Analysis of tissue-specific DNA methylation during development.

Jun Ohgane, Naka Hattori, Kunio Shiota

研究成果: Article査読

3 被引用数 (Scopus)

抄録

The establishment of a cell identification method more accurate than the conventional morphological and cell-type-specific marker analyses has been desired. DNA methylation is related to the gene activity including gene-silencing and is a key mechanism of epigenetics underling cellular differentiaion and development in mammals. Recent studies indicated that there exist unique genomic DNA methylation profiles specific to the cell type. DNA methylation profiles a mechanism for memorizing the set of genes inherent in individual type of cells. In this chapter, we present the methods to analyze DNA methylation status for identifying cells or tissues.

本文言語English
ページ(範囲)371-382
ページ数12
ジャーナルMethods in molecular biology (Clifton, N.J.)
289
出版ステータスPublished - 2005
外部発表はい

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

フィンガープリント 「Analysis of tissue-specific DNA methylation during development.」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル