Application of thermal lens microscopy and sweeping for highly sensitive detection in electrophoretic analysis on cycloolefin polymer microchips

F. Kitagawa, T. Tsuneka, Y. Akimoto, J. Mizuno, S. Shoji, K. Otsuka

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

This paper reports an application of cycloolefin polymer (ZEONEX) as a new commercially available plastic material for microchip electrophoresis (MCE), and an improvement of the detectability for serum and chiral analyses by using sweeping and a thermal lens microscope (TLM) as a detection scheme. In the serum analysis, proteins were successfully detected as sharp peaks on the ZEONEX microchips, while on bare quartz microchips only a broader and weaker peak was observed. On the other hand, chiral analysis of 1-aminoindan on the ZEONEX chip under the sweeping condition provided an efficient separation with a 52-fold sensitivity enhancement.

本文言語English
ホスト出版物のタイトルMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
ホスト出版物のサブタイトル9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Transducer Research Foundation
ページ331-333
ページ数3
ISBN(印刷版)0974361119, 9780974361116
出版ステータスPublished - 2005 1 1
イベント9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
継続期間: 2005 10 92005 10 13

出版物シリーズ

名前Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
1

Conference

Conference9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
CountryUnited States
CityBoston, MA
Period05/10/905/10/13

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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