A novel application of maleimide for advanced drug delivery: In vitro and in vivo evaluation of maleimide-modified pH-sensitive liposomes

Chemical Compounds

• Maleimide 69%
• Liposome 56%
• Drug 32%
• Application 19%
• Cholesterol 18%
• Thiol Group 10%
• Cysteine Residue 10%
• Doxorubicin 10%
• Antitumor 9%
• Glycol 9%
• Zeta Potential 8%
• Encapsulation 8%
• Poly(ethylene Glycol) 8%
• Surface 6%
• Peptide 5%
• Modification 5%
• Amount 4%
• pH Value 4%
• Protein 4%

Medicine & Life Sciences

• maleimide 89%
• Liposomes 60%
• In Vitro Techniques 26%
• Pharmaceutical Preparations 25%
• 1,2-distearoylphosphatidylethanolamine 13%
• Drug Delivery Systems 7%
• colfosceril palmitate 6%
• phosphorylethanolamine 5%
• Cholesterol 5%
• Ethylene Glycol 4%
• Polyethylene Glycols 4%
• Sulfhydryl Compounds 4%
• Subcutaneous Injections 3%
• Cysteine 3%
• Doxorubicin 3%
• Glutamic Acid 3%
• Breast Neoplasms 2%
• Peptides 2%
• Injections 2%
• Proteins 1%

Engineering & Materials Science

• Liposomes 100%
• Drug delivery 81%
• Cholesterol 11%
• Drug Delivery Systems 11%
• Polyethylene glycols 9%
• Molar ratio 9%
• Cytotoxicity 5%
• Zeta potential 5%
• Peptides 5%
• Encapsulation 4%
• Imaging systems 4%
• Proteins 3%
• Tissue 3%