Aerobic exercise training increases cerebral blood flow in postmenopausal women

Nobuhiko Akazawa, Youngju Choi, Asako Miyaki, Jun Sugawara, Ryuichi Ajisaka, Seiji Maeda*

*この研究の対応する著者

研究成果査読

10 被引用数 (Scopus)

抄録

Background: Age-related decrease in cerebral blood flow is a risk factor for cognitive decline. Aerobic exercise training improves vascular and cognitive functions. However, the effect of exercise training on age-related reduction in cerebral blood flow is unclear. The present study investigated whether aerobic exercise training can increase cerebral blood flow in postmenopausal women. Methods: Twenty healthy postmenopausal women were assigned to either the exercise training group (n = 10) or the control group (n = 10). The exercise group completed 8 weeks of moderate aerobic exercise intervention. The control group did not change their physical activity level. Before and after each intervention, middle cerebral blood flow velocity and cerebrovascular resistance were measured using transcranial Doppler ultrasonography. Results: The baseline middle cerebral blood flow velocity, cerebrovascular resistance, and most other key dependent variables did not significantly differ between the groups. Aerobic exercise training significantly increased middle cerebral blood flow velocity and significantly decreased cerebrovascular resistance, whereas no such changes were observed in the control group. Conclusions: We showed that aerobic exercise training increased middle cerebral blood flow velocity and decreased cerebrovascular resistance in postmenopausal women. The results of the current study suggest that regular aerobic exercise may attenuate aging-induced decrease in cerebral blood flow.

本文言語English
ページ(範囲)124-129
ページ数6
ジャーナルArtery Research
6
3
DOI
出版ステータスPublished - 2012 9
外部発表はい

ASJC Scopus subject areas

  • 解剖学
  • 循環器および心血管医学
  • 生理学(医学)

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