Ascorbic acid 2-phosphate enhances albumin mRNA expression and secretion of porcine hepatocytes

Dawei Yang; Toshie Koyama; Ai Okamura; Yoshiaki Shiba; Takayuki Akimoto; Makoto Kodama

doi:10.1016/j.msec.2003.12.015

Ascorbic acid 2-phosphate enhances albumin mRNA expression and secretion of porcine hepatocytes

Dawei Yang, Toshie Koyama, Ai Okamura, Yoshiaki Shiba, Takayuki Akimoto, Makoto Kodama^*

^*この研究の対応する著者

研究成果: Article › 査読

1 被引用数 (Scopus)

抄録

The effect of ascorbic acid 2-phosphate (Asc2P) was tested on porcine and rat mature hepatocytes in vitro. Asc2P enhanced the porcine albumin mRNA expression. The albumin secretion released into the culture medium from the porcine hepatocytes was also increased by Asc2P. However, Asc2P did not give any effects to rat hepatocytes on albumin mRNA expression and albumin secretion. This result shows that Asc2P is one of the important factors to enhance porcine hepatocyte activity.

本文言語	English
ページ（範囲）	323-327
ページ数	5
ジャーナル	Materials Science and Engineering C
巻	24
号	3
DOI	https://doi.org/10.1016/j.msec.2003.12.015
出版ステータス	Published - 2004 4月 1
外部発表	はい

ASJC Scopus subject areas

材料科学（全般）
凝縮系物理学
材料力学
機械工学

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10.1016/j.msec.2003.12.015

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title = "Ascorbic acid 2-phosphate enhances albumin mRNA expression and secretion of porcine hepatocytes",

abstract = "The effect of ascorbic acid 2-phosphate (Asc2P) was tested on porcine and rat mature hepatocytes in vitro. Asc2P enhanced the porcine albumin mRNA expression. The albumin secretion released into the culture medium from the porcine hepatocytes was also increased by Asc2P. However, Asc2P did not give any effects to rat hepatocytes on albumin mRNA expression and albumin secretion. This result shows that Asc2P is one of the important factors to enhance porcine hepatocyte activity.",

keywords = "Albumin, Albumin secretion, Ascorbic acid 2-phosphate, Enzyme-linked immunosorbent assay, Messenger RNA expression, Porcine hepatocytes, Rat hepatocytes, Reverse transcriptase-polymerase chain reaction",

author = "Dawei Yang and Toshie Koyama and Ai Okamura and Yoshiaki Shiba and Takayuki Akimoto and Makoto Kodama",

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doi = "10.1016/j.msec.2003.12.015",

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T1 - Ascorbic acid 2-phosphate enhances albumin mRNA expression and secretion of porcine hepatocytes

AU - Yang, Dawei

AU - Koyama, Toshie

AU - Okamura, Ai

AU - Shiba, Yoshiaki

AU - Akimoto, Takayuki

AU - Kodama, Makoto

PY - 2004/4/1

Y1 - 2004/4/1

N2 - The effect of ascorbic acid 2-phosphate (Asc2P) was tested on porcine and rat mature hepatocytes in vitro. Asc2P enhanced the porcine albumin mRNA expression. The albumin secretion released into the culture medium from the porcine hepatocytes was also increased by Asc2P. However, Asc2P did not give any effects to rat hepatocytes on albumin mRNA expression and albumin secretion. This result shows that Asc2P is one of the important factors to enhance porcine hepatocyte activity.

AB - The effect of ascorbic acid 2-phosphate (Asc2P) was tested on porcine and rat mature hepatocytes in vitro. Asc2P enhanced the porcine albumin mRNA expression. The albumin secretion released into the culture medium from the porcine hepatocytes was also increased by Asc2P. However, Asc2P did not give any effects to rat hepatocytes on albumin mRNA expression and albumin secretion. This result shows that Asc2P is one of the important factors to enhance porcine hepatocyte activity.

KW - Albumin

KW - Albumin secretion

KW - Ascorbic acid 2-phosphate

KW - Enzyme-linked immunosorbent assay

KW - Messenger RNA expression

KW - Porcine hepatocytes

KW - Rat hepatocytes

KW - Reverse transcriptase-polymerase chain reaction

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DO - 10.1016/j.msec.2003.12.015

M3 - Article

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EP - 327

JO - Materials Science and Engineering C

JF - Materials Science and Engineering C

SN - 0928-4931

IS - 3

ER -

Ascorbic acid 2-phosphate enhances albumin mRNA expression and secretion of porcine hepatocytes

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