Biomagnetic nanoparticle formation and application

T. Matsunaga, H. Takeyama

研究成果: Conference article査読

42 被引用数 (Scopus)

抄録

Magnetospirillum sp. AMB-1 is a bacterium that synthesizes intracellular particles of magnetite (Fe3O4). A magA gene required for the synthesis of bacterial magnetic particles (BMPs) was isolated from this strain and its gene product (MagA protein) was characterized as an iron transport protein. Intracellular localization analysis of the MagA protein using magA-Luc fusion proteins showed that MagA protein is localized on the surface of the lipid bilayer covering the BMPs. One particular BMP-associated protein, designated MpsA, was also purified from this strain and characterized. By the fusion-protein method using mpsA-luc genes, it was demonstrated that Mps-protein is preferentially partitioned onto the BMP membrane. Furthermore, application of BMPs to immunoassay is also described.

本文言語English
ページ(範囲)391-394
ページ数4
ジャーナルSupramolecular Science
5
3-4
DOI
出版ステータスPublished - 1998 1 1
外部発表はい
イベントProceedings of the 11th Toyota Conference on Nanostructured Materials in Biological and Artificial Systems - Shizuoka, Jpn
継続期間: 1997 11 51997 11 8

ASJC Scopus subject areas

  • Engineering(all)

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