Antihyperglycemic effects of Japanese maple Acer amoenum leaf extract and its constituent corilagin

Atsushi Honma, Tomoyuki Koyama, Kazunaga Yazawa

研究成果: Article査読

10 被引用数 (Scopus)

抄録

The antihyperglycemic effects of the leaves of Acer amoenum and purification and identification of an active compound were investigated. In screening experiments for α-glucosidase inhibitory activity, methanolic extracts of A. amoenum leaves showed potent inhibitory action. This extract showed antihyperglycemic effects in sucrose-loaded mice. Fractionation of the crude extract gave the active compound corilagin [β-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose] by spectroscopic analysis. This is the first report about the possibility of novel utilization of the Japanese maple tree as a source of compounds for prevention or treatment of diabetes mellitus.

本文言語English
ページ(範囲)507-512
ページ数6
ジャーナルJournal of Wood Science
56
6
DOI
出版ステータスPublished - 2010
外部発表はい

ASJC Scopus subject areas

  • Biomaterials

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