Asymmetric rotational stroke in mouse node cilia during left-right determination

Atsuko Takamatsu*, Takuji Ishikawa, Kyosuke Shinohara, Hiroshi Hamada

*この研究の対応する著者

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Rotational movement of isolated single cilia in mice embryo was investigated, which generates leftward fluid flow in the node cavity and plays an important role in left-right determination. The leftward unidirectional flow results from tilting of the rotational axis of the cilium to the posterior side. By combining computational fluid dynamics with experimental observations, we demonstrate that the leftward stroke can be more effective than expected for cases in which cilia tilting alone is considered with the no-slip condition under constant driving torque. Our results suggest that the driving torque is asymmetric.

本文言語English
論文番号050701
ジャーナルPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
87
5
DOI
出版ステータスPublished - 2013 5 15

ASJC Scopus subject areas

  • 統計物理学および非線形物理学
  • 統計学および確率
  • 凝縮系物理学

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