@article{f44b7d948f2f4ff0b5e93f47d070614d,
title = "A design for the control of apoptosis in genetically modified Saccharomyces cerevisiae",
abstract = "We have engineered a system that holds potential for use as a safety switch in genetically modified yeasts. Human apoptotic factor BAX (no homolog in yeast), under the control of the FBP1 (gluconeogenesis enzyme) promoter, was conditionally expressed to induce yeast cell apoptosis after glucose depletion. Such systems might prove useful for the safe use of genetically modified organisms.",
keywords = "Apoptosis, Bax, Genetically modified organism (GMO), Gluconeogenesis, Saccharomyces cerevisiae",
author = "Nao Nishida and Misa Noguchi and Kouichi Kuroda and Mitsuyoshi Ueda",
note = "Funding Information: This work was supported by the commission for Development of Artificial Genes Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade, and Industry (METI), Japan. Publisher Copyright: {\textcopyright} 2014 Japan Society for Bioscience, Biotechnology, and Agrochemistry.",
year = "2014",
doi = "10.1080/09168451.2014.878224",
language = "English",
volume = "78",
pages = "358--362",
journal = "Bioscience, Biotechnology and Biochemistry",
issn = "0916-8451",
publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",
number = "2",
}