Takashi Kato

Fluorescence labeling of a cytokine with desthiobiotin-tagged fluorescent puromycin

Sakamoto, A., Yamagishi, M., Watanabe, T., Aizawa, Y., Kato, T. & Funatsu, T., 2008 3月, In: Journal of Bioscience and Bioengineering. 105, 3, p. 238-242 5 p.

研究成果: Article › 査読

Functional analysis of the c-terminal region of recombinant human thrombopoietin. C-terminal region of thrombopoietin is a 'shuttle' peptide to help secretion

Muto, T., Feese, M. D., Shimada, Y., Kudou, Y., Okamoto, T., Ozawa, T., Tahara, T., Ohashi, H., Ogami, K., Kato, T., Miyazaki, H. & Kuroki, R., 2000 4月 21, In: Journal of Biological Chemistry. 275, 16, p. 12090-12094 5 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation

Morita, H., Tahara, T., Matsumoto, A., Kato, T., Miyazaki, H. & Ohashi, H., 1996 10月 21, In: FEBS Letters. 395, 2-3, p. 228-234 7 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

Further examination of various administration protocols of pegylated recombinant human megakaryocyte growth and development factor on thrombocytopenia in myelosuppressed mice

Akahori, H., Ozai, M., Ida, M., Shibuya, K., Kato, T. & Miyazaki, H., 1998 2月, In: Therapeutic Apheresis. 2, 1, p. 58-64 7 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

GpIIb/IIIa⁺ subpopulation of rat megakaryocyte progenitor cells exhibits high responsiveness to human thrombopoietin

Kato, T., Horie, K., Hagiwara, T., Maeda, E., Tsumura, H., Ohashi, H. & Miyazaki, H., 1996 9月 3, In: Experimental Hematology. 24, 10, p. 1209-1214 6 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Growth factor‐induced process formation of megakaryocytes derived from CFU‐MK

Inoue, H., Ishii, H., Tsutsumi, M., Takahashi, N., Sato, M., Shimada, Y., Kato, T., Sudo, T. & Miyazaki, H., 1993 10月, In: British Journal of Haematology. 85, 2, p. 260-269 10 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin

Matsumura, I., Kanakura, Y., Kato, T., Ikeda, H., Ishikawa, J., Horikawa, Y., Hashimoto, K., Moriyama, Y., Tsujimura, T., Nishiura, T., Miyazaki, H. & Matsuzawa, Y., 1995 7月 15, In: Blood. 86, 2, p. 703-709 7 p.

研究成果: Article › 査読

Open Access

88 被引用数 (Scopus)

Hepatic confinement of newly produced erythrocytes caused by low-temperature exposure in Xenopus laevis

Maekawa, S., Iemura, H., Kuramochi, Y., Nogawa-Kosaka, N., Nishikawa, H., Okui, T., Aizawa, Y. & Kato, T., 2012 9月, In: Journal of Experimental Biology. 215, 17, p. 3087-3095 9 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by FcεRI cross-linking

Fukamachi, H., Yamada, N., Miura, T., Kato, T., Ishikawa, M., Gulbins, E., Altman, A., Kawakami, Y. & Kawakami, T., 1994 1月 15, In: Journal of Immunology. 152, 2, p. 642-652 11 p.

研究成果: Article › 査読

46 被引用数 (Scopus)

Identification of erythroid progenitors induced by erythropoietic activity in Xenopus laevis

Nogawa-Kosaka, N., Sugai, T., Nagasawa, K., Tanizaki, Y., Meguro, M., Aizawa, Y., Maekawa, S., Adachi, M., Kuroki, R. & Kato, T., 2011 3月, In: Journal of Experimental Biology. 214, 6, p. 921-927 7 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Identification of erythropoietin-induced microRNAs in haematopoietic cells during erythroid differentiation

Kosaka, N., Sugiura, K., Yamamoto, Y., Yoshioka, Y., Miyazaki, H., Komatsu, N., Ochiya, T. & Kato, T., 2008 7月, In: British Journal of Haematology. 142, 2, p. 293-300 8 p.

研究成果: Article › 査読

40 被引用数 (Scopus)

IFATS collection: In vivo therapeutic potential of human adipose tissue mesenchymal stem cells after transplantation into mice with liver injury

Banas, A., Teratani, T., Yamamoto, Y., Tokuhara, M., Takeshita, F., Osaki, M., Kawamata, M., Kato, T., Okochi, H. & Ochiya, T., 2008 10月, In: STEM CELLS. 26, 10, p. 2705-2712 8 p.

研究成果: Article › 査読

252 被引用数 (Scopus)

Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets

Tanaka, S., Kurabuchi, S., Mochida, H., Kato, T., Takahashi, S., Watanabe, T. & Nakayama, K., 1996, In: Archives of Histology and Cytology. 59, 3, p. 261-271 11 p.

研究成果: Article › 査読

Open Access

48 被引用数 (Scopus)

Improvement of thrombocytopenia following bone marrow transplantation by pegylated recombinant human megakaryocyte growth and development factor in mice

Kabaya, K., Shibuya, K., Torii, Y., Nitta, Y., Ida, M., Akahori, H., Kato, T., Kusaka, M. & Miyazaki, H., 1996 12月 1, In: Bone Marrow Transplantation. 18, 6, p. 1035-1041 7 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line

Matsumura, I., Tanaka, H., Kawasaki, A., Odajima, J., Daino, H., Hashimoto, K., Wakao, H., Nakajima, K., Kato, T., Miyazaki, H. & Kanakura, Y., 2000 2月 25, In: Journal of Biological Chemistry. 275, 8, p. 5553-5559 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Increased serum levels of thrombopoietin in patients with thrombotic thrombocytopenic purpura, idiopathic thrombocytopenic purpura, or disseminated intravascular coagulation

Hiyoyama, K., Wada, H., Shimura, M., Nakasaki, T., Katayama, N., Nishikawa, M., Shiku, H., Tahara, T. & Kato, T., 1997 1月 1, In: Blood Coagulation and Fibrinolysis. 8, 6, p. 345-349 5 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Increased thrombopoietin levels in idiopathic thrombocytopenic purpura patients with a poor response to steroid therapy

Sakane, Y., Wada, H., Kazuyo, H., Shimura, M., Nakasaki, T., Katayama, N., Nishikawa, M., Deguchi, K., Mori, Y., Shiku, H., Tahara, T. & Kato, T., 1998 1月 1, In: Blood Coagulation and Fibrinolysis. 9, 4, p. 315-321 7 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

In vivo effects of pegylated recombinant human megakaryocyte growth and development factor on hematopoiesis in normal mice

Kabaya, K., Akahori, H., Shibuya, K., Nitta, Y., Ida, M., Kusaka, M., Kato, T. & Miyazaki, H., 1996 11月, In: STEM CELLS. 14, 6, p. 651-660 10 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line

Matsumura, I., Nakajima, K., Wakao, H., Hattori, S., Hashimoto, K., Sugahara, H., Kato, T., Miyazaki, H., Hirano, T. & Kanakura, Y., 1998 7月, In: Molecular and Cellular Biology. 18, 7, p. 4282-4290 9 p.

研究成果: Article › 査読

70 被引用数 (Scopus)

Involvement of protein kinase C-ε in signal transduction of thrombopoietin in enhancement of interleukin-3-dependent proliferation of primitive hematopoietic progenitors

Shiroshita, N., Musashi, M., Sakurada, K., Kimura, K., Tsuda, Y., Ota, S., Iwasaki, H., Miyazaki, T., Kato, T., Miyazaki, H., Shimosaka, A. & Asaka, M., 2001 6月, In: Journal of Pharmacology and Experimental Therapeutics. 297, 3, p. 868-875 8 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Isolation, characterization and bioactivity of a region-specific pheromone, [Val⁸]sodefrin from the newt Cynops pyrrhogaster

Nakada, T., Toyoda, F., Iwata, T., Yamamoto, K., Conlon, J. M., Kato, T. & Kikuyama, S., 2007 4月, In: Peptides. 28, 4, p. 774-780 7 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Liver cirrhosis with marked thrombocytopenia and highly elevated serum thrombopoietin levels

Kitano, K., Shimodaira, S., Ito, T., Ichikawa, N., Kodaira, H., Kohara, Y., Ueno, M., Tahara, T., Kato, T., Ishida, F. & Kiyosawa, K., 1999, In: International Journal of Hematology. 70, 1, p. 52-55 4 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Marked improvement of thrombocytopenia in a murine model of idiopathic thrombocytopenic purpura by pegylated recombinant human megakaryocyte growth and development factor

Shibuya, K., Kuwaki, T., Tahara, E., Yuki, C., Akahori, H., Kato, T. & Miyazaki, H., 2002 10月 1, In: Experimental Hematology. 30, 10, p. 1185-1192 8 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Markedly reduced expression of platelet c-mpl receptor in essential thrombocythemia

Horikawa, Y., Matsumura, I., Hashimoto, K., Shiraga, M., Kosugi, S., Tadokoro, S., Kato, T., Miyazaki, H., Tomiyama, Y., Kurata, Y., Matsuzawa, Y. & Kanakura, Y., 1997 11月 15, In: Blood. 90, 10, p. 4031-4038 8 p.

研究成果: Article › 査読

Open Access

168 被引用数 (Scopus)

Measurement of endogenous plasma thrombopoietin in patients with acquired aplastic anaemia by a sensitive enzyme-linked immunosorbent assay

Kojima, S., Matsuyama, T., Kodera, Y., Tahara, T. & Kato, T., 1997, In: British Journal of Haematology. 97, 3, p. 538-543 6 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

MEG3-derived miR-493-5p overcomes the oncogenic feature of IGF2-miR-483 loss of imprinting in hepatic cancer cells

Gailhouste, L., Liew, L. C., Yasukawa, K., Hatada, I., Tanaka, Y., Kato, T., Nakagama, H. & Ochiya, T., 2019 8月 1, In: Cell Death and Disease. 10, 8, 553.

研究成果: Article › 査読

Open Access

25 被引用数 (Scopus)

Megakaryocyte growth and development factor: Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy- induced thrombocytopenia

Nichol, J. L., Hokom, M. M., Hornkohl, A., Sheridan, W. P., Ohashi, H., Kato, T., Yue Sheng Li, S. L., Bartley, T. D., Choi, E., Bogenberger, J., Skrine, J. D., Knudten, A., Chen, J., Trail, G., Sleeman, L., Cole, S., Grampp, G. & Hunt, P., 1995, In: Journal of Clinical Investigation. 95, 6, p. 2973-2978 6 p.

研究成果: Article › 査読

Open Access

193 被引用数 (Scopus)

Megakaryocytes derived from CD34-positive cord blood cells produce interleukin-8

Higuchi, T., Koike, K., Sawai, N., Mwamtemi, H. H., Takeuchi, K., Shiohara, M., Kikuchi, T., Yasui, K., Ito, S., Yamagami, O., Sasaki, Y., Okumura, N., Kato, T., Miyazaki, H., Ikeda, M., Yamada, M. & Komiyama, A., 1997, In: British Journal of Haematology. 99, 3, p. 509-516 8 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Micromanaging iron homeostasis: Hypoxia-inducible micro-RNA-210 suppresses iron homeostasis-related proteins

Yoshioka, Y., Kosaka, N., Ochiya, T. & Kato, T., 2012 10月 5, In: Journal of Biological Chemistry. 287, 41, p. 34110-34119 10 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

MicroRNA-493-5p-mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion

Yasukawa, K., Liew, L. C., Hagiwara, K., Hironaka-Mitsuhashi, A., Qin, X. Y., Furutani, Y., Tanaka, Y., Nakagama, H., Kojima, S., Kato, T., Ochiya, T. & Gailhouste, L., 2020 3月 1, In: Cancer Science. 111, 3, p. 869-880 12 p.

研究成果: Article › 査読

Open Access

16 被引用数 (Scopus)

MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma

Yamamoto, Y., Kosaka, N., Tanaka, M., Koizumi, F., Kanai, Y., Mizutani, T., Murakami, Y., Kuroda, M., Miyajima, A., Kato, T. & Ochiya, T., 2009, In: Biomarkers. 14, 7, p. 529-538 10 p.

研究成果: Article › 査読

185 被引用数 (Scopus)

Mobilization of primitive haemopoietic progenitor cells and stem cells with long-term repopulating ability into peripheral blood in mice by pegylated recombinant human megakaryocyte growth and development factor

Torii, Y., Nitta, Y., Akahori, H., Tawara, T., Kuwaki, T., Ogami, K., Kato, T. & Miyazaki, H., 1998, In: British Journal of Haematology. 103, 4, p. 1172-1180 9 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Molecular cloning and chromosomal localization of the human thrombopoietin gene

Sohma, Y., Akahori, H., Seki, N., Hori, T. A., Ogami, K., Kato, T., Shimada, Y., Kawamura, K. & Miyazaki, H., 1994 10月 10, In: FEBS Letters. 353, 1, p. 57-61 5 p.

研究成果: Article › 査読

239 被引用数 (Scopus)

Molecular cloning and chromosomal localization of the human thrombopoietin gene Yoshiaki Sohma a, Hiromichi Akahori a, Naohiko Seki b,c, Tada-aki Hori b, Kinya Ogami a

Kato, T., 1994, In: FEBS Letters. 353, 1, p. 57-61 5 p.

研究成果: Article › 査読

Molecular cloning and functional expression of feline thrombopoietin

Matsushiro, H., Kato, H., Tahara, T., Kato, T., Iwata, A., Watari, T., Tsujimoto, H. & Hasegawa, A., 1998 12月 11, In: Veterinary Immunology and Immunopathology. 66, 3-4, p. 225-236 12 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice

Shibuya, K., Akahori, H., Takahashi, K., Tahara, E., Kato, T. & Miyazaki, H., 1998 1月 1, In: Blood. 91, 1, p. 37-45 9 p.

研究成果: Article › 査読

Open Access

59 被引用数 (Scopus)

Multiple origins of embryonic and tadpole myeloid cells in Xenopus laevis

Imai, Y., Ishida, K., Nemoto, M., Nakata, K., Kato, T. & Maéno, M., 2017 8月 1, In: Cell and Tissue Research. 369, 2, p. 341-352 12 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Native thrombopoietin: Structure and function

Kato, T., Matsumoto, A., Ogami, K., Tahara, T., Morita, H. & Miyazaki, H., 1998, In: STEM CELLS. 16, 5, p. 322-328 7 p.

研究成果: Article › 査読

42 被引用数 (Scopus)

Neutralization of biological activity and inhibition of receptor binding by antibodies against human thrombopoietin

Tahara, T., Kuwaki, T., Matsumoto, A., Morita, H., Watarai, H., Inagaki, Y., Ohashi, H., Ogami, K., Miyazaki, H. & Kato, T., 1998, In: STEM CELLS. 16, 1, p. 54-60 7 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Neutrophilic cell production by combination of stem cell factor and thrombopoietin from CD34⁺ cord blood cells in long-term serum-deprived liquid culture

Sawai, N., Koike, K., Ito, S., Mwamtemi, H. H., Kurokawa, Y., Kinoshita, T., Sakashita, K., Higuchi, T., Takeuchi, K., Shiohara, M., Miyazaki, H., Kato, T. & Komiyama, A., 1999 1月 15, In: Blood. 93, 2, p. 509-518 10 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

New human myelodysplastic cell line, TER-3: G-CSF specific downregulation of Ca ²⁺/calmodulin-dependent protein kinase IV

Mishima, Y., Terui, Y., Mishima, Y., Katsuyama, M., Mori, M., Tomizuka, H., Takizawa, T., Miyazato, A., Ueda, M., Yamada, M., Hayasawa, H., Mizunuma, N., Ishizaka, Y., Ikeda, K., Kato, T., Ozawa, K. & Hatake, K., 2002, In: Journal of Cellular Physiology. 191, 2, p. 183-190 8 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Pegylated recombinant human megakaryocyte growth and development factor suppresses the development of megakaryoblastic leukemia in mice

Shibuya, K., Kuwaki, T., Akahori, H., Kato, T. & Miyazaki, H., 2004 9月 1, In: Leukemia Research. 28, 9, p. 941-946 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Plasma thrombopoietin (TPO) levels and expression of TPO receptor on platelets in patients with myelodysplastic syndromes

Tamura, H., Ogata, K., Luo, S., Nakamura, K., Yokose, N., Dan, K., Tohyama, K., Yoshida, Y., Hamaguchi, H., Sakamaki, H., Kuwaki, T., Tahara, T., Kato, T. & Nomura, T., 1998, In: British Journal of Haematology. 103, 3, p. 778-784 7 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Plasma thrombopoietin concentrations in patients with acquired aplastic anemia

Kojima, S., Matsuyama, T., Kodera, Y., Tahara, T. & Kato, T., 1996, In: Experimental Hematology. 24, 9, p. 1063 1 p.

研究成果: Article › 査読

Platelet-Derived Stromal Cell-Derived Factor-1 Is Required for the Transformation of Circulating Monocytes into Multipotential Cells

Seta, N., Okazaki, Y., Miyazaki, H., Kato, T. & Kuwana, M., 2013 9月 16, In: PloS one. 8, 9, e74246.

研究成果: Article › 査読

15 被引用数 (Scopus)

Platelets exposed to elevated levels of endogenous thrombopoietin in vivo have a reduced response to megakaryocyte growth and development factor in vitro

Nishiyama, U., Morita, H., Torii, Y., Kuwaki, T., Shimizu, E., Akahori, H., Kato, T. & Miyazaki, H., 2001 1月 1, In: Thrombosis and Haemostasis. 85, 1, p. 152-159 8 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Production of erythropoietin‐like activity by human renal and hepatic carcinomas in cell culture

Okabe, T., Urabe, A., Kato, T., Chiba, S. & Takaku, F., 1985 5月 1, In: Cancer. 55, 9, p. 1918-1923 6 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Production of monoclonal antibodies against human erythropoietin and their use in the purification of human urinary erythropoietin

Hiroshi Miyazaki, M., Hiroyuki Kozutsumi, K., Takashi Kato, K., Sakuo Hoshi, H., Setsuko Tamura, T., Mamoru Kubota, K. & Takamoto Suzuki, S., 1988 10月 26, In: Journal of Immunological Methods. 113, 2, p. 261-267 7 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Production of thrombopoietin (TPO) by rat hepatocytes and hepatoma cell lines

Shimada, Y., Kato, T., Ogami, K., Horie, K., Kokubo, A., Kudo, Y., Maeda, E., Sohma, Y., Akahori, H., Kawamura, K. & Miyazaki, H., 1995 12月 1, In: Experimental Hematology. 23, 13, p. 1388-1396 9 p.

研究成果: Article › 査読

86 被引用数 (Scopus)

Production of thrombopoietin by human carcinomas and its novel isoforms

Sasaki, Y., Takahashi, T., Miyazaki, H., Matsumoto, A., Kato, T., Nakamura, K., Iho, S., Okuno, Y. & Nakao, K., 1999 9月 15, In: Blood. 94, 6, p. 1952-1960 9 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

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