (Scopus)

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice.

Gong, J. S., Kobayashi, M., Hayashi, H., Zou, K., Sawamura, N., Fujita, S. C., Yanagisawa, K. & Michikawa, M., 2002 8 16, : : The Journal of biological chemistry. 277, 33, p. 29919-29926 8 p.

研究成果: Article

公開
155 引用 (Scopus)

Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons

Fan, Q. W., Yu, W., Gong, J. S., Zou, K., Sawamura, N., Senda, T., Yanagisawa, K. & Michikawa, M., 2002, : : Journal of neurochemistry. 80, 1, p. 178-190 13 p.

研究成果: Article

94 引用 (Scopus)
2001

A novel action of Alzheimer's amyloid β-protein (Aβ): Oligomeric Aβ promotes lipid release

Michikawa, M., Gong, J. S., Fan, Q. W., Sawamura, N. & Yanagisawa, K., 2001 9 15, : : Journal of Neuroscience. 21, 18, p. 7226-7235 10 p.

研究成果: Article

公開
131 引用 (Scopus)

Site-specific Phosphorylation of Tau Accompanied by Activation of Mitogen-activated Protein Kinase (MAPK) in Brains of Niemann-Pick Type C Mice

Sawamura, N., Gong, J. S., Garver, W. S., Heidenreich, R. A., Ninomiya, H., Ohno, K., Yanagisawa, K. & Michikawa, M., 2001 3 30, : : Journal of Biological Chemistry. 276, 13, p. 10314-10319 6 p.

研究成果: Article

92 引用 (Scopus)
2000

Mutant presenilin 2 transgenic mice: A large increase in the levels of Aβ342 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin

Sawamura, N., Morishima-Kawashima, M., Waki, H., Kobayashi, K., Kuramochi, T., Frosch, M. P., Ding, K., Ito, M., Kim, T. W., Tanzi, R. E., Oyama, F., Tabira, T., Ando, S. & Ihara, Y., 2000 9 8, : : Journal of Biological Chemistry. 275, 36, p. 27901-27908 8 p.

研究成果: Article

74 引用 (Scopus)
1998

Mutant presenilin 2 transgenic mouse: Effect on an age-dependent increase of amyloid β-protein 42 in the brain

Oyama, F., Sawamura, N., Kobayashi, K., Morishima-Kawashima, M., Kuramochi, T., Ito, M., Tomita, T., Maruyama, K., Saido, T. C., Iwatsubo, T., Capell, A., Walter, J., Grünberg, J., Ueyama, Y., Haass, C. & Ihara, Y., 1998 7 1, : : Journal of neurochemistry. 71, 1, p. 313-322 10 p.

研究成果: Article

82 引用 (Scopus)
1997

Amyloid β protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease

Tamaoka, A., Sawamura, N., Fukushima, T., Shoji, S., Matsubara, E., Shoji, M., Hirai, S., Furiya, Y., Endoh, R. & Mori, H., 1997 5 1, : : Journal of the Neurological Sciences. 148, 1, p. 41-45 5 p.

研究成果: Article

115 引用 (Scopus)

Characterization of amyloid β protein species in cerebral amyloid angiopathy of a squirrel monkey by immunocytochemistry and enzyme-linked immunosorbent assay

Sawamura, N., Tamaoka, A., Shoji, S. N. I., Koo, E. H., Walker, L. C. & Mori, H., 1997 8 1, : : Brain Research. 764, 1-2, p. 225-229 5 p.

研究成果: Article

12 引用 (Scopus)

Deposition of amyloid β protein (Aβ) subtypes [Aβ40 and Aβ42(43)] in canine senile plaques and cerebral amyoloid angiopathy

Nakamura, S., Tamaoka, A., Sawamura, N., Kiatipattanasakul, W., Nakayama, H., Shoji, S., Yoshikawa, Y. & Doi, K., 1997 10 1, : : Acta Neuropathologica. 94, 4, p. 323-328 6 p.

研究成果: Article

26 引用 (Scopus)
1996

Amyloid β protein in plasma from patients with sporadic Alzheimer' s disease

Tamaoka, A., Fukushima, T., Sawamura, N., Ishikawa, K., Oguni, E., Komatsuzaki, Y. & Shoji, S., 1996 9 15, : : Journal of the Neurological Sciences. 141, 1-2, p. 65-68 4 p.

研究成果: Article

134 引用 (Scopus)
1995

Amyloid β protein 1-42/43 (Aβ 1-42/43) in cerebellar diffuse plaques: enzyme-linked immunosorbent assay and immunocytochemical study

Tamaoka, A., Sawamura, N., Odaka, A., Suzuki, N., Mizusawa, H., Shoji, S. & Mori, H., 1995 5 8, : : Brain Research. 679, 1, p. 151-156 6 p.

研究成果: Article

63 引用 (Scopus)

Carboxyl end-specific monoclonal antibodies to amyloid β protein (Aβ) subtypes (Aβ40 and Aβ42(43)) differentiate Aβ in senile plaques and amyloid angiopathy in brains of aged cynomolgus monkeys

Nakamura, S., Tamaoka, A., Sawamura, N., Shoji, S., Nakayama, H., Ono, F., Sakakibara, I., Yoshikawa, Y., Mori, H., Goto, N. & Doi, K., 1995 12 8, : : Neuroscience Letters. 201, 2, p. 151-154 4 p.

研究成果: Article

31 引用 (Scopus)
1994

Biochemical evidence for the long-tail form (Aβ1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of alzheimer′s disease

Tamaoka, A., Kondo, T., Odaka, A., Sahara, N., Sawamura, N., Ozawa, K., Suzuki, N., Shoji, S. & Mori, H., 1994 11 30, : : Biochemical and Biophysical Research Communications. 205, 1, p. 834-842 9 p.

研究成果: Article

101 引用 (Scopus)