Bacterial inactivation by applying an alternating electromagnetic field using PAMAM dendron-modified magnetic nanoparticles

Atsushi Arakaki, Mami Takahashi, Masahito Hosokawa, Tadashi Matsunaga, Tsuyoshi Tanaka*

*この研究の対応する著者

研究成果: Article査読

4 被引用数 (Scopus)

抄録

In this study, a method involving polyamidoamine dendron-modified magnetic nanoparticles (PAMAM-MNPs) along with application of an alternating magnetic field (AMF) was developed for inactivation of bacteria in water samples. The PAMAM-MNPs efficiently bound to Escherichia coli cells, resulting in magnetic recovery of cells from aqueous solutions. By applying the AMF (5kW, 250 kHz) to the cell suspension, E. coli cells were successfully inactivated within 10 min in the presence of the MNPs, while no effect was observed in the absence of the MNPs. The use of PAMAM-MNPs could increase the inactivation rate of E. coli under the applied AMF. E. coli cells with PAMAM-MNPs stained by propidium iodide (PI) exhibited apparent fluorescence after exposure to the AMF, suggesting the occurrence of membrane damage in the cells because of direct heat transfer from the PAMAM-MNPs. Our technique can be used to address bacterial contamination with wide varieties of microorganisms in water samples.

本文言語English
ページ(範囲)324-327
ページ数4
ジャーナルElectrochemistry
84
5
DOI
出版ステータスPublished - 2016 5月
外部発表はい

ASJC Scopus subject areas

  • 電気化学

フィンガープリント

「Bacterial inactivation by applying an alternating electromagnetic field using PAMAM dendron-modified magnetic nanoparticles」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル