Applications of vascular occlusion diminish disuse atrophy of knee extensor muscles

Y. Takarada, H. Takazawa, N. Ishii*

*この研究の対応する著者

研究成果: Article査読

207 被引用数 (Scopus)

抄録

Purpose: We have previously shown that the combination of low-intensity resistive exercise and moderate vascular occlusion induces in humans a marked increase in growth hormone secretion and muscular hypertrophy. The present study investigated the effects of vascular occlusion on the size of thigh muscles in patients who underwent an operation for the reconstruction of the anterior cruciate ligament to see whether it attenuates the disuse muscular atrophy without any exercise combined. Methods: Two sessions of occlusive stimulus, each consisting of five repetitions of vascular occlusion (mean maximal pressure, 238 mm Hg) for 5 min and the release of occlusion for 3 min, were applied daily to the proximal end of the thigh from 3rd to 14th days after the operation. Changes in the cross-sectional area (CSA) of thigh muscles were analyzed with magnetic resonance images taken on the 3rd and 14th day after the operation. Results: Without occlusive stimulus (control), the CSAs of knee extensors and flexors decreased by 20.7 ± 2.2% and 11.3 ± 2.6% (mean ± SEM, N = 8), whereas with the occlusive stimulus, they decreased by 9.4 ± 1.6% and 9.2 ± 2.6% (N = 8), respectively. The relative decrease in CSA of knee extensors was significantly (P < 0.05) larger in the control group than in the experimental group. Conclusion: The results indicate that the occlusive stimulus effectively diminishes the postoperation disuse atrophy of knee extensors.

本文言語English
ページ(範囲)2035-2039
ページ数5
ジャーナルMedicine and Science in Sports and Exercise
32
12
DOI
出版ステータスPublished - 2000
外部発表はい

ASJC Scopus subject areas

  • 整形外科およびスポーツ医学
  • 理学療法、スポーツ療法とリハビリテーション

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