Assessment of brain mechanisms involved in the processes of thermal sensation, pleasantness/unpleasantness, and evaluation

Yuka Aizawa, Tokiko Harada, Hiroki Nakata, Mizuki Tsunakawa, Norihiro Sadato, Kei Nagashima

    研究成果: Article

    1 引用 (Scopus)

    抄録

    The conscious perception of thermal stimuli is divided into two categories: thermal sensation (i.e., discriminative component) and pleasantness/unpleasantness (i.e., hedonic component). There have been very few studies which clearly dissociated the two components. The aim of the present study was 1) to identify brain regions involved in perception of thermal stimuli per se, dissociating those related to the two components, and additionally 2) to examine brain regions of the explicit evaluation processes for the two components. Sixteen participants received local thermal stimuli of either 41.5 °C or 18.0 °C during whole-body thermal stimuli of 47.0 °C, 32.0 °C, or 17.0 °C. The local stimuli were delivered to the right forearm with the Peltier device. The whole-body stimuli delivered through a water-perfusion suit was aimed to modulate thermal pleasantness/unpleasantness to the local stimulus. The local stimulation at the same temperature was conducted five times with 30-s intervals. Brain activation was assessed by functional magnetic resonance imaging (fMRI), and the participants were asked to report their ratings of thermal sensation and pleasantness/unpleasantness following the cessation of each local stimulus. Local thermal stimulation activated specific brain regions such as the anterior cingulate cortex, insula, and inferior parietal lobe, irrespective of the temperature of local and whole-body stimuli; however, no specific activation for hot or cold sensation was observed. Different brain regions were associated with pleasantness and unpleasantness; the caudate nucleus and frontal regions for pleasantness, and the medial frontal and anterior cingulate cortex for unpleasantness. In addition, the explicit evaluation process for the discriminative and hedonic components immediately following the cessation of local stimulus involved different brain regions; the medial prefrontal cortex extending to the anterior cingulate cortex, insula, middle frontal cortex, and parietal lobes during the explicit evaluation of thermal sensation, and the medial prefrontal cortex, posterior cingulate cortex, and inferior parietal lobes during that of pleasantness/unpleasantness.

    元の言語English
    ページ(範囲)54-63
    ページ数10
    ジャーナルIBRO Reports
    6
    DOI
    出版物ステータスPublished - 2019 6 1

    Fingerprint

    Hot Temperature
    Brain
    Gyrus Cinguli
    Parietal Lobe
    Pleasure
    Frontal Lobe
    Prefrontal Cortex
    Temperature
    Caudate Nucleus
    Forearm
    Perfusion
    Magnetic Resonance Imaging
    Equipment and Supplies
    Water

    Keywords

      ASJC Scopus subject areas

      • Neuroscience(all)

      これを引用

      Assessment of brain mechanisms involved in the processes of thermal sensation, pleasantness/unpleasantness, and evaluation. / Aizawa, Yuka; Harada, Tokiko; Nakata, Hiroki; Tsunakawa, Mizuki; Sadato, Norihiro; Nagashima, Kei.

      :: IBRO Reports, 巻 6, 01.06.2019, p. 54-63.

      研究成果: Article

      Aizawa, Yuka ; Harada, Tokiko ; Nakata, Hiroki ; Tsunakawa, Mizuki ; Sadato, Norihiro ; Nagashima, Kei. / Assessment of brain mechanisms involved in the processes of thermal sensation, pleasantness/unpleasantness, and evaluation. :: IBRO Reports. 2019 ; 巻 6. pp. 54-63.
      @article{f1fbc1c81b724d13a0dfc94021078a80,
      title = "Assessment of brain mechanisms involved in the processes of thermal sensation, pleasantness/unpleasantness, and evaluation",
      abstract = "The conscious perception of thermal stimuli is divided into two categories: thermal sensation (i.e., discriminative component) and pleasantness/unpleasantness (i.e., hedonic component). There have been very few studies which clearly dissociated the two components. The aim of the present study was 1) to identify brain regions involved in perception of thermal stimuli per se, dissociating those related to the two components, and additionally 2) to examine brain regions of the explicit evaluation processes for the two components. Sixteen participants received local thermal stimuli of either 41.5 °C or 18.0 °C during whole-body thermal stimuli of 47.0 °C, 32.0 °C, or 17.0 °C. The local stimuli were delivered to the right forearm with the Peltier device. The whole-body stimuli delivered through a water-perfusion suit was aimed to modulate thermal pleasantness/unpleasantness to the local stimulus. The local stimulation at the same temperature was conducted five times with 30-s intervals. Brain activation was assessed by functional magnetic resonance imaging (fMRI), and the participants were asked to report their ratings of thermal sensation and pleasantness/unpleasantness following the cessation of each local stimulus. Local thermal stimulation activated specific brain regions such as the anterior cingulate cortex, insula, and inferior parietal lobe, irrespective of the temperature of local and whole-body stimuli; however, no specific activation for hot or cold sensation was observed. Different brain regions were associated with pleasantness and unpleasantness; the caudate nucleus and frontal regions for pleasantness, and the medial frontal and anterior cingulate cortex for unpleasantness. In addition, the explicit evaluation process for the discriminative and hedonic components immediately following the cessation of local stimulus involved different brain regions; the medial prefrontal cortex extending to the anterior cingulate cortex, insula, middle frontal cortex, and parietal lobes during the explicit evaluation of thermal sensation, and the medial prefrontal cortex, posterior cingulate cortex, and inferior parietal lobes during that of pleasantness/unpleasantness.",
      keywords = "Behavioral thermoregulation, Body temperature, Discriminative component, fMRI, Hedonic component, Insula, Prefrontal cortex, Thermal feeling, Thermal perception",
      author = "Yuka Aizawa and Tokiko Harada and Hiroki Nakata and Mizuki Tsunakawa and Norihiro Sadato and Kei Nagashima",
      year = "2019",
      month = "6",
      day = "1",
      doi = "10.1016/j.ibror.2019.01.003",
      language = "English",
      volume = "6",
      pages = "54--63",
      journal = "IBRO Reports",
      issn = "2451-8301",
      publisher = "Elsevier Limited",

      }

      TY - JOUR

      T1 - Assessment of brain mechanisms involved in the processes of thermal sensation, pleasantness/unpleasantness, and evaluation

      AU - Aizawa, Yuka

      AU - Harada, Tokiko

      AU - Nakata, Hiroki

      AU - Tsunakawa, Mizuki

      AU - Sadato, Norihiro

      AU - Nagashima, Kei

      PY - 2019/6/1

      Y1 - 2019/6/1

      N2 - The conscious perception of thermal stimuli is divided into two categories: thermal sensation (i.e., discriminative component) and pleasantness/unpleasantness (i.e., hedonic component). There have been very few studies which clearly dissociated the two components. The aim of the present study was 1) to identify brain regions involved in perception of thermal stimuli per se, dissociating those related to the two components, and additionally 2) to examine brain regions of the explicit evaluation processes for the two components. Sixteen participants received local thermal stimuli of either 41.5 °C or 18.0 °C during whole-body thermal stimuli of 47.0 °C, 32.0 °C, or 17.0 °C. The local stimuli were delivered to the right forearm with the Peltier device. The whole-body stimuli delivered through a water-perfusion suit was aimed to modulate thermal pleasantness/unpleasantness to the local stimulus. The local stimulation at the same temperature was conducted five times with 30-s intervals. Brain activation was assessed by functional magnetic resonance imaging (fMRI), and the participants were asked to report their ratings of thermal sensation and pleasantness/unpleasantness following the cessation of each local stimulus. Local thermal stimulation activated specific brain regions such as the anterior cingulate cortex, insula, and inferior parietal lobe, irrespective of the temperature of local and whole-body stimuli; however, no specific activation for hot or cold sensation was observed. Different brain regions were associated with pleasantness and unpleasantness; the caudate nucleus and frontal regions for pleasantness, and the medial frontal and anterior cingulate cortex for unpleasantness. In addition, the explicit evaluation process for the discriminative and hedonic components immediately following the cessation of local stimulus involved different brain regions; the medial prefrontal cortex extending to the anterior cingulate cortex, insula, middle frontal cortex, and parietal lobes during the explicit evaluation of thermal sensation, and the medial prefrontal cortex, posterior cingulate cortex, and inferior parietal lobes during that of pleasantness/unpleasantness.

      AB - The conscious perception of thermal stimuli is divided into two categories: thermal sensation (i.e., discriminative component) and pleasantness/unpleasantness (i.e., hedonic component). There have been very few studies which clearly dissociated the two components. The aim of the present study was 1) to identify brain regions involved in perception of thermal stimuli per se, dissociating those related to the two components, and additionally 2) to examine brain regions of the explicit evaluation processes for the two components. Sixteen participants received local thermal stimuli of either 41.5 °C or 18.0 °C during whole-body thermal stimuli of 47.0 °C, 32.0 °C, or 17.0 °C. The local stimuli were delivered to the right forearm with the Peltier device. The whole-body stimuli delivered through a water-perfusion suit was aimed to modulate thermal pleasantness/unpleasantness to the local stimulus. The local stimulation at the same temperature was conducted five times with 30-s intervals. Brain activation was assessed by functional magnetic resonance imaging (fMRI), and the participants were asked to report their ratings of thermal sensation and pleasantness/unpleasantness following the cessation of each local stimulus. Local thermal stimulation activated specific brain regions such as the anterior cingulate cortex, insula, and inferior parietal lobe, irrespective of the temperature of local and whole-body stimuli; however, no specific activation for hot or cold sensation was observed. Different brain regions were associated with pleasantness and unpleasantness; the caudate nucleus and frontal regions for pleasantness, and the medial frontal and anterior cingulate cortex for unpleasantness. In addition, the explicit evaluation process for the discriminative and hedonic components immediately following the cessation of local stimulus involved different brain regions; the medial prefrontal cortex extending to the anterior cingulate cortex, insula, middle frontal cortex, and parietal lobes during the explicit evaluation of thermal sensation, and the medial prefrontal cortex, posterior cingulate cortex, and inferior parietal lobes during that of pleasantness/unpleasantness.

      KW - Behavioral thermoregulation

      KW - Body temperature

      KW - Discriminative component

      KW - fMRI

      KW - Hedonic component

      KW - Insula

      KW - Prefrontal cortex

      KW - Thermal feeling

      KW - Thermal perception

      UR - http://www.scopus.com/inward/record.url?scp=85059701718&partnerID=8YFLogxK

      UR - http://www.scopus.com/inward/citedby.url?scp=85059701718&partnerID=8YFLogxK

      U2 - 10.1016/j.ibror.2019.01.003

      DO - 10.1016/j.ibror.2019.01.003

      M3 - Article

      VL - 6

      SP - 54

      EP - 63

      JO - IBRO Reports

      JF - IBRO Reports

      SN - 2451-8301

      ER -