Astaxanthin production in a model cyanobacterium synechocystis sp. PCC 6803

Naoya Shimada, Yukiko Okuda, Kaisei Maeda, Daisuke Umeno, Shinichi Takaichi, Masahiko Ikeuchi*

*この研究の対応する著者

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Heterologous production of a useful carotenoid astaxanthin was achieved in a cyanobacterium Synechocystis sp. PCC 6803 with the aid of marine bacterial genes. Astaxanthin and its intermediates emerged at high levels, whereas β-carotene and zeaxanthin disappeared in the strain. Total carote-noid accumulation was nearly two fold compared with wild type. The astaxanthin-producing strain was capable of only growing heterotrophically, which was likely due to the absence of β-carotene. Further enhanced accumulation was pursued by gene overexpression for possible rate-limiting steps in the biosynthesis pathway.

本文言語English
ページ(範囲)116-120
ページ数5
ジャーナルJournal of General and Applied Microbiology
66
2
DOI
出版ステータスPublished - 2020
外部発表はい

ASJC Scopus subject areas

  • 微生物学
  • 応用微生物学とバイオテクノロジー

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