Ageing affects the association between serum 25- hydroxyvitamin D concentrations and cardiorespiratory fitness in middle-aged and elderly men

Xiaomin Sun, Tanisawa Kumpei, Tomoko Ito, Satomi Oshima, Mitsuru Higuchi, Zhen Bo Cao

研究成果: Article査読

抄録

The studies investigated the association between serum 25 hydroxyvitamin D (25(OH)D) concentrations and cardiorespiratory fitness (CRF) are few, and the results are controversial. We aim to evaluate the association of serum 25(OH)D concentrations with CRF in adults, and assess whether the associations vary with ageing. Methods and Study Design: The study included 78 middle-aged (30-64 years) and 83 elderly (65-79 years) Japanese men. Hand grip strength and leg extension power were measured using hand grip and leg dynamometers, respectively. CRF was measured via a maximal graded exercise test and quantified as the peak oxygen uptake (VO2peak). Fasting serum 25(OH)D concentrations were determined by enzyme-linked immunosorbant assay. Results: Serum 25(OH)D concentrations were positively related to hand grip strength (r=0.331, p<0.001), leg extension power (r=0.353, p<0.001), CRF (r=0.285, p<0.001) in all adults after adjustment for age. Significant interaction between 25(OH)D and age on CRF was observed (p<0.05). Age related reduction of CRF was prevented in high 25(OH)D group (p<0.05). In the elderly, subjects in high 25(OH)D group had higher CRF compared with those in low group (p<0.05).(p<0.05).

本文言語English
ページ(範囲)614-620
ページ数7
ジャーナルAsia Pacific journal of clinical nutrition
28
3
DOI
出版ステータスPublished - 2019 9

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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