抄録
Ancorinosides B-D were isolated from the marine sponge Penares sollasi Thiele as inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).1 Their structures were elucidated to be tetramic acid glycosides related to ancorinoside A by spectroscopic and chemical methods. Ancorinosides B-D inhibited MT1-MMP with IC50 values of 180-500 μg/mL.
元の言語 | English |
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ページ(範囲) | 1229-1234 |
ページ数 | 6 |
ジャーナル | Tetrahedron |
巻 | 57 |
発行部数 | 7 |
DOI | |
出版物ステータス | Published - 2001 2 11 |
外部発表 | Yes |
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ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
これを引用
Ancorinosides B-D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele. / Fujita, Masaki; Nakao, Youichi; Matsunaga, Shigeki; Seiki, Motoharu; Itoh, Yoshifumi; Van Soest, Rob W M; Fusetani, Nobuhiro.
:: Tetrahedron, 巻 57, 番号 7, 11.02.2001, p. 1229-1234.研究成果: Article
}
TY - JOUR
T1 - Ancorinosides B-D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele
AU - Fujita, Masaki
AU - Nakao, Youichi
AU - Matsunaga, Shigeki
AU - Seiki, Motoharu
AU - Itoh, Yoshifumi
AU - Van Soest, Rob W M
AU - Fusetani, Nobuhiro
PY - 2001/2/11
Y1 - 2001/2/11
N2 - Ancorinosides B-D were isolated from the marine sponge Penares sollasi Thiele as inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).1 Their structures were elucidated to be tetramic acid glycosides related to ancorinoside A by spectroscopic and chemical methods. Ancorinosides B-D inhibited MT1-MMP with IC50 values of 180-500 μg/mL.
AB - Ancorinosides B-D were isolated from the marine sponge Penares sollasi Thiele as inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).1 Their structures were elucidated to be tetramic acid glycosides related to ancorinoside A by spectroscopic and chemical methods. Ancorinosides B-D inhibited MT1-MMP with IC50 values of 180-500 μg/mL.
KW - Biologically active compounds
KW - Enzyme inhibitors
KW - Marine metabolites
KW - Sponges
UR - http://www.scopus.com/inward/record.url?scp=0035843357&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035843357&partnerID=8YFLogxK
U2 - 10.1016/S0040-4020(00)01128-5
DO - 10.1016/S0040-4020(00)01128-5
M3 - Article
AN - SCOPUS:0035843357
VL - 57
SP - 1229
EP - 1234
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 7
ER -