Accuracy in Pinch Force Control Can Be Altered by Static Magnetic Field Stimulation Over the Primary Motor Cortex

Kento Nakagawa, Atsushi Sasaki, Kimitaka Nakazawa

研究成果: Article

抄録

Objective: Transcranial static magnetic field stimulation (tSMS) has recently been demonstrated to modulate cortical excitability and perceptual functions in humans, however, the effect of tSMS on motor behavior is still unknown. We investigated whether tSMS over the primary motor cortex (M1) alters voluntary ballistic force control. Materials and Methods: Twenty healthy participants performed ballistic pinch contractions in both hands alternatively at a predetermined submaximal force level and without visual feedback, before, during and after tSMS and sham interventions. A compact magnet for tSMS and a stainless steel cylinder for sham stimulation were positioned over the either right or left M1 for 15 min. Results: The absolute error to the target force level was significantly larger for the tSMS-intervened hand than for the sham-intervened hands during and after intervention (p < 0.05, respectively). Compared with the preintervention session, the absolute error increased in the tSMS-intervened hand during and after intervention (p < 0.05, respectively), but not in the sham-intervened hand. Conclusions: tSMS over M1 can impair the accuracy of submaximal ballistic pinch force control. This suggests that tSMS is strong enough to alter motor behavior in humans.

元の言語English
ジャーナルNeuromodulation
DOI
出版物ステータスAccepted/In press - 2019 1 1
外部発表Yes

Fingerprint

Motor Cortex
Magnetic Fields
Hand
Sensory Feedback
Magnets
Stainless Steel
Healthy Volunteers

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine

これを引用

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title = "Accuracy in Pinch Force Control Can Be Altered by Static Magnetic Field Stimulation Over the Primary Motor Cortex",
abstract = "Objective: Transcranial static magnetic field stimulation (tSMS) has recently been demonstrated to modulate cortical excitability and perceptual functions in humans, however, the effect of tSMS on motor behavior is still unknown. We investigated whether tSMS over the primary motor cortex (M1) alters voluntary ballistic force control. Materials and Methods: Twenty healthy participants performed ballistic pinch contractions in both hands alternatively at a predetermined submaximal force level and without visual feedback, before, during and after tSMS and sham interventions. A compact magnet for tSMS and a stainless steel cylinder for sham stimulation were positioned over the either right or left M1 for 15 min. Results: The absolute error to the target force level was significantly larger for the tSMS-intervened hand than for the sham-intervened hands during and after intervention (p < 0.05, respectively). Compared with the preintervention session, the absolute error increased in the tSMS-intervened hand during and after intervention (p < 0.05, respectively), but not in the sham-intervened hand. Conclusions: tSMS over M1 can impair the accuracy of submaximal ballistic pinch force control. This suggests that tSMS is strong enough to alter motor behavior in humans.",
keywords = "Force control, primary motor cortex, transcranial static magnetic field stimulation",
author = "Kento Nakagawa and Atsushi Sasaki and Kimitaka Nakazawa",
year = "2019",
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doi = "10.1111/ner.12912",
language = "English",
journal = "Neuromodulation",
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TY - JOUR

T1 - Accuracy in Pinch Force Control Can Be Altered by Static Magnetic Field Stimulation Over the Primary Motor Cortex

AU - Nakagawa, Kento

AU - Sasaki, Atsushi

AU - Nakazawa, Kimitaka

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objective: Transcranial static magnetic field stimulation (tSMS) has recently been demonstrated to modulate cortical excitability and perceptual functions in humans, however, the effect of tSMS on motor behavior is still unknown. We investigated whether tSMS over the primary motor cortex (M1) alters voluntary ballistic force control. Materials and Methods: Twenty healthy participants performed ballistic pinch contractions in both hands alternatively at a predetermined submaximal force level and without visual feedback, before, during and after tSMS and sham interventions. A compact magnet for tSMS and a stainless steel cylinder for sham stimulation were positioned over the either right or left M1 for 15 min. Results: The absolute error to the target force level was significantly larger for the tSMS-intervened hand than for the sham-intervened hands during and after intervention (p < 0.05, respectively). Compared with the preintervention session, the absolute error increased in the tSMS-intervened hand during and after intervention (p < 0.05, respectively), but not in the sham-intervened hand. Conclusions: tSMS over M1 can impair the accuracy of submaximal ballistic pinch force control. This suggests that tSMS is strong enough to alter motor behavior in humans.

AB - Objective: Transcranial static magnetic field stimulation (tSMS) has recently been demonstrated to modulate cortical excitability and perceptual functions in humans, however, the effect of tSMS on motor behavior is still unknown. We investigated whether tSMS over the primary motor cortex (M1) alters voluntary ballistic force control. Materials and Methods: Twenty healthy participants performed ballistic pinch contractions in both hands alternatively at a predetermined submaximal force level and without visual feedback, before, during and after tSMS and sham interventions. A compact magnet for tSMS and a stainless steel cylinder for sham stimulation were positioned over the either right or left M1 for 15 min. Results: The absolute error to the target force level was significantly larger for the tSMS-intervened hand than for the sham-intervened hands during and after intervention (p < 0.05, respectively). Compared with the preintervention session, the absolute error increased in the tSMS-intervened hand during and after intervention (p < 0.05, respectively), but not in the sham-intervened hand. Conclusions: tSMS over M1 can impair the accuracy of submaximal ballistic pinch force control. This suggests that tSMS is strong enough to alter motor behavior in humans.

KW - Force control

KW - primary motor cortex

KW - transcranial static magnetic field stimulation

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