抜粋
We synthesized a novel cyclooctyne-based clickable fluorescent probe with versatile properties such as high cell-membrane permeability and free diffusibility in the cell. Our probe "FC-DBCO" was conjugated to an azide-modified mannose via a Cu-free click reaction in living HeLa cells and displayed intracellular specific fluorescence imaging with low background signals.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 7879-7882 |
| ページ数 | 4 |
| ジャーナル | Chemical Communications |
| 巻 | 51 |
| 発行部数 | 37 |
| DOI | |
| 出版物ステータス | Published - 2015 5 7 |
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis
- Ceramics and Composites
- Electronic, Optical and Magnetic Materials
- Surfaces, Coatings and Films
- Materials Chemistry
- Metals and Alloys
フィンガープリント A Cu-free clickable fluorescent probe for intracellular targeting of small biomolecules' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。
これを引用
Yamagishi, K., Sawaki, K., Murata, A., & Takeoka, S. (2015). A Cu-free clickable fluorescent probe for intracellular targeting of small biomolecules. Chemical Communications, 51(37), 7879-7882. https://doi.org/10.1039/c4cc09947h