A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Mitsumasa Homma; Yoshiaki Takei; Atsushi Murata; Takafumi Inoue; Shinji Takeoka

doi:10.1039/c4cc10349a

A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Mitsumasa Homma, Yoshiaki Takei, Atsushi Murata, Takafumi Inoue, Shinji Takeoka^*

^*この研究の対応する著者

先進理工学部

研究成果 › 査読

78 被引用数 (Scopus)

抄録

Mitochondrial thermodynamics is the key to understand cellular activities related to homeostasis and energy balance. Here, we report the first ratiometric fluorescent molecular probe (Mito-RTP) that is selectively localized in the mitochondria and visualize the temperature. We confirmed that Mito-RTP could work as a ratiometric thermometer in a cuvette and living cells.

本文言語	English
ページ（範囲）	6194-6197
ページ数	4
ジャーナル	Chemical Communications
巻	51
号	28
DOI	https://doi.org/10.1039/c4cc10349a
出版ステータス	Published - 2015 4 11

ASJC Scopus subject areas

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学 (全般)
表面、皮膜および薄膜
金属および合金
材料化学

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AU - Takeoka, Shinji

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A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

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