A TEMPO-conjugated fluorescent probe for monitoring mitochondrial redox reactions

Shota Hirosawa, Satoshi Arai, Shinji Takeoka

研究成果: Article

41 引用 (Scopus)

抜粋

We report a mitochondrial targeted redox probe (MitoRP) that comprises a nitroxide radical (TEMPO) moiety and coumarin 343. Using isolated mitochondria in the presence/absence of substrates and inhibitors of oxidative phosphorylation, we demonstrated that MitoRP is a useful probe to monitor the electron flow associated with complex I.

元の言語English
ページ(範囲)4845-4847
ページ数3
ジャーナルChemical Communications
48
発行部数40
DOI
出版物ステータスPublished - 2012 4 23

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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