A comparative study on tissue distribution and metabolic adaptation of IMP-GMP 5′-nucleotidase

Roichi Itoh*, Hirotoshi Echizen, Mitsuru Higuchi, Jun Oka, Kouichi Yamada

*この研究の対応する著者

研究成果: Article査読

31 被引用数 (Scopus)

抄録

1. 1. Activity of a cytoplasmic 5′-nucleotidase which preferentially hydrolyzes IMP and GMP (IMP-GMP 5′-nucleotidase) was determined by a specific immunochemical method in two species of birds and two species of mammals. 2. 2. The activity was markedly high in avian liver, and it increased two-fold in response to a high protein diet in chicken liver. 3. 3. In mammals, the activity was high in testis and spleen. In the rat, the activities in liver, kidney and heart extracts increased by about 30% in response to the high protein diet, while they increased three-fold in regenerating liver. 4. 4. Low activities were detected in skeletal muscles and in erythrocytes of all the species studied.

本文言語English
ページ(範囲)153-159
ページ数7
ジャーナルComparative Biochemistry and Physiology -- Part B: Biochemistry and
103
1
DOI
出版ステータスPublished - 1992
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 生理学

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