Toshiyuki Okano

2020

Adaptive light: a lighting control method aligned with dark adaptation of human vision

Takemura, Y., Ito, M., Shimizu, Y., Okano, K. & Okano, T., 2020 12 1, ： : Scientific reports. 10, 1, 11204.

研究成果: Article

公開

A photoperiodic time measurement served by the biphasic expression of Cryptochrome1ab in the zebrafish eye

Okano, K., Saratani, Y., Tamasawa, A., Shoji, Y., Toda, R. & Okano, T., 2020 12 1, ： : Scientific reports. 10, 1, 5056.

研究成果: Article

公開

Clock Gene Expression in the Eye Exhibits Circadian Oscillation and Light Responsiveness but is Not Necessary for Nocturnal Locomotor Activity of Japanese Loach, Misgurnus anguillicaudatus

Saratani, Y., Takeuchi, Y., Okano, K. & Okano, T., 2020 4 6, ： : Zoological Science. 37, 2, p. 177-192 16 p.

研究成果: Article

2019

THETA system allows one-step isolation of tagged proteins through temperature-dependent protein–peptide interaction

Miura, K., Tsuji, Y., Mitsui, H., Oshima, T., Noshi, Y., Arisawa, Y., Okano, K. & Okano, T., 2019 12 1, ： : Communications Biology. 2, 1, 207.

研究成果: Article

公開

2018

Moonlight controls lunar-phase-dependency and regular oscillation of clock gene expressions in a lunar-synchronized spawner fish, Goldlined spinefoot

Takeuchi, Y., Kabutomori, R., Yamauchi, C., Miyagi, H., Takemura, A., Okano, K. & Okano, T., 2018 12 1, ： : Scientific reports. 8, 1, 6208.

研究成果: Article

7 引用（Scopus）

2017

Light-A nd circadian-controlled genes respond to a broad light spectrum in Puffer Fish-derived Fugu eye cells

Okano, K., Ozawa, S., Sato, H., Kodachi, S., Ito, M., Miyadai, T., Takemura, A. & Okano, T., 2017 4 18, ： : Scientific reports. 7, 46150.

研究成果: Article

4 引用（Scopus）

2015

Overexpression in Yeast, Photocycle, and in Vitro Structural Change of an Avian Putative Magnetoreceptor Cryptochrome4

Mitsui, H., Maeda, T., Yamaguchi, C., Tsuji, Y., Watari, R., Kubo, Y., Okano, K. & Okano, T., 2015 3 17, ： : Biochemistry. 54, 10, p. 1908-1917 10 p.

研究成果: Article

11 引用（Scopus）

Rhodopsin in the dark hot sea: Molecular analysis of rhodopsin in a snailfish, Careproctus rhodomelas, living near the deep-sea hydrothermal vent

Sakata, R., Kabutomori, R., Okano, K., Mitsui, H., Takemura, A., Miwa, T., Yamamoto, H. & Okano, T., 2015 8 14, ： : PloS one. 10, 8, 0135888.

研究成果: Article

3 引用（Scopus）

2014

Hypothalamic expression and moonlight-independent changes of Cry3 and Per4 implicate their roles in lunar clock oscillators of the lunar-responsive goldlined spinefoot

Toda, R., Okano, K., Takeuchi, Y., Yamauchi, C., Fukushiro, M., Takemura, A. & Okano, T., 2014 10 1, ： : PloS one. 9, 10, e109119.

研究成果: Article

9 引用（Scopus）

Identification and characterization of cryptochrome4 in the ovary of western clawed frog xenopus tropicalis

Takeuchi, T., Kubo, Y., Okano, K. & Okano, T., 2014 3 1, ： : Zoological Science. 31, 3, p. 152-159 8 p.

研究成果: Article

7 引用（Scopus）

2012

Light-dependent structural change of chicken retinal cryptochrome4

Watari, R., Yamaguchi, C., Zemba, W., Kubo, Y., Okano, K. & Okano, T., 2012 12 14, ： : Journal of Biological Chemistry. 287, 51, p. 42634-42641 8 p.

研究成果: Article

33 引用（Scopus）

Zebrafish respond to the geomagnetic field by bimodal and group-dependent orientation

Takebe, A., Furutani, T., Wada, T., Koinuma, M., Kubo, Y., Okano, K. & Okano, T., 2012 11 7, ： : Scientific reports. 2, 727.

研究成果: Article

22 引用（Scopus）

2011

Lunar phase-dependent expression of cryptochrome and a photoperiodic mechanism for lunar phase-recognition in a reef fish, goldlined spinefoot

Fukushiro, M., Takeuchi, T., Takeuchi, Y., Hur, S. P., Sugama, N., Takemura, A., Kubo, Y., Okano, K. & Okano, T., 2011 12 7, ： : PloS one. 6, 12, e28643.

研究成果: Article

28 引用（Scopus）

2010

Cryptochrome genes are highly expressed in the ovary of the African clawed frog, Xenopus tropicalis

Kubo, Y., Takeuchi, T., Okano, K. & Okano, T., 2010 2 17, ： : PloS one. 5, 2, e9273.

研究成果: Article

11 引用（Scopus）

Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork

Hirota, T., Kon, N., Itagaki, T., Hoshina, N., Okano, T. & Fukada, Y., 2010 2 1, ： : Genes to Cells. 15, 2, p. 111-121 11 p.

研究成果: Article

23 引用（Scopus）

2009

Macrophage inhibitory cytokine MIC-1 is upregulated by short-wavelength light in cultured normal human dermal fibroblasts

Akiyama, M., Okano, K., Fukada, Y. & Okano, T., 2009 3 4, ： : FEBS Letters. 583, 5, p. 933-937 5 p.

研究成果: Article

13 引用（Scopus）

Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription

Sasaki, M., Yoshitane, H., Du, N. H., Okano, T. & Fukada, Y., 2009 9 11, ： : Journal of Biological Chemistry. 284, 37, p. 25149-25159 11 p.

研究成果: Article

34 引用（Scopus）

Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription

Yoshitane, H., Takao, T., Satomi, Y., Du, N. H., Okano, T. & Fukada, Y., 2009 7 1, ： : Molecular and Cellular Biology. 29, 13, p. 3675-3686 12 p.

研究成果: Article

87 引用（Scopus）

2007

Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in preovulatory ovarian follicles

Nakao, N., Yasuo, S., Nishimura, A., Yamamura, T., Watanabe, T., Anraku, T., Okano, T., Fukada, Y., Sharp, P. J., Ebihara, S. & Yoshimura, T., 2007 7 1, ： : Endocrinology. 148, 7, p. 3031-3038 8 p.

研究成果: Article

86 引用（Scopus）

Two isoforms of chicken melanopsins show blue light sensitivity

Torii, M., Kojima, D., Okano, T., Nakamura, A., Terakita, A., Shichida, Y., Wada, A. & Fukada, Y., 2007 11 13, ： : FEBS Letters. 581, 27, p. 5327-5331 5 p.

研究成果: Article

58 引用（Scopus）

2006

GRK1 and GRK7: Unique cellular distribution and widely different activities of opsin phosphorylation in the zebrafish rods and cones

Wada, Y., Sugiyama, J., Okano, T. & Fukada, Y., 2006 8 1, ： : Journal of neurochemistry. 98, 3, p. 824-837 14 p.

研究成果: Article

37 引用（Scopus）

Lcg is a light-inducible and clock-controlled gene expressed in the chicken pineal gland

Hatori, M., Okano, T., Nakajima, Y., Doi, M. & Fukada, Y., 2006 3 1, ： : Journal of neurochemistry. 96, 6, p. 1790-1800 11 p.

研究成果: Article

5 引用（Scopus）

Molecular cloning, mRNA expression, and immunocytochemical localization of a putative blue-light photoreceptor CRY4 in the chicken pineal gland

Kubo, Y., Akiyama, M., Fukada, Y. & Okano, T., 2006 5 1, ： : Journal of neurochemistry. 97, 4, p. 1155-1165 11 p.

研究成果: Article

19 引用（Scopus）

2005

Farnesylation of retinal transducin underlies its translocation during light adaptation

Kassai, H., Aiba, A., Nakao, K., Nakamura, K., Katsuki, M., Xiong, W. H., Yau, K. W., Imai, H., Shichida, Y., Satomi, Y., Takao, T., Okano, T. & Fukada, Y., 2005 8 18, ： : Neuron. 47, 4, p. 529-539 11 p.

研究成果: Article

36 引用（Scopus）

2004

Negative control of circadian clock regulator E4BP4 by casein kinase Iε-mediated phosphorylation

Doi, M., Okano, T., Yujnovsky, I., Sassone-Corsi, P. & Fukada, Y., 2004 6 8, ： : Current Biology. 14, 11, p. 975-980 6 p.

研究成果: Article

32 引用（Scopus）

2002

A Negative Regulatory Element Required for Light-Dependent pinopsin Gene Expression

Takanaka, Y., Okano, T., Yamamoto, K. & Fukada, Y., 2002 6 1, ： : Journal of Neuroscience. 22, 11, p. 4357-4363 7 p.

研究成果: Article

公開

14 引用（Scopus）

Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured rat-1 fibroblasts

Hirota, T., Okano, T., Kokame, K., Shirotani-Ikejima, H., Miyata, T. & Fukada, Y., 2002 11 15, ： : Journal of Biological Chemistry. 277, 46, p. 44244-44251 8 p.

研究成果: Article

249 引用（Scopus）

Light-dependent changes in the chick pineal temperature and the expression of cHsp90α gene: A potential contribution of in vivo temperature change to the photic-entrainment of the chick pineal circadian clock

Doi, M., Nakajima, Y., Okano, T. & Fukada, Y., 2002 6 1, ： : Zoological Science. 19, 6, p. 633-641 9 p.

研究成果: Article

10 引用（Scopus）

Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1

Sanada, K., Okano, T. & Fukada, Y., 2002 1 4, ： : Journal of Biological Chemistry. 277, 1, p. 267-271 5 p.

研究成果: Article

107 引用（Scopus）

Opsin-G₁₁-mediated signaling pathway for photic entrainment of the chicken pineal circadian clock

Kasahara, T., Okano, T., Haga, T. & Fukada, Y., 2002 9 1, ： : Journal of Neuroscience. 22, 17, p. 7321-7325 5 p.

研究成果: Article

公開

28 引用（Scopus）

2001

Chicken pineal clock genes: Implication of BMAL2 as a bidirectional regulator in circadian clock oscillation

Okano, T., Yamamoto, K., Okano, K., Hirota, T., Kasahara, T., Sasaki, M., Takanaka, Y. & Fukada, Y., 2001 10 4, ： : Genes to Cells. 6, 9, p. 825-836 12 p.

研究成果: Article

73 引用（Scopus）

Chicken pineal Cry genes: Light-dependent up-regulation of cCry1 and cCry2 transcripts

Yamamoto, K., Okano, T. & Fukada, Y., 2001 11 2, ： : Neuroscience Letters. 313, 1-2, p. 13-16 4 p.

研究成果: Article

64 引用（Scopus）

Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: A remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication

Okano, T., Sasaki, M. & Fukada, Y., 2001 3 9, ： : Neuroscience Letters. 300, 2, p. 111-114 4 p.

研究成果: Article

35 引用（Scopus）

Effect of brefeldin A on melatonin secretion of chick pineal cells

Hirota, T., Kagiwada, S., Kasahara, T., Okano, T., Murata, M. & Fukada, Y., 2001 1 1, ： : Journal of biochemistry. 129, 1, p. 51-59 9 p.

研究成果: Article

11 引用（Scopus）

Immunohistochemical localization of opsins and alpha-subunit of transducin in the pineal complex and deep brain of the Japanese grass lizard, Takydromus tachydromoides

Yoshikawa, T., Okano, T., Kokame, K., Hisatomi, O., Tokunaga, F., Oishi, T. & Fukada, Y., 2001 4, ： : Zoological Science. 18, 3, p. 325-330 6 p.

研究成果: Article

5 引用（Scopus）

Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene

Doi, M., Nakajima, Y., Okano, T. & Fukada, Y., 2001, ： : Proceedings of the National Academy of Sciences of the United States of America. 98, 14, p. 8089-8094 6 p.

研究成果: Article

83 引用（Scopus）

Regulatory mechanism for the stability of the meta II intermediate of pinopsin

Nakamura, A., Kojima, D., Okano, T., Imai, H., Terakita, A., Shichida, Y. & Fukada, Y., 2001 2, ： : Journal of biochemistry. 129, 2, p. 329-334 6 p.

研究成果: Article

7 引用（Scopus）

2000

Colocalization of pinopsin with two types of G-protein α-subunits in the chicken pineal gland

Matsushita, A., Yoshikawa, T., Okano, T., Kasahara, T. & Fukada, Y., 2000 1 1, ： : Cell and Tissue Research. 299, 2, p. 245-251 7 p.

研究成果: Article

21 引用（Scopus）

Diversity of opsin immunoreactivities in the extraretinal tissues of four anuran amphibians

Okano, K., Okano, T., Yoshikawa, T., Masuda, A., Fukada, Y. & Oishi, T., 2000 2 1, ： : Journal of Experimental Zoology. 286, 2, p. 136-142 7 p.

研究成果: Article

26 引用（Scopus）

Phototransduction molecules in the pigeon deep brain

Wada, Y., Okano, T. & Fukada, Y., 2000 12 4, ： : Journal of Comparative Neurology. 428, 1, p. 138-144 7 p.

研究成果: Article

31 引用（Scopus）

Rod-type transducin α-subunit mediates a phototransduction pathway in the chicken pineal gland

Kasahara, T., Okano, T., Yoshikawa, T., Yamazaki, K. & Fukada, Y., 2000 7 11, ： : Journal of neurochemistry. 75, 1, p. 217-224 8 p.

研究成果: Article

32 引用（Scopus）

Role of circadian activation of mitogen-activated protein kinase in chick pineal clock oscillation

Sanada, K., Hayashi, Y., Harada, Y., Okano, T. & Fukada, Y., 2000 2 1, ： : Journal of Neuroscience. 20, 3, p. 986-991 6 p.

研究成果: Article

公開

71 引用（Scopus）

1999

Chimeric nature of pinopsin between rod and cone visual pigments

Nakamura, A., Kojima, D., Imai, H., Terakita, A., Okano, T., Shichida, Y. & Fukada, Y., 1999 11 9, ： : Biochemistry. 38, 45, p. 14738-14745 8 p.

研究成果: Article

33 引用（Scopus）

Differentiation of pinopsin-immunoreactive cells in the developing quail pineal organ: An in-vivo and in-vitro immunohistochemical study

Yamao, M., Araki, M., Okano, T., Fukada, Y. & Oishi, T., 1999 6 10, ： : Cell and Tissue Research. 296, 3, p. 667-671 5 p.

研究成果: Article

16 引用（Scopus）

1998

A deep brain photoreceptive molecule in the toad hypothalamus

Yoshikawa, T., Okano, T., Oishi, T. & Fukada, Y., 1998 3 6, ： : FEBS Letters. 424, 1-2, p. 69-72 4 p.

研究成果: Article

48 引用（Scopus）

Identification of rhodopsin in the pigeon deep brain

Wada, Y., Okano, T., Adachi, A., Ebihara, S. & Fukada, Y., 1998 3 6, ： : FEBS Letters. 424, 1-2, p. 53-56 4 p.

研究成果: Article

67 引用（Scopus）

Light-dependent expression of pinopsin gene in chicken pineal gland

Takanaka, Y., Okano, T., Iigo, M. & Fukada, Y., 1998 3, ： : Journal of neurochemistry. 70, 3, p. 908-913 6 p.

研究成果: Article

38 引用（Scopus）

Molecular cloning and characterization of a cDNA encoding the retinal arylalkylamine N-acetyltransferase of the rainbow trout, Oncorhynchus mykiss

Mizusawa, K., Iigo, M., Suetake, H., Yoshiura, Y., Gen, K., Kikuchi, K., Okano, T., Fukada, Y. & Aida, K., 1998 6, ： : Zoological Science. 15, 3, p. 345-351 7 p.

研究成果: Article

14 引用（Scopus）

1997

Immunocytochemical identification of pinopsin in pineal glands of chicken and pigeon

Okano, T., Takanaka, Y., Nakamura, A., Hirunagi, K., Adachi, A., Ebihara, S. & Fukada, Y., 1997 10 15, ： : Molecular Brain Research. 50, 1-2, p. 190-196 7 p.

研究成果: Article

55 引用（Scopus）

Innmunoelectron-microscopic investigation of the subcellular localization of pinopsin in the pineal organ of the chicken

Hirunagi, K., Ebihara, S., Okano, T., Takanaka, Y. & Fukada, Y., 1997 1 1, ： : Cell and Tissue Research. 289, 2, p. 235-241 7 p.

研究成果: Article

22 引用（Scopus）

岡野 俊行

岡野俊行