Adsorption of bovine serum albumin to a polymer brush prepared by atom-transfer radical polymerization in a porous inorganic membrane

Hidetaka Kawakita*, Hiroyasu Masunaga, Kanako Nomura, Kazuya Uezu, Isamu Akiba, Satoshi Tsuneda

*この研究の対応する著者

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Protein adsorption was performed by a polymer brush prepared by atom-transfer radical polymerization (ATRP) to a porous inorganic membrane. The porous inorganic membrane, Shirasu Porous Glass made from silica, was modified with a halogen-containing compound to bind the active species for the polymerization. Glycidyl methacrylate was polymerized from the halogen compound by ATRP for a prescribed time, and subsequently chemically modified. The progression of the chemical modification allowed the membrane to lower the phosphate-buffer flux of the porous membrane due to the attachment of the polymer brush. Bovine serum albumin (BSA), as a model protein, was adsorbed at 12 mg per gram of the membrane in permeating BSA solution through the polymer-brush-attached porous membrane.

本文言語English
ページ(範囲)387-391
ページ数5
ジャーナルJournal of Porous Materials
14
4
DOI
出版ステータスPublished - 2007 11

ASJC Scopus subject areas

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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