Alterations of immunoreactive beta-endorphin in the third ventricular fluid in response to electrical stimulation of the human periaqueductal gray matter

K. Amano, K. Kitamura, H. Kawamura, T. Tanikawa, H. Kawabatake, M. Notani, Hiroshi Iseki, T. Shiwaku, T. Suda, H. Demura

研究成果: Article

抄録

Immunoreactive beta-endorphin in the third ventricular fluid was measured in response to electrical stimulation of the periaqueductal gray matter in 8 patients with intractable pain during rostral mesencephalic reticulotomy for pain relief. In all patients, marked increase of immunoreactive beta-endorphin was observed. On the other hand, in cases of electrical stimulation of the zona incerta performed during stereoencephalotomy, in 5 patients with involuntary movement, immunoreactive beta-endorphin in the third ventricular fluid did not show any significant change. The authors conclude that the increase of immunoreactive beta-endorphin on electrical stimulation of the periaqueductal gray matter is not a nonspecific response to brain stimulation but a specific response in regard to cerebral localization of endorphin. Direct correlation between pain relief and periaqueductal gray stimulation is also questioned.

元の言語English
ページ(範囲)150-158
ページ数9
ジャーナルApplied Neurophysiology
43
発行部数3-5
出版物ステータスPublished - 1980
外部発表Yes

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Periaqueductal Gray
beta-Endorphin
Electric Stimulation
Endorphins
Pain
Intractable Pain
Dyskinesias
Brain

ASJC Scopus subject areas

  • Clinical Neurology

これを引用

Amano, K., Kitamura, K., Kawamura, H., Tanikawa, T., Kawabatake, H., Notani, M., ... Demura, H. (1980). Alterations of immunoreactive beta-endorphin in the third ventricular fluid in response to electrical stimulation of the human periaqueductal gray matter. Applied Neurophysiology, 43(3-5), 150-158.

Alterations of immunoreactive beta-endorphin in the third ventricular fluid in response to electrical stimulation of the human periaqueductal gray matter. / Amano, K.; Kitamura, K.; Kawamura, H.; Tanikawa, T.; Kawabatake, H.; Notani, M.; Iseki, Hiroshi; Shiwaku, T.; Suda, T.; Demura, H.

:: Applied Neurophysiology, 巻 43, 番号 3-5, 1980, p. 150-158.

研究成果: Article

Amano, K, Kitamura, K, Kawamura, H, Tanikawa, T, Kawabatake, H, Notani, M, Iseki, H, Shiwaku, T, Suda, T & Demura, H 1980, 'Alterations of immunoreactive beta-endorphin in the third ventricular fluid in response to electrical stimulation of the human periaqueductal gray matter', Applied Neurophysiology, 巻. 43, 番号 3-5, pp. 150-158.
Amano, K. ; Kitamura, K. ; Kawamura, H. ; Tanikawa, T. ; Kawabatake, H. ; Notani, M. ; Iseki, Hiroshi ; Shiwaku, T. ; Suda, T. ; Demura, H. / Alterations of immunoreactive beta-endorphin in the third ventricular fluid in response to electrical stimulation of the human periaqueductal gray matter. :: Applied Neurophysiology. 1980 ; 巻 43, 番号 3-5. pp. 150-158.
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AU - Kitamura, K.

AU - Kawamura, H.

AU - Tanikawa, T.

AU - Kawabatake, H.

AU - Notani, M.

AU - Iseki, Hiroshi

AU - Shiwaku, T.

AU - Suda, T.

AU - Demura, H.

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