Blood flow responses in celiac and superior mesenteric arteries in the initial phase of digestion

Nami Someya, Masako Yamaoka Endo, Yoshiyuki Fukuba, Naoyuki Hayashi*

*この研究の対応する著者

研究成果: Article査読

43 被引用数 (Scopus)

抄録

Blood flow (BF) responses in the celiac artery (CA) and superior mesenteric artery (SMA) during and immediately after a meal are poorly understood. We characterized postprandial BF responses in these arteries in the initial phase of digestion. After a baseline measurement in the overnight fasting state, healthy subjects ingested solid food (300 kcal) and water ad libitum within 5 min (4.6 ± 0.2 min, means ± SE), and then rested for 60 min in the postprandial state. Mean blood velocities (MBVs) in CA (n = 7) and SMA (n = 9) and mean arterial pressure (MAP) were measured throughout the procedure. The MAP was divided by the MBV to yield the resistance index (RI). The MBV in CA and SMA started increasing within a minute after beginning the meal. The MBV in CA rapidly reached its peak increase (60 ± 8% change from baseline) at 5 ± 1 min after the start of the meal, whereas the MBV in SMA gradually reached its peak increase (134 ± 14%) at 41 ± 4 min after the start of the meal, reflecting a decrease in the RI for both CA and SMA. These findings suggested an earlier increase in CA and SMA MBV, implying that the increase of BF in some parts of the small intestine precedes the arrival of chyme.

本文言語English
ページ(範囲)R1790-R1796
ジャーナルAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
294
6
DOI
出版ステータスPublished - 2008 6
外部発表はい

ASJC Scopus subject areas

  • 生理学
  • 生理学(医学)

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