加藤 尚志

研究成果

年別の研究成果 1985 1996 1997 1998 2020

• 7838 被引用数
• 46 h-index
• 163 Article
• 4 Letter
• 4 Review article
• 3 Comment/debate
• 1 その他
  • 1 Editorial

年別の研究成果

年別の研究成果

検索結果

• 1985

  Production of erythropoietin‐like activity by human renal and hepatic carcinomas in cell culture

  Okabe, T., Urabe, A., Kato, T., Chiba, S. & Takaku, F., 1985 5月 1, In: Cancer. 55, 9, p. 1918-1923 6 p.

  研究成果: Article › 査読

  • Human Activities 100%
  • Cell Culture Techniques 75%
  • Carcinoma 65%
  • Kidney 53%
  • Nude Mice 52%
  21 被引用数 (Scopus)
• 1986

  Binding of sex steroid to oviduct cytosol of the newt, Cynops pyrrhogaster ensicauda

  Kato, T., Kikuyama, S. & Noumura, T., 1986, In: Proceedings of the Japan Academy Series B: Physical and Biological Sciences. 62, 5, p. 153-156 4 p.

  研究成果: Article › 査読
  2 被引用数 (Scopus)

• Unique pattern of gene expression in the erythroid precursor cells

  Mishina, Y., Kato, T. & Urabe, A., 1986, In: Development Growth and Differentiation. 28, 1, p. 1-6 6 p.

  研究成果: Article › 査読
  3 被引用数 (Scopus)
• 1988

  Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells

  Takeuchi, M., Takasaki, S., Miyazaki, H., Kato, T., Hoshi, S., Kochibe, N. & Kobata, A., 1988, In: Journal of Biological Chemistry. 263, 8, p. 3657-3663 7 p.

  研究成果: Article › 査読

  • Erythropoietin 100%
  • Asparagine 87%
  • Culture Media 75%
  • Cricetulus 75%
  • Sugars 68%
  288 被引用数 (Scopus)

• Production of monoclonal antibodies against human erythropoietin and their use in the purification of human urinary erythropoietin

  Hiroshi Miyazaki, M., Hiroyuki Kozutsumi, K., Takashi Kato, K., Sakuo Hoshi, H., Setsuko Tamura, T., Mamoru Kubota, K. & Takamoto Suzuki, S., 1988 10月 26, In: Journal of Immunological Methods. 113, 2, p. 261-267 7 p.

  研究成果: Article › 査読

  • Erythropoietin 100%
  • Monoclonal Antibodies 69%
  • Competitive Binding 20%
  • Aplastic Anaemia 19%
  • Hybridomas 18%
  11 被引用数 (Scopus)
• 1993

  Growth factor‐induced process formation of megakaryocytes derived from CFU‐MK

  Inoue, H., Ishii, H., Tsutsumi, M., Takahashi, N., Sato, M., Shimada, Y., Kato, T., Sudo, T. & Miyazaki, H., 1993 10月, In: British Journal of Haematology. 85, 2, p. 260-269 10 p.

  研究成果: Article › 査読
  9 被引用数 (Scopus)

• Structure and Expression of Novel Protein-Tyrosine Kinases, EMB and EMT, in Hematopoietic Cells

  Yamada, N., Kawakami, Y., Kimura, H., Fukamachi, H., Baier, G., Altman, A., Kato, T., Inagaki, Y. & Kawakami, T., 1993 1月 1, In: Biochemical and Biophysical Research Communications. 192, 1, p. 231-240 10 p.

  研究成果: Article › 査読

  • Mast Cells 100%
  • Tyrosine 93%
  • Protein-Tyrosine Kinases 93%
  • emb protein-tyrosine kinase 88%
  • src Homology Domains 82%
  115 被引用数 (Scopus)
• 1994

  Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by FcεRI cross-linking

  Fukamachi, H., Yamada, N., Miura, T., Kato, T., Ishikawa, M., Gulbins, E., Altman, A., Kawakami, Y. & Kawakami, T., 1994 1月 15, In: Journal of Immunology. 152, 2, p. 642-652 11 p.

  研究成果: Article › 査読

  • Helix-Turn-Helix Motifs 100%
  • src Homology Domains 74%
  • Tyrosine 56%
  • Protein-Tyrosine Kinases 55%
  • Phosphorylation 26%
  46 被引用数 (Scopus)

• Molecular cloning and chromosomal localization of the human thrombopoietin gene

  Sohma, Y., Akahori, H., Seki, N., Hori, T. A., Ogami, K., Kato, T., Shimada, Y., Kawamura, K. & Miyazaki, H., 1994 10月 10, In: FEBS Letters. 353, 1, p. 57-61 5 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Molecular Cloning 86%
  • Southern Blotting 61%
  • Probe 45%
  • Complementary DNA 38%
  239 被引用数 (Scopus)

• Molecular cloning and chromosomal localization of the human thrombopoietin gene Yoshiaki Sohma a, Hiromichi Akahori a, Naohiko Seki b,c, Tada-aki Hori b, Kinya Ogami a

  Kato, T., 1994, In: FEBS Letters. 353, 1, p. 57-61 5 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Molecular Cloning 86%
  • Southern Blotting 61%
  • Probe 45%
  • Complementary DNA 38%
• 1995

  A simple and quantitative liquid culture system to measure megakaryocyte growth using highly purified CSU-MK

  Miyazaki, H., Horie, K., Shimada, Y., Kokubo, A., Maeda, E., Inoue, H. & Kato, T., 1995 1月 1, In: Experimental Hematology. 23, 11, p. 1224-1228 5 p.

  研究成果: Article › 査読

  • Megakaryocytes 100%
  • serotonin drug combination creatinine sulfate 54%
  • Growth 41%
  • Interleukin-3 32%
  • Stem Cells 30%
  13 被引用数 (Scopus)

• Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin

  Matsumura, I., Kanakura, Y., Kato, T., Ikeda, H., Ishikawa, J., Horikawa, Y., Hashimoto, K., Moriyama, Y., Tsujimura, T., Nishiura, T., Miyazaki, H. & Matsuzawa, Y., 1995 7月 15, In: Blood. 86, 2, p. 703-709 7 p.

  研究成果: Article › 査読

  Open Access

  • Thrombopoietin 100%
  • Proliferative 98%
  • Growth Factor 87%
  • Acute Myeloid Leukemia 70%
  • Colony Stimulating Factor 55%
  88 被引用数 (Scopus)

• Megakaryocyte growth and development factor: Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy- induced thrombocytopenia

  Nichol, J. L., Hokom, M. M., Hornkohl, A., Sheridan, W. P., Ohashi, H., Kato, T., Yue Sheng Li, S. L., Bartley, T. D., Choi, E., Bogenberger, J., Skrine, J. D., Knudten, A., Chen, J., Trail, G., Sleeman, L., Cole, S., Grampp, G. & Hunt, P., 1995, In: Journal of Clinical Investigation. 95, 6, p. 2973-2978 6 p.

  研究成果: Article › 査読

  Open Access

  • Thrombopoietin 100%
  • Thrombocytopenia 69%
  • Statistical Factor Analysis 65%
  • Drug Therapy 43%
  • Serum 33%
  193 被引用数 (Scopus)

• Production of thrombopoietin (TPO) by rat hepatocytes and hepatoma cell lines

  Shimada, Y., Kato, T., Ogami, K., Horie, K., Kokubo, A., Kudo, Y., Maeda, E., Sohma, Y., Akahori, H., Kawamura, K. & Miyazaki, H., 1995 12月 1, In: Experimental Hematology. 23, 13, p. 1388-1396 9 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Hepatocytes 62%
  • Hepatocellular Carcinoma 59%
  • Cell Line 43%
  • Culture Media 12%
  86 被引用数 (Scopus)

• Purification and characterization of thrombopoietin

  Kato, T., Ogami, K., Shimada, Y., Iwamatsu, A., Sohma, Y., Akahori, H., Horie, K., Kokubo, A., Kudo, Y., Maeda, E., Kobayashi, K., Ohashi, H., Ozawa, T., Inoue, H., Kawamura, K. & Miyazaki, H., 1995 7月, In: Journal of biochemistry. 118, 1, p. 229-236 8 p.

  研究成果: Article › 査読

  • Thrombopoietic 100%
  • Thrombopoietin 92%
  • Purification 46%
  • Plasma 42%
  • Complementary DNA 23%
  248 被引用数 (Scopus)

• Recombinant human megakaryocyte growth and development factor (rhumgdf), a ligand for c‐mpl, produces functional human platelets in vitro

  Choi, E. S., Hokom, M., Bartley, T., Li, YS. S., Nichol, J. L., Skrine, J., Knudten, A., Chen, J., Hornkohl, A., Grampp, G., Sleeman, L., Cole, S., Trail, G., Hunt, P., Ohashi, H. & Kato, T., 1995, In: STEM CELLS. 13, 3, p. 317-322 6 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Blood Platelets 57%
  • Ligands 52%
  • Megakaryocytes 44%
  • In Vitro Techniques 32%
  91 被引用数 (Scopus)

• Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors

  Kobayashi, M., Laver, J. H., Kato, T., Miyazaki, H. & Ogawa, M., 1995 10月 1, In: Blood. 86, 7, p. 2494-2499 6 p.

  研究成果: Article › 査読

  Open Access

  • Colony Stimulating Factor 100%
  • Erythropoietin 95%
  • Thrombopoietin 90%
  • Cord 82%
  • Stem Cell Factor 40%
  159 被引用数 (Scopus)

• Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets

  Miyakawa, Y., Oda, A., Druker, B. J., Kato, T., Miyazaki, H., Handa, M. & Ikeda, Y., 1995 7月 1, In: Blood. 86, 1, p. 23-27 5 p.

  研究成果: Article › 査読

  Open Access

  • Janus Kinase 2 100%
  • Thrombopoietin 96%
  • Tyrosine 65%
  • Blood Platelets 55%
  • Phosphorylation 49%
  133 被引用数 (Scopus)

• The sequence of a rat cDNA encoding thrombopoietin

  Ogami, K., Shimada, Y., Sohma, Y., Akahori, H., Kato, T., Kawamura, K. & Miyazaki, H., 1995 6月 9, In: Gene. 158, 2, p. 309-310 2 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Complementary DNA 59%
  • Gene Library 26%
  • Clone Cells 19%
  • Amino Acids 17%
  36 被引用数 (Scopus)

• Thrombopoietin induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in a human thrombopoietin-dependent cell line

  Yamada, M., Komatsu, N., Okada, K., Kato, T., Miyazaki, H. & Miura, Y., 1995, In: Biochemical and Biophysical Research Communications. 217, 1, p. 230-237 8 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Mitogen-Activated Protein Kinases 73%
  • Tyrosine 68%
  • Phosphorylation 51%
  • Cell Line 43%
  46 被引用数 (Scopus)
• 1996

  Activity of the ligand for c-mpl, thrombopoietin, in early haemopoiesis

  Itoh, R., Katayama, N., Kato, T., Mahmud, N., Masuya, M., Ohishi, K., Minami, N., Miyazaki, H. & Shiku, H., 1996 1月 1, In: British Journal of Haematology. 94, 2, p. 228-235 8 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Interleukin-3 33%
  • Stem Cell Factor 6%
  • Fluorouracil 5%
  • Serum 5%
  28 被引用数 (Scopus)

• A highly sensitive and specific ellsa for measuring thrombopoietin in human serum

  Tahara, T., Usuki, K., Sato, H., Ohashi, H., Monta, H., Taiimura, H., Mivazaki', H. & Kato, T., 1996, In: Experimental Hematology. 24, 9, p. 1068 1 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Serum 33%
  • Enzymes 23%
  • Platelet Count 11%
  • Essential Thrombocythemia 8%

• Analysis of functional domains of the human tpo receptor encoded by C-MPL

  Takatoku, M., Komateu, N., Shimizu, R., Kato, T., Miyazakis, H. & Miuräï, Y., 1996 12月 1, In: Experimental Hematology. 24, 9, 1 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • anti-c antibody 41%
  • Clone Cells 39%
  • Thrombopoietin Receptors 37%
  • Platelet Factor 4 33%

• A sensitive sandwich ELISA for measuring thrombopoietin in human serum: Serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders

  Tahara, T., Usuki, K., Sato, H., Ohashi, H., Morita, H., Tsumura, H., Matsumoto, A., Miyazaki, H., Urabe, A. & Kato, T., 1996 1月 1, In: British Journal of Haematology. 93, 4, p. 783-788 6 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Enzyme-Linked Immunosorbent Assay 52%
  • Healthy Volunteers 49%
  • Serum 33%
  • Essential Thrombocythemia 24%
  197 被引用数 (Scopus)

• Circulating endogenous thrombopoietin, interleukin-3, interleukin-6 and interleukin-11 levels in patients undergoing allogeneic bone marrow transplantation

  Ishida, A., Miyakawa, Y., Tanosaki, R., Wakui, M., Ueno, H., Watanabe, R., Awaya, N., Tahara, T., Kato, T., Miyazaki, H., Oda, A., Kizaki, M., Okamoto, S. & Ikeda, Y., 1996 12月, In: International Journal of Hematology. 65, 1, p. 61-69 9 p.

  研究成果: Article › 査読

  Open Access

  • Interleukin-11 100%
  • Thrombopoietin 95%
  • Interleukin-3 83%
  • Homologous Transplantation 79%
  • Bone Marrow Transplantation 72%
  14 被引用数 (Scopus)

• Circulating thrombopoietin level in chronic immune thrombocytopenic purpura

  Kosugi, S., Kurata, Y., Tomiyama, Y., Tahara, T., Kato, T., Tadokoro, S., Shiraga, M., Honda, S., Kanakura, Y. & Matsuzawa, Y., 1996 1月 1, In: British Journal of Haematology. 93, 3, p. 704-706 3 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Idiopathic Thrombocytopenic Purpura 88%
  • Aplastic Anaemia 25%
  • Platelet Count 20%
  • Thrombocytopenia 19%
  169 被引用数 (Scopus)

• Coexpression of thrombopoietin and c-mpl genes in human acute myeloblastic leukemia cells

  Matsumura, I., Kanakura, Y., Ikeda, H., Ishikawa, J., Yoshida, H., Horikawa, Y., Nishiura, T., Tahara, T., Kato, T., Miyazaki, H. & Matsuzawa, Y., 1996 1月, In: Leukemia. 10, 1, p. 91-94 4 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Acute Myeloid Leukemia 70%
  • Genes 29%
  • Leukemia 20%
  • Intercellular Signaling Peptides and Proteins 13%
  27 被引用数 (Scopus)

• Cyclic change of cytokines in a patient with cyclic thrombocytopenia

  Kimura, F., Nakamura, Y., Sato, K., Wakimoto, N., Kato, T., Tahara, T., Yamada, M., Nagata, N. & Motoyoshi, K., 1996, In: British Journal of Haematology. 94, 1, p. 171-174 4 p.

  研究成果: Article › 査読

  • Cyclic Thrombocytopenia 100%
  • Platelet Count 48%
  • Cytokines 31%
  • Erythropoietin 26%
  • Blood Platelets 19%
  29 被引用数 (Scopus)

• Effect of recombinant human thrombopoietin in nonhuman primates with chemotherapy-induced thrombocytopenia

  Akahori, H., Shibuya, K., Obuchi, M., Nishizawa, Y., Tsuji, A., Kabaya, K., Kusaka, M., Ohashi, H., Tsumura, H., Kato, T. & Miyazaki, H., 1996 1月 1, In: British Journal of Haematology. 94, 4, p. 722-728 7 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Thrombocytopenia 69%
  • Primates 69%
  • Drug Therapy 43%
  • Haplorhini 19%
  50 被引用数 (Scopus)

• Effects of pegylated recombinant human megakaryocyte growth and development factor on thrombocytopenia induced by a new myelosuppressive chemotherapy regimen in mice

  Akahori, H., Shibuya, K., Ozai, M., Ida, M., Kabaya, K., Kato, T. & Miyazaki, H., 1996 11月, In: STEM CELLS. 14, 6, p. 678-689 12 p.

  研究成果: Article › 査読

  • polyethylene glycol-recombinant human megakaryocyte growth and development factor 100%
  • Thrombocytopenia 50%
  • Drug Therapy 31%
  • Thrombopoietin 31%
  • Thrombopoiesis 22%
  30 被引用数 (Scopus)

• Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO

  Komatsu, N., Kunitama, M., Yamada, M., Hagiwara, T., Kato, T., Miyazaki, H., Eguchi, M., Yamamoto, M. & Miura, Y., 1996 6月 1, In: Blood. 87, 11, p. 4552-4560 9 p.

  研究成果: Article › 査読

  Open Access

  • Erythropoietin 100%
  • Thrombopoietin 94%
  • Cell Line 41%
  • Tyrosine 32%
  • Colony Stimulating Factor 26%
  87 被引用数 (Scopus)

• Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation

  Morita, H., Tahara, T., Matsumoto, A., Kato, T., Miyazaki, H. & Ohashi, H., 1996 10月 21, In: FEBS Letters. 395, 2-3, p. 228-234 7 p.

  研究成果: Article › 査読

  • human MPL protein 100%
  • Signalling Molecule 62%
  • Tyrosine 45%
  • Phosphorylation 34%
  • Thrombopoietin 33%
  60 被引用数 (Scopus)

• GpIIb/IIIa⁺ subpopulation of rat megakaryocyte progenitor cells exhibits high responsiveness to human thrombopoietin

  Kato, T., Horie, K., Hagiwara, T., Maeda, E., Tsumura, H., Ohashi, H. & Miyazaki, H., 1996 9月 3, In: Experimental Hematology. 24, 10, p. 1209-1214 6 p.

  研究成果: Article › 査読

  • Megakaryocyte Progenitor Cells 100%
  • Thrombopoietin 87%
  • Megakaryocytes 78%
  • Interleukin-3 25%
  • Stem Cells 19%
  19 被引用数 (Scopus)

• Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets

  Tanaka, S., Kurabuchi, S., Mochida, H., Kato, T., Takahashi, S., Watanabe, T. & Nakayama, K., 1996, In: Archives of Histology and Cytology. 59, 3, p. 261-271 11 p.

  研究成果: Article › 査読

  Open Access

  • Proprotein Convertase 2 100%
  • Islets of Langerhans 59%
  • Pancreatic Polypeptide 54%
  • Glucagon 41%
  • Somatostatin 41%
  48 被引用数 (Scopus)

• Improvement of thrombocytopenia following bone marrow transplantation by pegylated recombinant human megakaryocyte growth and development factor in mice

  Kabaya, K., Shibuya, K., Torii, Y., Nitta, Y., Ida, M., Akahori, H., Kato, T., Kusaka, M. & Miyazaki, H., 1996 12月 1, In: Bone Marrow Transplantation. 18, 6, p. 1035-1041 7 p.

  研究成果: Article › 査読

  • polyethylene glycol-recombinant human megakaryocyte growth and development factor 100%
  • Bone Marrow Transplantation 55%
  • Thrombocytopenia 50%
  • Megakaryocyte Progenitor Cells 23%
  • Blood Platelets 18%
  16 被引用数 (Scopus)

• In vivo effects of pegylated recombinant human megakaryocyte growth and development factor on hematopoiesis in normal mice

  Kabaya, K., Akahori, H., Shibuya, K., Nitta, Y., Ida, M., Kusaka, M., Kato, T. & Miyazaki, H., 1996 11月, In: STEM CELLS. 14, 6, p. 651-660 10 p.

  研究成果: Article › 査読

  • polyethylene glycol-recombinant human megakaryocyte growth and development factor 100%
  • Hematopoiesis 58%
  • Bone Marrow 23%
  • Megakaryocytes 19%
  • Mean Platelet Volume 14%
  36 被引用数 (Scopus)

• Plasma thrombopoietin concentrations in patients with acquired aplastic anemia

  Kojima, S., Matsuyama, T., Kodera, Y., Tahara, T. & Kato, T., 1996, In: Experimental Hematology. 24, 9, p. 1063 1 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Aplastic Anaemia 89%
  • Immunosuppressive Agents 12%
  • Megakaryocytes 8%
  • Hematopoiesis 8%

• Protein characteristics of thrombopoietin

  Kato, T., 1996, In: STEM CELLS. 14, SUPPL. 1, p. 139-147 9 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Proteins 27%
  • Disulfides 9%
  • Hepatocytes 7%
  • Molecular Weight 7%
  7 被引用数 (Scopus)

• Regulation of serum thrombopoietin levels by platelets and megakaryocytes in patients with aplastic anaemia and idiopathic thrombocytopenic purpura

  Ichikawa, N., Ishida, F., Shimodaira, S., Tahara, T., Kato, T. & Kitano, K., 1996, In: Thrombosis and Haemostasis. 76, 2, p. 156-160 5 p.

  研究成果: Article › 査読

  • Inosine Triphosphate 100%
  • Thrombopoietin 92%
  • Megakaryocytes 82%
  • Aplastic Anaemia 82%
  • Idiopathic Thrombocytopenic Purpura 81%
  92 被引用数 (Scopus)

• Serum thrombopoietin (c-Mpl ligand) levels in patients with liver cirrhosis

  Shimodaira, S., Ishida, F., Ichikawa, N., Tahara, T., Kato, T., Kodaira, H., Ito, T., Tanaka, E., Sodeyama, T., Kiyosawa, K. & Kitano, K., 1996 10月, In: Thrombosis and Haemostasis. 76, 4, p. 545-548 4 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Liver Cirrhosis 68%
  • Serum 33%
  • Platelet Count 23%
  • Partial Thromboplastin Time 9%
  56 被引用数 (Scopus)

• Serum thrombopoietin (TPO) levels in patients with amegakaryocytic thrombocytopenia are much higher than those with immune thrombocytopenic purpura

  Mukai, H. Y., Kojima, H., Todokoro, K., Tahara, T., Kato, T., Hasegawa, Y., Kobayashi, T., Ninomiya, H., Nagasawa, T. & Abe, T., 1996 11月, In: Thrombosis and Haemostasis. 76, 5, p. 675-678 4 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Idiopathic Thrombocytopenic Purpura 88%
  • Thrombocytopenia 69%
  • Serum 33%
  • Platelet Count 30%
  63 被引用数 (Scopus)

• Serum thrombopoietin and plasma glycocalicin concentrations as useful diagnostic markers in thrombocytopenic disorders

  Kunishima, S., Tahara, T., Kato, T., Kobayashi, S., Saito, H. & Naoe, T., 1996, In: European Journal of Haematology. 57, 1, p. 68-71 4 p.

  研究成果: Article › 査読

  • glycocalicin 100%
  • Thrombopoietin 75%
  • Idiopathic Thrombocytopenic Purpura 44%
  • Aplastic Anaemia 33%
  • Myelodysplastic Syndromes 31%
  36 被引用数 (Scopus)

• Serum thrombopoietin level in various hematological diseases

  Usuki, K., Tahara, T., Iki, S., Endo, M., Osawa, M., Kitazume, K., Kato, T., Miyazaki, H. & Urabe, A., 1996 9月, In: STEM CELLS. 14, 5, p. 558-565 8 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Hematologic Diseases 86%
  • Serum 33%
  • Platelet Count 30%
  • Liver Cirrhosis 19%
  54 被引用数 (Scopus)

• Serum thrombopoietin level in various hematological diseases

  Urabe, A., Usuki, K., Iki, S., Endo, M., Tahara, T., Kato, T. & Mivazaki, H., 1996 12月 1, In: Experimental Hematology. 24, 9, 1 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Hematologic Diseases 86%
  • Platelet Count 35%
  • Serum 33%
  • Leukemia 22%

• Soluble thrombopoietin receptor (Mpl) and granulocyte colony-stimulating factor receptor directly stimulate proliferation of primitive hematopoietic progenitors of mice in synergy with steel factor or the ligand for Flt3/Flk2

  Ku, H., Hirayama, F., Kato, T., Miyazaki, H., Aritomi, M., Ota, Y., D'Andrea, A. D., Lyman, S. D. & Ogawa, M., 1996 12月 1, In: Blood. 88, 11, p. 4124-4131 8 p.

  研究成果: Article › 査読

  Open Access

  • Granulocyte Colony-Stimulating Factor Receptors 100%
  • Thrombopoietin Receptors 97%
  • flt3 ligand protein 95%
  • Colony Stimulating Factor 95%
  • Stem Cell Factor 77%
  32 被引用数 (Scopus)

• The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells

  Matsumura, I., Kanakura, Y., Kato, T., Ikeda, H., Horikawa, Y., Ishikawa, J., Kitayama, H., Nishiura, T., Tomiyama, Y., Miyazaki, H. & Matsuzawa, Y., 1996 10月 15, In: Blood. 88, 8, p. 3074-3082 9 p.

  研究成果: Article › 査読

  Open Access

  • Thrombopoietin 100%
  • Acute Myeloid Leukemia 70%
  • Tyrosine 67%
  • Suspension 57%
  • Thrombopoietin Receptors 10%
  35 被引用数 (Scopus)

• Thrombopoietin has a direct effect on erythroid differentiation

  Yamada, M., Komatsu, N., Kirito, K., Shimizu, R., Kato, T., Mivazak, R., Abe, P. K. & Miura, Y., 1996 12月 1, In: Experimental Hematology. 24, 9, 1 p.

  研究成果: Article › 査読

  • Thrombopoietin 100%
  • Erythropoietin Receptors 29%
  • Erythropoietin 22%
  • Dianisidine 18%
  • Thrombopoietin Receptors 16%

• Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists

  Oda, A., Miyakawa, Y., Druker, B. J., Ozaki, K., Yabusaki, K., Shirasawa, Y., Handa, M., Kato, T., Miyazaki, H., Shimosaka, A. & Ikeda, Y., 1996 6月 1, In: Blood. 87, 11, p. 4664-4670 7 p.

  研究成果: Article › 査読

  Open Access

  • Thrombopoietin 100%
  • Shear Stress 88%
  • Platelet Aggregation 74%
  • Agonist 70%
  • Plasma 45%
  117 被引用数 (Scopus)

• Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with steel factor and/or interleukin-3

  Kobayashi, M., Laver, J. H., Kato, T., Miyazaki, H. & Ogawa, M., 1996 7月 15, In: Blood. 88, 2, p. 429-436 8 p.

  研究成果: Article › 査読

  Open Access

  • Thrombopoietin 100%
  • Stem Cell Factor 89%
  • Interleukin-3 87%
  • Suspension 57%
  • Colony Stimulating Factor 36%
  191 被引用数 (Scopus)
• 1997

  Action of thrombopoietin at the megakaryocyte progenitor level is critical for the subsequent proplatelet production

  Horie, K., Miyazaki, H., Hagiwara, T., Tahara, E., Matsumoto, A., Kadoya, T., Ogami, K. & Kato, T., 1997 3月 13, In: Experimental Hematology. 25, 2, p. 169-176 8 p.

  研究成果: Article › 査読

  • Megakaryocyte Progenitor Cells 100%
  • Thrombopoietin 87%
  • Megakaryocytes 78%
  • Thrombopoiesis 9%
  • Interleukin-11 9%
  37 被引用数 (Scopus)