Amphibian prolactins: Activity in the eft skin transepithelial potential bioassay

Stephen C. Brown, Patricia Stocking Brown, Kazutoshi Yamamoto, Kouhei Matsuda, Sakae Kikuyama

    研究成果: Article査読

    13 被引用数 (Scopus)

    抄録

    The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.

    本文言語English
    ページ(範囲)1-7
    ページ数7
    ジャーナルGeneral and Comparative Endocrinology
    82
    1
    DOI
    出版ステータスPublished - 1991

    ASJC Scopus subject areas

    • Endocrinology

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