A case of anorexia nervosa with severe liver dysfunction and pancytopenia

M. Sakuramoto, M. Ohbayashi, M. Shimura, Shinobu Nomura, T. Kuboki, H. Suematsu

研究成果: Article

1 被引用数 (Scopus)

抄録

A 18 year old girl was admitted to our hospital due to anorexia nervosa (AN) in March 1993. She hardly ate anything, and lost her weight from 27.8 kg to 25.8 kg in 10 days. On 15th day, she suffered from severe liver dysfunction due to malnutrition. On 21th day, GOT, GPT, LDH and ALP rose to 4,210 U/l, 2,482 U/l, 2,448 U/l and 1,920 U/l respectively. At the same time she showed pancytopenia. Peripheral WBC and Hb were reduced to 1,400/mm3 and 7.1 g/l respectively, indicating normochromic normocytic anemia. Platelet was also reduced to 2.9 x 104/mm3, but prothrombin time and active partial thromboplastin time were normal. She was treated with mainly intravenous hyperalimentation (IVH), then she recovered after about two months. Thereafter she was treated with combination of behavior therapy and psychotherapy and discharged after five months. AN sometimes complicates liver dysfunction, but a severe case is rare. We investigated some hypotheses of this mechanism referring to previous reports about severe liver dysfunction with AN. And we discussed the relationship between liver dysfunction and pancytopenia.

本文言語English
ページ(範囲)291-296
ページ数6
ジャーナルJapanese Journal of Psychosomatic Medicine
37
4
出版ステータスPublished - 1997
外部発表はい

ASJC Scopus subject areas

  • Psychiatry and Mental health

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