Alkylation of pyridine-3,5-dicarboxamide and pyridine-3,5-dicarbonitriles by radical substitution

Nobuhiro Kanomata, Hisashi Nagahara, Masaru Tada

    研究成果: Article

    4 引用 (Scopus)

    抄録

    Structural modification of NAD(P) model compounds, N,N,N′,N′ tetramethylpyridine-3,5-dicarboxamide (1), pyridine-3,5-dicarbonitrile (2), and 4-methylpyridine-3,5-dicarbonitrile (3), have been explored by the reaction with alkyl radicals such as the 1-adamantyl, tert-butyi, and isopropyl radicals. The alkyl substitutions of compounds 1, 2, and 3 with the 1-adamantyl and the fert-butyl radical gave both 2-mono and 2,6-disubsti-tution products, whereas the reaction of compound 2 with the isopropyl radical gave 2-mono 6c, 2,4-di 7c, 2,6-di 8c, and 2,4,6-trisubstitution 9c products.

    元の言語English
    ページ(範囲)1567-1571
    ページ数5
    ジャーナルMathematical Problems in Engineering
    29
    発行部数6
    出版物ステータスPublished - 1992 10 1

    Fingerprint

    Alkylation
    Pyridine
    Substitution
    Substitution reactions
    Model

    ASJC Scopus subject areas

    • Mathematics(all)
    • Engineering(all)

    これを引用

    Alkylation of pyridine-3,5-dicarboxamide and pyridine-3,5-dicarbonitriles by radical substitution. / Kanomata, Nobuhiro; Nagahara, Hisashi; Tada, Masaru.

    :: Mathematical Problems in Engineering, 巻 29, 番号 6, 01.10.1992, p. 1567-1571.

    研究成果: Article

    @article{ab7c30c5bed04498b89050dc17cea38c,
    title = "Alkylation of pyridine-3,5-dicarboxamide and pyridine-3,5-dicarbonitriles by radical substitution",
    abstract = "Structural modification of NAD(P) model compounds, N,N,N′,N′ tetramethylpyridine-3,5-dicarboxamide (1), pyridine-3,5-dicarbonitrile (2), and 4-methylpyridine-3,5-dicarbonitrile (3), have been explored by the reaction with alkyl radicals such as the 1-adamantyl, tert-butyi, and isopropyl radicals. The alkyl substitutions of compounds 1, 2, and 3 with the 1-adamantyl and the fert-butyl radical gave both 2-mono and 2,6-disubsti-tution products, whereas the reaction of compound 2 with the isopropyl radical gave 2-mono 6c, 2,4-di 7c, 2,6-di 8c, and 2,4,6-trisubstitution 9c products.",
    author = "Nobuhiro Kanomata and Hisashi Nagahara and Masaru Tada",
    year = "1992",
    month = "10",
    day = "1",
    language = "English",
    volume = "29",
    pages = "1567--1571",
    journal = "Mathematical Problems in Engineering",
    issn = "1024-123X",
    publisher = "Hindawi Publishing Corporation",
    number = "6",

    }

    TY - JOUR

    T1 - Alkylation of pyridine-3,5-dicarboxamide and pyridine-3,5-dicarbonitriles by radical substitution

    AU - Kanomata, Nobuhiro

    AU - Nagahara, Hisashi

    AU - Tada, Masaru

    PY - 1992/10/1

    Y1 - 1992/10/1

    N2 - Structural modification of NAD(P) model compounds, N,N,N′,N′ tetramethylpyridine-3,5-dicarboxamide (1), pyridine-3,5-dicarbonitrile (2), and 4-methylpyridine-3,5-dicarbonitrile (3), have been explored by the reaction with alkyl radicals such as the 1-adamantyl, tert-butyi, and isopropyl radicals. The alkyl substitutions of compounds 1, 2, and 3 with the 1-adamantyl and the fert-butyl radical gave both 2-mono and 2,6-disubsti-tution products, whereas the reaction of compound 2 with the isopropyl radical gave 2-mono 6c, 2,4-di 7c, 2,6-di 8c, and 2,4,6-trisubstitution 9c products.

    AB - Structural modification of NAD(P) model compounds, N,N,N′,N′ tetramethylpyridine-3,5-dicarboxamide (1), pyridine-3,5-dicarbonitrile (2), and 4-methylpyridine-3,5-dicarbonitrile (3), have been explored by the reaction with alkyl radicals such as the 1-adamantyl, tert-butyi, and isopropyl radicals. The alkyl substitutions of compounds 1, 2, and 3 with the 1-adamantyl and the fert-butyl radical gave both 2-mono and 2,6-disubsti-tution products, whereas the reaction of compound 2 with the isopropyl radical gave 2-mono 6c, 2,4-di 7c, 2,6-di 8c, and 2,4,6-trisubstitution 9c products.

    UR - http://www.scopus.com/inward/record.url?scp=84920778474&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84920778474&partnerID=8YFLogxK

    M3 - Article

    AN - SCOPUS:84920778474

    VL - 29

    SP - 1567

    EP - 1571

    JO - Mathematical Problems in Engineering

    JF - Mathematical Problems in Engineering

    SN - 1024-123X

    IS - 6

    ER -