抄録
Chiral crystals of the only achiral proteinogenic α-amino acid, glycine induced the asymmetric autocatalysis with amplification of enantiomeric excess (ee). The P3 1 crystals of γ-glycine, which display positive Cotton effect (CD) at around 215 nm, mediate the asymmetric autocatalysis to yield (R)-pyrimidyl alkanol with high ee. In contrast, the enantiomorphic P3 2 crystals, which display negative Cotton effect, afford (S)-alkanol after the significant amplification of ee by asymmetric autocatalysis.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 4200-4203 |
| ページ数 | 4 |
| ジャーナル | Organic and Biomolecular Chemistry |
| 巻 | 17 |
| 発行部数 | 17 |
| DOI | |
| 出版物ステータス | Published - 2019 1 1 |
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ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
これを引用
Achiral amino acid glycine acts as an origin of homochirality in asymmetric autocatalysis. / Matsumoto, Arimasa; Ozaki, Hanae; Tsuchiya, Sumeru; Asahi, Toru; Lahav, Meir; Kawasaki, Tsuneomi; Soai, Kenso.
：: Organic and Biomolecular Chemistry, 巻 17, 番号 17, 01.01.2019, p. 4200-4203.研究成果: Article
}
TY - JOUR
T1 - Achiral amino acid glycine acts as an origin of homochirality in asymmetric autocatalysis
AU - Matsumoto, Arimasa
AU - Ozaki, Hanae
AU - Tsuchiya, Sumeru
AU - Asahi, Toru
AU - Lahav, Meir
AU - Kawasaki, Tsuneomi
AU - Soai, Kenso
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Chiral crystals of the only achiral proteinogenic α-amino acid, glycine induced the asymmetric autocatalysis with amplification of enantiomeric excess (ee). The P3 1 crystals of γ-glycine, which display positive Cotton effect (CD) at around 215 nm, mediate the asymmetric autocatalysis to yield (R)-pyrimidyl alkanol with high ee. In contrast, the enantiomorphic P3 2 crystals, which display negative Cotton effect, afford (S)-alkanol after the significant amplification of ee by asymmetric autocatalysis.
AB - Chiral crystals of the only achiral proteinogenic α-amino acid, glycine induced the asymmetric autocatalysis with amplification of enantiomeric excess (ee). The P3 1 crystals of γ-glycine, which display positive Cotton effect (CD) at around 215 nm, mediate the asymmetric autocatalysis to yield (R)-pyrimidyl alkanol with high ee. In contrast, the enantiomorphic P3 2 crystals, which display negative Cotton effect, afford (S)-alkanol after the significant amplification of ee by asymmetric autocatalysis.
UR - http://www.scopus.com/inward/record.url?scp=85065150968&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065150968&partnerID=8YFLogxK
U2 - 10.1039/c9ob00345b
DO - 10.1039/c9ob00345b
M3 - Article
C2 - 30932119
AN - SCOPUS:85065150968
VL - 17
SP - 4200
EP - 4203
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 17
ER -