A study of magnetic drug delivery system using bulk high temperature superconducting magnet

Shigehiro Nishijima*, Shin Ichi Takeda, Fumihito Mishima, Yasuhiko Tabata, Masaya Yamamoto, Jun Ichiro Joh, Hiroshi Iseki, Yoshihiro Muragaki, Akira Sasaki, Jun Kubota, Norihide Saho

*この研究の対応する著者

研究成果: Article査読

34 被引用数 (Scopus)

抄録

A magnetic drug delivery system (MDDS) has been studied to navigate and/or accumulate the magnetic seeded drug at a local diseased part in the human body. The bulk high temperature superconductors (HTS) are employed to control the drug because they would produce the required magnetic fields for MDDS. The trajectory of the ferromagnetic particles in the blood vessel was calculated and the possibility of the navigation of the drug is discussed. In the experiment the HTS (GdBaCuO) which produces the magnetic field of 4.5 T at the surface, was located 25 mm apart from the Y-shaped blood vessel. The drug navigation probability to the desired direction was confirmed to be higher than 80%. A rat experiment was also performed successfully using a permanent magnet. The possible MDDS system will be discussed.

本文言語English
論文番号4517321
ページ(範囲)874-877
ページ数4
ジャーナルIEEE Transactions on Applied Superconductivity
18
2
DOI
出版ステータスPublished - 2008 6月
外部発表はい

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • 電子工学および電気工学

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