Application of cycloolefin polymer chip directly integrated with an electronanospray tip to electrophoretic separation and mass spectrometric detection

Fumihiko Kitagawa, Takafumi Suzuki, Hidetoshi Shinohara, Jun Mizuno, Shuichi Shoji, Koji Otsuka

研究成果: Conference contribution

抄録

This paper reports a fabrication of cycloolefin polymer (COP) chip directly integrated with an electrospray ionization (ESI) emitter tip for a microchip electrophoretic (MCE) separation and mass spectrometric (MS) detection on the basis of the hot embossing, low temperature direct bonding, micromachining techniques and direct metallization onto the COP surface. By applying the fabricated COP chip to the MCE-ESI-MS analysis, a successful separation and detection of caffeine and amino acids was attained without any mechanical pump, nebulizing gas and sheath liquid.

本文言語English
ホスト出版物のタイトルProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
編集者Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
出版社Chemical and Biological Microsystems Society
ページ1405-1407
ページ数3
ISBN(電子版)9780979806407
出版ステータスPublished - 2007
イベント11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
継続期間: 2007 10 72007 10 11

出版物シリーズ

名前Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
国/地域France
CityParis
Period07/10/707/10/11

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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