Actinomycins produced by streptomyces lichenis lcr6-01t and its antibacterial activity

Pawina Kanchanasin, Patcharin Saeng-In, Takuji Nakashima, Hirotaka Matsuo, Yōko Takahashi, Somboon Tanasupawat*

*この研究の対応する著者

研究成果: Article査読

抄録

A new actinomycete species, Streptomyces lichenis LCR6-01T was isolated from lichen collected in Chiang Rai province, Thailand. On the course of screening for antimicrobial activity, the culture broth of strain LCR6-01T exhibited antibacterial activity against Bacillus subtilis ATCC 6633, Kocuria rhizophila ATCC 9341, Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 (inhibition zone 14.7 ± 0.6-23.0 ± 0.9 mm). The culture extracts analyzed by liquid chromatographyelectrospray ionization-mass spectrometry (LC-ESI-MS) and the physicochemical properties of secondary metabolites were searched in database. The antibacterial agents were detected as actinomycins which contained 3 analogs of Au7a, D, and D 43β.

本文言語English
ページ(範囲)864-871
ページ数8
ジャーナルChiang Mai Journal of Science
47
5
出版ステータスPublished - 2020 9
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)
  • 数学 (全般)
  • 材料科学(全般)
  • 生化学、遺伝学、分子生物学(全般)
  • 物理学および天文学(全般)

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