Acute Exercise and Appetite-Regulating Hormones in Overweight and Obese Individuals: A Meta-Analysis

Jessica Anne Douglas*, Kevin Deighton, Jan Maria Atkinson, Vahid Sari-Sarraf, David John Stensel, Greg Atkinson

*この研究の対応する著者

研究成果: Review article査読

8 被引用数 (Scopus)

抄録

In lean individuals, acute aerobic exercise is reported to transiently suppress sensations of appetite, suppress blood concentrations of acylated ghrelin (AG), and increase glucagon-like peptide-1 (GLP-1) and peptide-YY (PYY). Findings in overweight/obese individuals have yet to be synthesised. In this systematic review and meta-analysis, we quantified the effects that acute exercise has on AG and total PYY and GLP-1 in overweight/obese individuals. The potential for body mass index (BMI) to act as a moderator for AG was also explored. Six published studies (73 participants, 78% male, mean BMI: 30.6 kg·m-2) met the inclusion criteria. Standardised mean differences (SMDs) and standard errors were extracted for AG and total PYY and GLP-1 concentrations in control and exercise trials and synthesised using a random effects meta-analysis model. BMI was the predictor in metaregression for AG. Exercise moderately suppressed AG area-under-the-curve concentrations (pooled SMD:-0.34, 95% CI:-0.53 to-0.15). The magnitude of this reduction was greater for higher mean BMIs (pooled metaregression slope:-0.04 SMD/kg·m-2 (95% CI:-0.07 to 0.00)). Trivial SMDs were obtained for total PYY (0.10, 95% CI:-0.13 to 0.31) and GLP-1 (-0.03, 95% CI:-0.18 to 0.13). This indicates that exercise in overweight/obese individuals moderately alters AG in a direction that could be associated with decreased hunger and energy intake. This trial is registered with PROSPERO: CRD42014006265.

本文言語English
論文番号2643625
ジャーナルJournal of Obesity
2016
DOI
出版ステータスPublished - 2016
外部発表はい

ASJC Scopus subject areas

  • 内分泌学、糖尿病および代謝内科学

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