Takashi Kato

2004

Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

Feese, M. D., Tamada, T., Kato, Y., Maeda, Y., Hirose, M., Matsukura, Y., Shigematsu, H., Muto, T., Matsumoto, A., Watarai, H., Ogami, K., Tahara, T., Kato, T., Miyazaki, H. & Kuroki, R., 2004 2月 17, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 7, p. 1816-1821 6 p.

研究成果: Article › 査読

73 被引用数 (Scopus)

2003

CrkL directs ASAP1 to peripheral focal adhesions

Oda, A., Wada, I., Miura, K., Okawa, K., Kadoya, T., Kato, T., Nishihara, H., Maeda, M., Tanaka, S., Nagashima, K., Nishitani, C., Matsuno, K., Ishino, M., Machesky, L. M., Fujita, H. & Randazzo, P., 2003 2月 21, In: Journal of Biological Chemistry. 278, 8, p. 6456-6460 5 p.

研究成果: Article › 査読

38 被引用数 (Scopus)

2002

Crystallization of the functional domain of human thrombopoietin using an antigen-binding fragment derived from neutralizing monoclonal antibody

Kuroki, R., Hirose, M., Kato, Y., Feese, M. D., Tamada, T., Shigematsu, H., Watarai, H., Maeda, Y., Tahara, T., Kato, T. & Miyazaki, H., 2002 1月 1, In: Acta Crystallographica Section D: Biological Crystallography. 58, 5, p. 856-858 3 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Elevation of serum thrombopoietin precedes thrombocytosis in acute infections

Shimbo, T., Mito, M., Suzuki, Y., Ishiguro, A., Matsubara, K., Miyazaki, H. & Kato, T., 2002, In: British Journal of Haematology. 116, 3, p. 612-618 7 p.

研究成果: Article › 査読

61 被引用数 (Scopus)

Marked improvement of thrombocytopenia in a murine model of idiopathic thrombocytopenic purpura by pegylated recombinant human megakaryocyte growth and development factor

Shibuya, K., Kuwaki, T., Tahara, E., Yuki, C., Akahori, H., Kato, T. & Miyazaki, H., 2002 10月 1, In: Experimental Hematology. 30, 10, p. 1185-1192 8 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

New human myelodysplastic cell line, TER-3: G-CSF specific downregulation of Ca ²⁺/calmodulin-dependent protein kinase IV

Mishima, Y., Terui, Y., Mishima, Y., Katsuyama, M., Mori, M., Tomizuka, H., Takizawa, T., Miyazato, A., Ueda, M., Yamada, M., Hayasawa, H., Mizunuma, N., Ishizaka, Y., Ikeda, K., Kato, T., Ozawa, K. & Hatake, K., 2002, In: Journal of Cellular Physiology. 191, 2, p. 183-190 8 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Role of the thrombopoietin (TPO)/Mpl system: c-Mpl-like molecule/TPO signaling enhances early hematopoiesis in Xenopus laevis

Kakeda, M., Kyuno, J. I., Kato, T., Nishikawa, M. & Asashima, M., 2002, In: Development Growth and Differentiation. 44, 1, p. 63-75 13 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Thrombopoietin receptor (c-Mpl) is constitutively expressed on platelets of patients with liver cirrhosis, and correlates with its disease progression

Ishikawa, T., Ichida, T., Sugahara, S., Yamagiwa, S., Matsuda, Y., Uehara, K., Kato, T., Miyazaki, H. & Asakura, H., 2002 6月 1, In: Hepatology Research. 23, 2, p. 115-121 7 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

2001

An increase in circulating mast cell colony-forming cells in asthma

Mwamtemi, H. H., Koike, K., Kinoshita, T., Ito, S., Ishida, S., Nakazawa, Y., Kurokawa, Y., Shinozaki, K., Sakashita, K., Takeuchi, K., Shiohara, M., Kamijo, T., Yasui, Y., Ishiguro, A., Kawano, Y., Kitano, K., Miyazaki, H., Kato, T., Sakuma, S. & Komiyama, A., 2001 4月 1, In: Journal of Immunology. 166, 7, p. 4672-4677 6 p.

研究成果: Article › 査読

Open Access

40 被引用数 (Scopus)

Early elevation of serum thrombopoietin levels and subsequent thrombocytosis in healthy preterm infants

Matsubara, K., Baba, K., Nigami, H., Harigaya, H., Ishiguro, A., Kato, T. & Miyazaki, H., 2001, In: British Journal of Haematology. 115, 4, p. 963-968 6 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Involvement of protein kinase C-ε in signal transduction of thrombopoietin in enhancement of interleukin-3-dependent proliferation of primitive hematopoietic progenitors

Shiroshita, N., Musashi, M., Sakurada, K., Kimura, K., Tsuda, Y., Ota, S., Iwasaki, H., Miyazaki, T., Kato, T., Miyazaki, H., Shimosaka, A. & Asaka, M., 2001 6月, In: Journal of Pharmacology and Experimental Therapeutics. 297, 3, p. 868-875 8 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Platelets exposed to elevated levels of endogenous thrombopoietin in vivo have a reduced response to megakaryocyte growth and development factor in vitro

Nishiyama, U., Morita, H., Torii, Y., Kuwaki, T., Shimizu, E., Akahori, H., Kato, T. & Miyazaki, H., 2001 1月 1, In: Thrombosis and Haemostasis. 85, 1, p. 152-159 8 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

2000

Effect of thrombopoietin on proliferation of blasts from patients with myelodysplastic syndromes

Luo, S. S., Ogata, K., Yokose, N., Kato, T. & Kazuo, D., 2000, In: STEM CELLS. 18, 2, p. 112-119 8 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Expression of hepatic thrombopoietin mRNA in primary cultured hepatocytes and in rats with acute liver injury or bone marrow suppression with or without cirrhosis

Ishikawa, T., Ichida, T., Matsuda, Y., Sugitani, S., Sugiyama, M., Kato, T., Miyazaki, H. & Asakura, H., 2000 1月 1, In: Journal of Gastroenterology and Hepatology (Australia). 15, 6, p. 647-653 7 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Functional analysis of the c-terminal region of recombinant human thrombopoietin. C-terminal region of thrombopoietin is a 'shuttle' peptide to help secretion

Muto, T., Feese, M. D., Shimada, Y., Kudou, Y., Okamoto, T., Ozawa, T., Tahara, T., Ohashi, H., Ogami, K., Kato, T., Miyazaki, H. & Kuroki, R., 2000 4月 21, In: Journal of Biological Chemistry. 275, 16, p. 12090-12094 5 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line

Matsumura, I., Tanaka, H., Kawasaki, A., Odajima, J., Daino, H., Hashimoto, K., Wakao, H., Nakajima, K., Kato, T., Miyazaki, H. & Kanakura, Y., 2000 2月 25, In: Journal of Biological Chemistry. 275, 8, p. 5553-5559 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Stressful delivery influences circulating thrombopoietin (TPO) levels in newborns: Possible role for cortisol in TPO-mpl binding

Ikeno, K., Koike, K., Takeshita, A., Shinjo, K., Higuchi, T., Nakabayashi, T., Akanuma, S., Hizume, K., Ishiguro, A., Ogami, K., Kato, T., Miyazaki, H., Ohno, R. & Komiyama, A., 2000 6月, In: Early Human Development. 58, 3, p. 225-235 11 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Strong inverse correlation between serum TPO level and platelet count in essential thrombocythemia

Tomita, N., Motomura, S., Sakai, R., Fujimaki, K., Tanabe, J., Fukawa, H., Harano, H., Kanamori, H., Ogawa, K., Mohri, H., Maruta, A., Kodama, F., Ishigatsubo, Y., Tahara, T. & Kato, T., 2000, In: American Journal of Hematology. 63, 3, p. 131-135 5 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Thrombopoietin enhances neutrophil production by bone marrow hematopoietic progenitors with the aid of stem cell factor in congenital neutropenia

Sawai, N., Koike, K., Mwamtemi, H. H., Ito, S., Kurokawa, Y., Sakashita, K., Kinoshita, T., Higuchi, T., Takeuchi, K., Shiohara, M., Kamijo, T., Higuchi, Y., Miyazaki, H., Kato, T., Kobayashi, M., Miyake, M., Yasui, K. & Komiyama, A., 2000, In: Journal of Leukocyte Biology. 68, 1, p. 137-143 7 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

1999

Age-related changes in thrombopoietin in children: Reference interval for serum thrombopoietin levels

Ishiguro, A., Nakahata, T., Matsubara, K., Hayashi, Y., Kato, T., Suzuki, Y. & Shimbo, T., 1999, In: British Journal of Haematology. 106, 4, p. 884-888 5 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

Characterization of native human thrombopoietin in the blood of normal individuals and of patients with haematologic disorders

Matsumoto, A., Tahara, T., Morita, H., Usuki, K., Ohashi, H., Kokubo-Watarai, A., Takahashi, K., Shimizu, E., Tsunakawa, H., Ogami, K., Miyazaki, H., Urabe, A. & Kato, T., 1999, In: Thrombosis and Haemostasis. 82, 1, p. 24-29 6 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Liver cirrhosis with marked thrombocytopenia and highly elevated serum thrombopoietin levels

Kitano, K., Shimodaira, S., Ito, T., Ichikawa, N., Kodaira, H., Kohara, Y., Ueno, M., Tahara, T., Kato, T., Ishida, F. & Kiyosawa, K., 1999, In: International Journal of Hematology. 70, 1, p. 52-55 4 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Neutrophilic cell production by combination of stem cell factor and thrombopoietin from CD34⁺ cord blood cells in long-term serum-deprived liquid culture

Sawai, N., Koike, K., Ito, S., Mwamtemi, H. H., Kurokawa, Y., Kinoshita, T., Sakashita, K., Higuchi, T., Takeuchi, K., Shiohara, M., Miyazaki, H., Kato, T. & Komiyama, A., 1999 1月 15, In: Blood. 93, 2, p. 509-518 10 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Production of thrombopoietin by human carcinomas and its novel isoforms

Sasaki, Y., Takahashi, T., Miyazaki, H., Matsumoto, A., Kato, T., Nakamura, K., Iho, S., Okuno, Y. & Nakao, K., 1999 9月 15, In: Blood. 94, 6, p. 1952-1960 9 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

Serial serum thrombopoietin levels in a pregnant woman with essential thrombocythaemia

Kanda, Y., Cliiba, S., Tanaka, Y., Mlu'A, A., Togawa, A., Kato, T., Miyazaki, H., Nisnino, R., Yazaki, Y. & Hirai, H., 1999, In: British Journal of Haematology. 105, 1, p. 271-273 3 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Serum thrombopoietin and erythropoietin levels in patients with acute promyelocytic leukaemia during all-trans retinoic acid treatment

Kinjo, K., Kizaki, M., Takayama, N., Michikawa, N., Oda, A., Okamoto, S. I., Tahara, T., Kato, T., Miyazaki, H. & Ikeda, Y., 1999, In: British Journal of Haematology. 105, 2, p. 382-387 6 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Successful bone marrow transplantation in a child with X-linked hyper-IgM syndrome

Kato, T., Tsuge, I., Inaba, J., Kato, K., Matsuyama, T. & Kojima, S., 1999, In: Bone Marrow Transplantation. 23, 10, p. 1081-1083 3 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

The relationship between carboplatin AUC and serum thrombopoietin kinetics in patients with lung cancer

Miyazaki, M., Fujiwara, Y., Isobe, T., Yamakido, M., Kato, T. & Miyazaki, H., 1999 4月 20, In: Anticancer Research. 19, 1 B, p. 667-670 4 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Thrombopoietin augments stem cell factor-dependent growth of human mast cells from bone marrow multipotential hematopoietic progenitors

Sawai, N., Koike, K., Mwamtemi, H. H., Kinoshita, T., Kurokawa, Y., Sakashita, K., Higuchi, T., Takeuchi, K., Shiohara, M., Kamijo, T., Ito, S., Kato, T., Miyazaki, H., Yamashita, T. & Komiyama, A., 1999 6月 1, In: Blood. 93, 11, p. 3703-3712 10 p.

研究成果: Article › 査読

43 被引用数 (Scopus)

Thrombopoietin expression in normal and hypobaric hypoxia-induced thrombocytopenic rats

Nakanishi, K., Tajima, F., Osada, H., Kato, T., Miyazaki, H., Kawai, T., Torikata, C., Suga, T., Takishima, K., Aurues, T. & Ikeda, T., 1999 6月 1, In: Laboratory Investigation. 79, 6, p. 679-688 10 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Thrombopoietin-induced signal transduction and potentiation of platelet activation

Oda, A., Miyakawa, Y., Druker, B. J., Ozaki, K., Ohashi, H., Kato, T., Miyazaki, H., Handa, M., Ikebuchi, K. & Ikeda, Y., 1999, In: Thrombosis and Haemostasis. 82, 2, p. 377-384 8 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

1998

Changes in serum thrombopoietin levels after splenectomy

Ichikawa, N., Kitano, K., Shimodaira, S., Ishida, F., Ito, T., Kajikawa, S., Tahara, T., Kato, T. & Kiyosawa, K., 1998, In: Acta Haematologica. 100, 3, p. 137-141 5 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Evaluation of thrombopoiesis in thrombocytopenic disorders by simultaneous measurement of reticulated platelets of whole blood and serum thrombopoietin concentrations

Koike, Y., Yoneyama, A., Shirai, J., Ishida, T., Shoda, E., Miyazaki, K., Sunaga, S., Horie, R., Aoki, K., Koike, K., Ogata, I., Tahara, T., Kato, T., Nakahara, K., Kariya, T. & Higashihara, M., 1998, In: Thrombosis and Haemostasis. 79, 6, p. 1106-1110 5 p.

研究成果: Article › 査読

87 被引用数 (Scopus)

Further examination of various administration protocols of pegylated recombinant human megakaryocyte growth and development factor on thrombocytopenia in myelosuppressed mice

Akahori, H., Ozai, M., Ida, M., Shibuya, K., Kato, T. & Miyazaki, H., 1998 2月, In: Therapeutic Apheresis. 2, 1, p. 58-64 7 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Increased thrombopoietin levels in idiopathic thrombocytopenic purpura patients with a poor response to steroid therapy

Sakane, Y., Wada, H., Kazuyo, H., Shimura, M., Nakasaki, T., Katayama, N., Nishikawa, M., Deguchi, K., Mori, Y., Shiku, H., Tahara, T. & Kato, T., 1998 1月 1, In: Blood Coagulation and Fibrinolysis. 9, 4, p. 315-321 7 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line

Matsumura, I., Nakajima, K., Wakao, H., Hattori, S., Hashimoto, K., Sugahara, H., Kato, T., Miyazaki, H., Hirano, T. & Kanakura, Y., 1998 7月, In: Molecular and Cellular Biology. 18, 7, p. 4282-4290 9 p.

研究成果: Article › 査読

70 被引用数 (Scopus)

Mobilization of primitive haemopoietic progenitor cells and stem cells with long-term repopulating ability into peripheral blood in mice by pegylated recombinant human megakaryocyte growth and development factor

Torii, Y., Nitta, Y., Akahori, H., Tawara, T., Kuwaki, T., Ogami, K., Kato, T. & Miyazaki, H., 1998, In: British Journal of Haematology. 103, 4, p. 1172-1180 9 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Molecular cloning and functional expression of feline thrombopoietin

Matsushiro, H., Kato, H., Tahara, T., Kato, T., Iwata, A., Watari, T., Tsujimoto, H. & Hasegawa, A., 1998 12月 11, In: Veterinary Immunology and Immunopathology. 66, 3-4, p. 225-236 12 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice

Shibuya, K., Akahori, H., Takahashi, K., Tahara, E., Kato, T. & Miyazaki, H., 1998 1月 1, In: Blood. 91, 1, p. 37-45 9 p.

研究成果: Article › 査読

Open Access

59 被引用数 (Scopus)

Native thrombopoietin: Structure and function

Kato, T., Matsumoto, A., Ogami, K., Tahara, T., Morita, H. & Miyazaki, H., 1998, In: STEM CELLS. 16, 5, p. 322-328 7 p.

研究成果: Article › 査読

Open Access

42 被引用数 (Scopus)

Neutralization of biological activity and inhibition of receptor binding by antibodies against human thrombopoietin

Tahara, T., Kuwaki, T., Matsumoto, A., Morita, H., Watarai, H., Inagaki, Y., Ohashi, H., Ogami, K., Miyazaki, H. & Kato, T., 1998, In: STEM CELLS. 16, 1, p. 54-60 7 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Plasma thrombopoietin (TPO) levels and expression of TPO receptor on platelets in patients with myelodysplastic syndromes

Tamura, H., Ogata, K., Luo, S., Nakamura, K., Yokose, N., Dan, K., Tohyama, K., Yoshida, Y., Hamaguchi, H., Sakamaki, H., Kuwaki, T., Tahara, T., Kato, T. & Nomura, T., 1998, In: British Journal of Haematology. 103, 3, p. 778-784 7 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Proliferative properties of human umbilical cord blood megakaryocyte progenitor cells to human thrombopoietin

Hagiwara, T., Kodama, I., Horie, K., Kato, T. & Miyazaki, H., 1998 3月 21, In: Experimental Hematology. 26, 3, p. 228-235 8 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

Quantitative analysis of thrombopoietin receptors on human megakaryocytes

Kuwaki, T., Hagiwara, T., Yuki, C., Kodama, I., Kato, T. & Miyazaki, H., 1998 5月 1, In: FEBS Letters. 427, 1, p. 46-50 5 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Reduced expression of thrombopoietin is involved in thrombocytopenia in human and rat liver cirrhosis

Ishikawa, T., Ichida, T., Matsuda, Y., Sugitani, S., Sugiyama, M., Kato, T., Miyazaki, H. & Asakura, H., 1998, In: Journal of Gastroenterology and Hepatology (Australia). 13, 9, p. 907-913 7 p.

研究成果: Article › 査読

61 被引用数 (Scopus)

Thrombopoietin in patients with hepatoblastorna

Komura, E., Matsumura, T., Kato, T., Tahara, T., Tsunoda, Y. & Sawada, T., 1998, In: STEM CELLS. 16, 5, p. 329-333 5 p.

研究成果: Article › 査読

43 被引用数 (Scopus)

Thrombopoietin level is inversely related to blast count, not platelet number, in Down syndrome neonates with transient myeloproliferative disorder

Bonno, M., Azuma, E., Kawasaki, H., Zhang, X. L., Komada, Y., Hirayama, M., Higashigawa, M., Umemoto, M., Koike, T., Kato, T., Tahara, T., Miyazaki, H. & Sakurai, M., 1998 8月, In: American Journal of Hematology. 58, 4, p. 267-272 6 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Thrombopoietin promotes the survival of murine hematopoietic long-term reconstituting cells: Comparison with the effects of FLT3/FLK-2 ligand and interleukin-6

Matsunaga, T., Kato, T., Miyazaki, H. & Ogawa, M., 1998 7月 15, In: Blood. 92, 2, p. 452-461 10 p.

研究成果: Article › 査読

71 被引用数 (Scopus)

Thrombopoietin stimulates proliferation and megakaryocytic differentiation of mouse pro-B cell line BF-TE22

Ohashi, H., Morita, H., Tahara, T., Tsunakawa, H., Matsumoto, A., Ogami, K., Kato, T. & Miyazaki, H., 1998, In: Cytotechnology. 26, 3, p. 199-206 8 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

1997

Action of thrombopoietin at the megakaryocyte progenitor level is critical for the subsequent proplatelet production

Horie, K., Miyazaki, H., Hagiwara, T., Tahara, E., Matsumoto, A., Kadoya, T., Ogami, K. & Kato, T., 1997 3月 13, In: Experimental Hematology. 25, 2, p. 169-176 8 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

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