Asynchrony in the growth and motility responses to environmental changes by individual bacterial cells

Senkei Umehara, Akihiro Hattori, Ippei Inoue, Kenji Yasuda*

*この研究の対応する著者

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Knowing how individual cells respond to environmental changes helps one understand phenotypic diversity in a bacterial cell population, so we simultaneously monitored the growth and motility of isolated motile Escherichia coli cells over several generations by using a method called on-chip single-cell cultivation. Starved cells quickly stopped growing but remained motile for several hours before gradually becoming immotile. When nutrients were restored the cells soon resumed their growth and proliferation but remained immotile for up to six generations. A flagella visualization assay suggested that deflagellation underlies the observed loss of motility. This set of results demonstrates that single-cell transgenerational study under well-characterized environmental conditions can provide information that will help us understand distinct functions within individual cells.

本文言語English
ページ(範囲)464-469
ページ数6
ジャーナルBiochemical and Biophysical Research Communications
356
2
DOI
出版ステータスPublished - 2007 5月 4
外部発表はい

ASJC Scopus subject areas

  • 生物理学
  • 生化学
  • 分子生物学
  • 細胞生物学

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