Achievement of peristaltic design in the artificial esophagus based on esophageal characteristic analysis of goats’ specimen

Yasunori Taira, K. Kamiya, Y. Shiraishi, H. Miura, T. Shiga, M. O. Hashem, A. Yamada, Y. Tsuboko, T. Ito, K. Sano, D. Homma, T. Yambe

研究成果: Conference contribution

抄録

In order to promote activity of daily life of patients with severe esophageal diseases, supporting peristalsis motion at the esophagus might be efficient. So we have been developing an artificial esophagus (AE) which has peristalsis motion function, and we have achieved the AE by using Ni-Ti shape memory alloy fibers. We extracted the esophagus from the epiglottis to the cardia potion from goats, which weighed 48.6±16.3 kg (n=4), after the animal experiment procedures. Prior to the measurement of characteristics of natural esophagus, we defined 5 segments in each extracted esophagus. Then we set the specimen in the static characteristic test apparatus in which we could measure segmental pressure-volume relations. Pressure and volume were measured simultaneously. All these measurement were performed within 3 hours from the extraction. Average length of each esophagus was 63±7cm. Because of the proximal segment of the specimen exhibited that the steeper increase of pressure than the distal portion near the cardia, we characterized that the distal esophagus is firmer than proximal. The proximal segment exhibited 55% bigger increase in pressure than the distal portion near the gastric cardiac part. Therefore it was suggested that compliance at the proximal portion could be lower at the small amount of internal volume. On the other hands, the extensibility of distal esophagus might be bigger than that at proximal segment. Consequently it was indicated that a new mechanical structure could be applied for the development of AE which could reproduce peristaltic motions.

本文言語English
ホスト出版物のタイトルThe 15th International Conference on Biomedical Engineering, ICBME 2013
編集者James Goh
出版社Springer Verlag
ページ372-374
ページ数3
ISBN(電子版)9783319029122
DOI
出版ステータスPublished - 2014
外部発表はい
イベント15th International Conference on Biomedical Engineering, ICBME 2013 - Singapore, Singapore
継続期間: 2013 12 42013 12 7

出版物シリーズ

名前IFMBE Proceedings
43
ISSN(印刷版)1680-0737

Other

Other15th International Conference on Biomedical Engineering, ICBME 2013
CountrySingapore
CitySingapore
Period13/12/413/12/7

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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