Calf circumference as a surrogate marker of muscle mass for diagnosing sarcopenia in Japanese men and women

Ryoko Kawakami, Haruka Murakami, Kiyoshi Sanada, Noriko Tanaka, Susumu S. Sawada, Izumi Tabata, Mitsuru Higuchi, Motohiko Miyachi

研究成果: Article査読

122 被引用数 (Scopus)

抄録

Aim: To examine the relationship between calf circumference and muscle mass, and to evaluate the suitability of calf circumference as a surrogate marker of muscle mass for the diagnosis of sarcopenia among middle-aged and older Japanese men and women. Methods: A total of 526 adults aged 40-89 years participated in the present cross-sectional study. The maximum calf circumference was measured in a standing position. Appendicular skeletal muscle mass was measured using dual-energy X-ray absorptiometry, and the skeletal muscle index was calculated as appendicular skeletal muscle mass divided by the square of the height (kg/m2). The cut-off values for sarcopenia were defined as a skeletal muscle index of less than -2 standard deviations of the mean value for Japanese young adults, as defined previously. Results: Calf circumference was positively correlated with appendicular skeletal muscle (r=0.81 in men, r=0.73 in women) and skeletal muscle index (r=0.80 in men, r=0.69 in women). In receiver operating characteristic analysis, the optimal calf circumference cut-off values for predicting sarcopenia were 34cm (sensitivity 88%, specificity 91%) in men and 33cm (sensitivity 76%, specificity 73%) in women. Conclusions: Calf circumference was positively correlated with appendicular skeletal muscle mass and skeletal muscle index, and could be used as a surrogate marker of muscle mass for diagnosing sarcopenia. The suggested cut-off values of calf circumference for predicting low muscle mass are <34cm in men and <33cm in women.

本文言語English
ページ(範囲)969-976
ページ数8
ジャーナルGeriatrics and Gerontology International
15
8
DOI
出版ステータスPublished - 2015 8 1
外部発表はい

ASJC Scopus subject areas

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

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