Analysis of histone modifications in neural cells as an example of orexin neurons

Koji Hayakawa, Chikako Yoneda, Ruiko Tani, Kunio Shiota

研究成果: Chapter

抄録

Epigenetic regulation, which causes structural changes in chromatin in a locus-specific and/or genome-wide manner, is the basic mechanism for embryonic development, cellular differentiation, and maintenance of cellular function. Histone modifications, together with DNA methylation, represent the major epigenetic events. Here, we describe a chromatin immunoprecipitation (ChIP) method for the analysis of histone modifications, taking a study of orexin neurons as an example. This method can be used in basic and applied neurobiology.

本文言語English
ホスト出版物のタイトルNeuromethods
出版社Humana Press Inc.
ページ139-147
ページ数9
105
DOI
出版ステータスPublished - 2016
外部発表はい

出版物シリーズ

名前Neuromethods
105
ISSN(印刷版)08932336
ISSN(電子版)19406045

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Neuroscience(all)
  • Psychiatry and Mental health

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