抄録
We synthesized a novel cyclooctyne-based clickable fluorescent probe with versatile properties such as high cell-membrane permeability and free diffusibility in the cell. Our probe "FC-DBCO" was conjugated to an azide-modified mannose via a Cu-free click reaction in living HeLa cells and displayed intracellular specific fluorescence imaging with low background signals.
本文言語 | English |
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ページ(範囲) | 7879-7882 |
ページ数 | 4 |
ジャーナル | Chemical Communications |
巻 | 51 |
号 | 37 |
DOI | |
出版ステータス | Published - 2015 5 7 |
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis
- Ceramics and Composites
- Electronic, Optical and Magnetic Materials
- Surfaces, Coatings and Films
- Materials Chemistry
- Metals and Alloys