A novel indole-diterpenoid, JBIR-03 with anti-MRSA activity from Dichotomomyces cejpii var. cejpii NBRC 103559

Masahiro Ogata, Jun Ya Ueda, Midori Hoshi, Junko Hashimoto, Takuji Nakashima, Kozue Anzai, Motoki Takagi, Kazuo Shin-Ya

研究成果: Article査読

32 被引用数 (Scopus)

抄録

A new indole-diterpene, JBIR-03 (1), was isolated from the fungus Dichotomomyces cejpii var. cejpii NBRC 103559 and its structure was determined based on the spectroscopic data. 1 exhibited anti-MRSA (methicillin-resistant Staphylococcus aureus) activity and antifungal activity against apple Valsa canker-causing fungus, Valsa ceratosperma, while it exhibited no toxicity towards human cancer cells.

本文言語English
ページ(範囲)645-648
ページ数4
ジャーナルJournal of Antibiotics
60
10
DOI
出版ステータスPublished - 2007 10
外部発表はい

ASJC Scopus subject areas

  • 薬理学
  • 創薬

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