A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Mitsumasa Homma; Yoshiaki Takei; Atsushi Murata; Takafumi Inoue; Shinji Takeoka

doi:10.1039/c4cc10349a

A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Mitsumasa Homma, Yoshiaki Takei, Atsushi Murata, Takafumi Inoue, Shinji Takeoka

研究成果: Article › 査読

62 被引用数 (Scopus)

抄録

Mitochondrial thermodynamics is the key to understand cellular activities related to homeostasis and energy balance. Here, we report the first ratiometric fluorescent molecular probe (Mito-RTP) that is selectively localized in the mitochondria and visualize the temperature. We confirmed that Mito-RTP could work as a ratiometric thermometer in a cuvette and living cells.

本文言語	English
ページ（範囲）	6194-6197
ページ数	4
ジャーナル	Chemical Communications
巻	51
号	28
DOI	https://doi.org/10.1039/c4cc10349a
出版ステータス	Published - 2015 4 11

ASJC Scopus subject areas

Chemistry(all)
Catalysis
Ceramics and Composites
Electronic, Optical and Magnetic Materials
Surfaces, Coatings and Films
Materials Chemistry
Metals and Alloys

文献へのアクセス

10.1039/c4cc10349a

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引用スタイル

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